Staff Directory


Mohd Hafiz Bin Arzmi

Academic Qualification

  • Ph.D - Medicine, Dentistry & Health Sciences - Doctor of Philosophy, University of Melbourne
  • Master of Dental Science - Masters Degree, Universiti Malaya (UM)
  • Islamic Studies - Post Graduate Diploma, International Islamic University Malaysia
  • BSc. (Microbiology) with Hons. - Bachelor Degree, Universiti Malaya (UM)
  • Certificate in Health and Safety - Certificate, University of Melbourne

Mohd Hafiz Bin Arzmi (Assoc. Prof. Ts. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF DENTISTRY

Other's position:

Deputy Director, Research Management Centre


hafizarzmi@iium.edu.my
2946


Expert Profile


Dr Mohd Hafiz Arzmi is a passionate microbiologist, immunologist, and inventor. His expertise includes polymicrobial interactions, biofilms, microbiomes, probiotics, and oral carcinogenesis.
He is currently the Deputy Director, Technology Transfer Office (TTO), Research Management Centre (RMC), IIUM, the Honorary (Fellow) of Melbourne Dental School, The University of Melbourne, Australia, the Chair of Science Integrity for the Young Scientist Network Academy of Science Malaysia (YSN-ASM), the executive member of the International Association for Dental Research (IADR), Malaysian Section and the executive member for Malaysian Society for Oral Microbiologist and Oral Immunologist (MySOMOI). He is also the Head of the Cluster of Cancer Research Initiative IIUM (COCRII), leading a transdisciplinary study in cancer research in East Coast Malaysia. He is also the founder of the B-Five group to support young researchers at IIUM Kuantan Campus. He was formerly the Deputy Dean of Student Development and Community Engagement, Kulliyyah of Dentistry, IIUM (2021-2023) and the Head of Grant Management Unit, RMC, IIUM (2018-2021).
Since 2008, he has been working on Candida species which has been reported to involve oral carcinogenesis at the Faculty of Dentistry, the University of Malaya, where he discovered the important role of phenotypic switching in the pathogenicity of Candida spp. In 2012, he continued his journey to find the relationship between polymicrobial infection to the development of oral cancer at Melbourne Dental School, The University of Melbourne, Australia, which he had successfully linked the development of oral cancer to polymicrobial interactions of Candida albicansStreptococcus mutans, and Actinomyces naeslundii.
He has been actively publishing in many journals, books and newspapers in microbiology, immunology, machine learning and ethics. He is currently supervising post-doctoral, PhD, Master, Interns, and Final Year Project (FYP) students, both local and international. He has secured various prestigious national, international and industrial grants, including Fundamental Research Grant Scheme (FRGS), Prototype Research Grant Scheme (PRGS), MyOHUN, etc. He won various awards, including a gold medal and a special award at Malaysia Technology Expo (MTE) 2022. Among his commercialised product is Oral Synbiotic (OroSYN) toothpaste and probiotic gummies.  He also works closely with industries PETRONAS, NFA Technologies Sdn Bhd, Regal Malay Capital Berhad and Jardin Pharma Berhad.
He actively contributes to the community by disseminating Islamic knowledge by engaging various communities, including Australian Malay Foundation, MECCA, Sri Lankan Islamic Society Melbourne, etc. He was also the Imam at Masjid Al-Fateh, Coburg and Brunswick Mosque, Melbourne, from 2012 until 2016. He is also the Imam and Khatib at Sultan Haji Ahmad Shah Mosque, IIUM Kuantan Campus.  "Be the best as you can, as paradise is waiting for you" has been the key to his success.    


Area of Specialisation


  • Natural Science ~ Biological Sciences ~ Microbiology ~ Medical Microbiology
  • Natural Science ~ Biological Sciences ~ Microbiology ~ Immunology - Cytokines expression, flow cytometry, adhesion assay, Epithelial mesenchymal transition
  • Medical And Health ~ Medical And Health Sciences ~ Medical Microbiology ~ Bacteriology - Streptococcus and Actinomyces
  • Natural Science ~ Biological Sciences ~ Microbiology ~ Medical Microbiology - Biofilm and microbiome
  • Medical And Health ~ Medical And Health Sciences ~ Medical Microbiology ~ Mycology - Candida species


Professional Membership


  • 2012 - 2019: Member of Profesional Body / Association: (Member), Australian Society for Microbiology
  • 2012 - 2016: Member of Profesional Body / Association: (Member), Oral Health Cooperative Research Centre, Australia
  • 2012 - 2019: Member of Profesional Body / Association: (Member), International Association for Dental Research (Australia New Zealand section)
  • 2017 - 2021: Member of Profesional Body / Association: (Member), International Society for Human and Anima Mycology (ISHAM)
  • 2018 - 2020: Member of Profesional Body / Association: (Executive member), International Association for Dental Research (Malaysian Section)
  • 2018 - 2022: Member of Profesional Body / Association: (Vice-President), Malaysian Society for Oral Microbiology Oral Immunology
  • 2018 - 2019: Member of Profesional Body / Association: (Member), American Society for Microbiology
  • 2018 - 2022: Member of Profesional Body / Association: (Member), Malaysian Society for Microbiology
  • 2018 - 2021: Member of Profesional Body / Association: (Member), Society for Applied Microbiology (SfAM)
  • 2020 - 2023: Member of Profesional Body / Association: (Full member), Young Scientist Network - Academy of Sciences Malaysia


Teaching Responsibilities


ADVANCED IMMUNOLOGY 2021/2022 2020/2021 2017/2018
BASIC IMMUNOLOGY 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018
BASIC MICROBIOLOGY & IMMUNOLOGY 2020/2021 2019/2020
BIOCHEMISTRY 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018
BODY REACTIONS TO PHYSICAL, CHEMICAL AND BIOLOGICAL AGENTS 2023/2024
FAMILY MANAGEMENT 2022/2023 2021/2022
FAMILY MANAGEMENT AND PARENTING 2020/2021 2019/2020 2018/2019 2017/2018
IMMUNOLOGY 2019/2020 2018/2019 2017/2018
IMMUNOLOGY AND HAEMATOLGY LABORATORY PRACTICES 2020/2021 2019/2020
IMMUNOLOGY AND HAEMATOLOGY LABORATORY PRACTICES 2023/2024 2022/2023 2021/2022 2020/2021
MICROBIOLOGY & IMMUNOLOGY 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018
ORTHODONTICS 2021/2022
PHARMACEUTICAL MICROBIOLOGY 2017/2018
SUSTAINABLE DEVELOPMENT: ISSUES, PRINCIPLES AND PRACTICES 2023/2024 2022/2023
USRAH IN ACTION 1 2021/2022
USRAH IN ACTION 2 2022/2023


Supervision


Elucidation On The Effect Of Probiotic Streptococcus Salivarius K12 On The Virulence Factors Of Candida Albicans And Its Role In Oral Carcinogenesis.
Ph.D Completed 2023 Main Supervisor
Elucidation Of Crispr/Cas9 Ece1 Knockout And Functional Study Of Candidalysin In Polymicrobial Interactions Of Candida Albicans With Streptococcus Salivarius K12.
Ph.D In Progress Main Supervisor
Elucidation On The Role Of Phenotypic Switching Of Candida Auris In Oral Squamous Cell Carcinoma (Oscc) In Vitro Model.
Ph.D In Progress Main Supervisor
Elucidating The Role Of Polymicrobial Interactions Of Candida Auris And Staphylococcus Aureus In In-Vitro Oscc Model.
Ph.D In Progress Main Supervisor
Antimicrobial And Antibiofilm Abilities Of Theobromine Extract-Coated Orthodontic Archwires Towards Candida Albicans And Streptococcus Mutans..
Ph.D In Progress Co-supervisor
The Effect Of Tymoquinone On Candida Albicans And Staphylococcus Aureus On Pmma In Monoculture And Co-Culture Condition.
Ph.D In Progress Co-supervisor
Fabrication And Characterization Of Fish-Derived Collagen/ Chitosan Membrane Loaded With Metronidazole Chitosan Nanoparticle For Periodontal Bone Regeneration.
Ph.D In Progress Co-supervisor
Elucidation On The Effect Of Theobroma Cacao Aqueous Extract (Cocoa) On The Susceptibility And Biofilm-Forming Ability Of Streptococcus Mutans On Nickel-Titanium And Stainless-Steel Orthodontic Archwires.
Ph.D In Progress Co-supervisor
Characterization Of Mitragyna Speciosa And Evaluation Of Antioxidant, Cytotoxicity And Antimicrobial Activity Against Oral Pathogens.
Ph.D In Progress Co-supervisor
In Vitro Study Of Anti-Inflammatory Activity Of Syzygium Polyanthum And Its Antimicrobial And Antibiofilm Againts Candida Spp. On Diffrent Type Of Denture Bases.
Ph.D In Progress Co-supervisor
Determination Of Ld50 And The Efficacy Of Synbiotic Mouthwash Containing Streptococcus Salivarius K12 And Musa Acuminata Peel Extract Against Oral Candidiasis In Rat'S Model.
Master Completed 2023 Main Supervisor
Elucidation Of Crispr-Cas9 Site-Directed Mutagenesis On Third Lysine-Arginine Motif In Candida Albicans Ece1 Gene.
Master Completed 2023 Main Supervisor
Characterisation Of Candida Albicans Strain (Cocrii-Ac01) Isolated From Autistic Child With Caries, Its Susceptibility And Biofilm-Forming Ability Towards Gold, Silver And Bimetallic Gold-Silver Nanoclusters.
Master Completed 2023 Main Supervisor
The Association Between Stress And Fear Of Covid-19 With Salivary Immunoglobulin A Level Among Nurses At Sultan Ahmad Shah Medical Centre (Sasmec @Iium): A Cross Sectional Study.
Master Completed 2023 Co-supervisor
Characterization, Cytotoxicity Evaluation, And Effects Of Cervus Timorensis Velvet Antler Aqueous Extract On Candida Albicans’S Growth And Biofilm Formation .
Master Completed 2023 Co-supervisor
Comparative Genomic And Evolutionary Relationship Analysis In Identification Of Actinomyces Naeslundii Probiotic Properties- Related Proteins .
Master Completed 2021 Co-supervisor
The Effect Of Streptococcus Salivarius And Actinomyces Naeslundii In Combination With Musa Acuminata Extract On The Biological Properties Of Candida Albicans .
Master Completed 2020 Main Supervisor
The Effects Of Probiotics And Actinomyces Naeslundii On Oral Carcinogenesis .
Master Completed 2020 Co-supervisor
Characterization Of Mitragyna Speciosa (Kratom) Via Metabolomics Study And Its Effect On Candida Species Virulence Factors.
Master In Progress Main Supervisor
Synthesis Of Postbiotic Gold Nanoparticles (K12-Aunp) And Its Effect On The Susceptibility And Growth Of Candida Auris.
Master In Progress Main Supervisor
Elucidation On The Effect Of Postbiotic-Gold Nanoparticle (K12-Aunps) On Candida Auris Biofilm And Its Cytotocix, Migration And Pro-Inflammatory Cytokines Activities.
Master In Progress Main Supervisor
Development Of Micro-Encapsulated Synbiotic Streptococcus Salivarius K12 And Musa Acuminata Extract (Orosyn©) And Its Effect On Candida Albicans Biofilm.
Master In Progress Main Supervisor
Development Of Detoxified Standardized Extract Of Mitragyna Speciosa And In-Vitro Toxicity Study .
Master In Progress Co-supervisor
Analysing The Prevalence Of Tooth Wear And Its Associated Factors Among Young Adolescents In Kuantan.
Master In Progress Co-supervisor
Genome Sequencing And Analysis Of Mitragyna Speciosa (Kratom) Isolated From Malaysia.
Master In Progress Co-supervisor
The Role Of Jacalin In The Inhibition Of Oral Cancer Cell Transformation Determining The Mechanism Of Jacalin In The Inhibition Of Oral Cancer Cell Transformation.
Master In Progress Co-supervisor
Elucidation On The Antimicrobial Effect Of Syzygium Cumini Seed Extract On Oral Mucositis Pathogens..
Master In Progress Co-supervisor


Research Projects


Completed
2022 - 2024 OPTIMISATION AND FORMULATION OF SYNBIOTIC TOOTHPASTE
2021 - 2023 Deep Transfer Learning-Based Approach for Image Classification of Breast Cancer Mammogram
2021 - 2022 Determination of Anti-biofilm Property of Lactobacillus Rhamnosus towards Candida Albicans.
2021 - 2022 Empowerment of COVID-19 affected Green rose (Rosadiflora species) industry by transferring knowledge on the extraction and soap making to increase product quality and variety.
2021 - 2023 The examination of perception and association of authentic local food in Perlis among tourists and the people of Perlis for the purpose of food destination marketing
2020 - 2024 Elucidating the role of microbiome in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma
2020 - 2023 Prototype development of an organic and halal oral synbiotic (OroSYN) mouthwash containing Streptococcus salivarius and Pisang Emas skin extract.
2020 - 2022 Elucidation on the Antimicrobial Property of SES Sterilisation Electrolyte Solution towards Human Pathogens
2020 - 2021 Elucidation on the Antimicrobial Property of Rosadiflora Species towards Human Pathogen
2019 - 2023 Antimicrobial, immunological and tooth remineralisation effect of Deer velvet antler of Cervus timorensis.
2019 - 2021 Effectiveness of Snoezelen Therapy in Improving Oral Health Practices Among Special Needs Children
2018 - 2022 Ascorbic Acid PLGA Nanoparticles Incorporated With Carbopol-Honey Oral Gel Intended To Treat Oral Squamous Cell Carcinoma
2018 - 2020 Elucidation of the role of oral microbiome in promoting healthy oral cavity and pathogenesis
2018 - 2021 Elucidation of Candida albicans candidalysin mechanism in polymicrobial biofilms with Actinomyces naeslundii and Streptococcus mutans using flow cell model
2018 - 2021 Identification of Actinomyces naeslundii as a potential oral probiotic using in silico approaches
2018 - 2021 Cell Viability, Biochemical and Histological Evaluation of Three-Dimensional Fish-derived Collagen-Chitosan-Glycerin Scaffold for Oral Mucosa Regeneration.
2017 - 2019 The effect of polymicrobial interaction to the virulence factors of Candida albicans
On-Going
2024 - Present Antimicrobial and Antibiofilm Abilities of Theobromine from Theobroma Cacao Treated Nickel Titanium and Stainless Steel Orthodontics Archwires Towards Candida Albicans and Streptococcus Mutans
2024 - Present Training Workshop on Biosecurity Issues Related to Clinical and Natural Product Research
2023 - Present Elucidating the mechanism of Kelulut propolis as an anticandidal, antibiofilm and anti-inflammatory agent using Denture Associated Stomatitis (DAS) model.
2023 - Present Training of Trainer (TOT) on the Responsible Conduct of Toxin and Venom Research: The Role Biosafety, Biosecurity and Cyberbiosecurity
2022 - Present EVALUATION OF THE PROPERTIES OF LACTOBACILLUS HELVETICUS ON THE FIMBRIAE GENES OF PORPHYROMONAS GINGIVALIS IN SUBGINGIVAL BIOFILM ASSOCIATED WITH PERIODONTITIS
2022 - Present Kinetic mechanism and diffusion release study of ? tocopherol/Camellia sinensis active compounds incorporated with active cn-film in food model systems.
2022 - Present Early breast cancer detection and classifying from mammograms using deep neural network.
2022 - Present Elucidation on the Effect of Theobroma Cacao (Cocoa) Extract on the Susceptibility and Biofilm Ability of Streptococcus Mutans on Nickel Titanium and Stainless Steel Orthodontic Archwires
2022 - Present Elucidation on the mechanism of postbiotic-gold nanoparticles (K12-AuNPs) on the inhibition of Candida auris virulence factors in oral cancer candidiasis model.
2022 - Present Determining the mechanism of Jackfruit seed-derived-Lectin (Jacalin) in the inhibition of oral cancer cell transformation
2022 - Present Effect of processing parameters on physico-chemical and biological properties of goose bone nanoparticles
2022 - Present Characterization on the Properties of Mitragyna Speciosa, Deletion of Toxicity Genes, Development of Kratom-Based Medicinal Products and It's Legal Implication
2021 - Present The Relationship Between Stress, Fear of Covid-19, and Salivary Immunoglobulin A Level Among Staff Nurse at SASMEC : A Cross Sectional Study
2020 - Present Immunomodulatory effect of Tualang Honey on oral wound healing in diabetic Wistar rats
2020 - Present Elucidating the role of miR-21 in oral potentially malignant disorders and oral squamous cell carcinoma
2020 - Present Elucidation of antimicrobial and antibiofilm activities of Rosa chinensis . as potential agent for Osteomyelitis treatment.
2020 - Present Elucidation on the antimicrobial and antibiofilm activities of Theobroma cacao (cocoa) towards Streptococcus mutans on orthodontics archwires
2020 - Present Elucidation on the antimicrobial effect of Syzygium cumini seed extract on oral mucositis pathogens.
2020 - Present Eurycoma Longifolia Jack (Tongkat Ali) as a New Dental Mouthwash
2019 - Present Evaluation of Novel Fish-Derived Collagen/Chitosan Membrane Loaded with Metronidazole Nanoparticle As Guided Bone Regeneration for Periodontal Regeneration.
2019 - Present Optimisation of corneal stromal lenticules in vitro using retinoid acid-supplemented medium


Award & Recognition


01 Dec, 2022 Top 50 Contributors to IIUM Research Performance - International Islamic University Malaysia University
17 Oct, 2022 Gold Medal - SDG International Innovation Awards and Expo, Malaysia Technology Expo (MTE) International
17 Oct, 2022 Special award for outstanding innovation in health & well-being, MSMBB - SDG International Innovation Awards and Expo, Malaysia Technology Expo (MTE) International
31 Mar, 2022 Top Cited Articles 2020-2021 - Wiley International
14 Feb, 2022 Murabbi Award Preclinical Lecturer - International Islamic University Malaysia University
14 Feb, 2022 Promising Researcher Award - International Islamic University Malaysia University
04 Dec, 2021 Bronze Medal - Korea Invention Promotion Association International
10 Oct, 2021 CONGRATULATORY MESSAGE ? Top Researchers with the highest amount of grants received from 2019 -2021 - International Islamic University Malaysia University
27 Aug, 2021 First runner up - Kulliyyah of Dentistry, IIUM University
10 Aug, 2021 Gold Medal - Universiti Teknologi Mara (UiTM) International
04 Jun, 2021 Best Poster Award - 3rd World Congress on Integration & Islamicisation 2021 International
22 Mar, 2021 Silver Medal - International Expo on Inventions and Innovations, Malaysia Technology Expo (MTE) International
22 Feb, 2020 Silver Medal - The 19th International Expo on Inventions and Innovations, Malaysia Technology Expo International
22 Feb, 2020 Merit Award - The Malaysia-Croatia Technology Exchange 2020, Republic of Croatia International
04 May, 2019 Silver Award - 31st International Invention, Innovation and Technology Exhibition International
30 Mar, 2019 Joseph Lister travel awards - International Association for Dental Research International
14 Aug, 2018 Best oral presenter - International Conference of Oral Immunology and Oral Microbiology International