Staff Directory


Nurasyikin Binti Hamzah

Academic Qualification

  • Ph.D in Chemistry - Doctor of Philosophy, University of Leeds

Nurasyikin Binti Hamzah (Dr.)

Assistant Professor
IIUM Kuantan Campus

KULLIYYAH OF SCIENCE


nurasyikinhamzah@iium.edu.my
5182


Area of Specialisation


  • Natural Science ~ Chemical Sciences ~ Organic Chemistry ~ Medicinal Chemistry


Teaching Responsibilities


ANALYTICAL SPECTROSCOPY 2020/2021
Computational Chemistry 2023/2024 2022/2023 2021/2022
COMPUTER IN SCIENCE 2019/2020 2018/2019
Final Year Project 1 2022/2023
FINAL YEAR PROJECT I 2022/2023 2021/2022 2020/2021
FINAL YEAR PROJECT II 2022/2023 2021/2022 2020/2021
Introduction to Practical Organic Chemistry 2023/2024 2022/2023 2021/2022 2020/2021
Medicinal Chemistry 2023/2024 2022/2023
MEDICINAL CHEMISTRY I 2021/2022 2020/2021 2019/2020 2018/2019
Organic Chemistry 1 2020/2021
ORGANIC CHEMISTRY I 2019/2020
ORGANIC CHEMISTRY II 2020/2021
Organic Reaction Mechanisms 2023/2024 2022/2023 2021/2022
Organic Synthesis 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020
PHYSICAL ORGANIC CHEMISTRY & REACTION MECHANISM 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019
SEPARATION TECHNIQUES FOR MEDICINAL CHEMISTRY 2019/2020


Supervision


Synthesis, Characterization, Biological Study And Molecular Docking Of Dithiocarbazate Derivatives And Their Metal Complexes.
Ph.D In Progress Co-supervisor
Novel In Silico Selex In Designing Aptamer Hairpin For In Vitro Detection Of He4: An Ovarian Cancer Biomarker.
Ph.D In Progress Co-supervisor
The Formulation Of 5-Fluorouracil-Loaded Hydrogel-Nanoparticles Hybrid For Treatment Of Oral Squamous Cell Carcinoma .
Master Completed 2023 Co-supervisor
Beta-Carboline Analogues With Improved Antibiotic Agent Towards Dna Gyrase: Molecular Design, Synthesis And Antibacterial Studies.
Master In Progress Main Supervisor
Design And Synthesis Of Xanthorrhizol Dervatives As Lipoxygenase And Hyaluronidase Inhibitors: In Silico And Inbitro Anaysis.
Master In Progress Co-supervisor


Research Projects


Completed
2019 - 2023 Assessment on suitable hydrocolloids for probiotic encapsulation enhancing its viablity and stability
2017 - 2022 Rheological and Physical Properties characterization of nanoparticles-hydrogel for topical oral drug of oral cancer (targeted drug delivery)
On-Going
2024 - Present Complete Genome Analysis of an Aquaculture Fish Pathogen Serotype III Streptococcus Agalactiae
2023 - Present Transferring of Knowledge to Industry and Community Through a Chrysotile Exposure Risk Prevention Program to Improve Workplace Safety & Health in the Vehicle Maintenance Workshop in Kuantan, Pahang.
2022 - Present Molecular design, SAR studies and mechanism of action of ?-Carboline analogues towards antibacterial infection: An in-silico approach
2021 - Present Hepatotoxicity Studies of Eltrombopag-Loaded PLGA_PEG polymeric Nanocapsules in ITP-Induced Mice Model
2019 - Present Preparation, characterisation and cytotoxicity assay of damnacanthal-loaded polymeric nanocapsules for breast cancer therapy
2017 - Present Formulation of 5-Fluorouracil-loaded EGFR-Targeted Hydrogel-Nanocapsule Hybrids for Oral Squamous Cell Carcinoma Therapy


Publications


Article

2023 Benzimidazole derivatives as potential neuraminidase inhibitors: conventional and microwave synthesis, in vitro and molecular docking analysis. Malaysian Journal of Analytical Sciences (MJAS), 27 (5) pp. 1003-1016
2023 Molecular docking and ADME profiles of β-Carboline analogues as potential antibiotic agents targeting DNA gyrase. Malaysian Journal of Chemistry, 25 (3) pp. 415-424
2023 Qualitative assessment the effect of glucose on hydrogel used for nanomedicine drug delivery. Revelation and Science, 13 (2) pp. 30-38
2023 Rheological assessments on alginate and carrageenan as nanoparticle carriers for topical oral cancer drug. Journal of Tropical Life Science, 13 (2) pp. 239-246
2023 Synthesis, Characterization, Antimicrobial activity and ADMET Analysis of S-benzyl-α-N-(anisoyl)-dithiocarbazate and its metal complexes. Malaysian Journal of Chemistry, 25 (3) pp. 481-491
2022 Molecular docking and adme profiling of xanthorrhizol derivatives as hyaluronidase inhibitors. Malaysian Journal of Chemistry, 24 (2) pp. 120-130
2022 Qualitative physical assessment on the effects of salt on potential hydrogels used in nanoparticle drug delivery. Revelation and Science, 12 (2) pp. 79-94
2021 Hydrogel-nanoparticle hybrids for biomedical applications: principles and advantages. Nanomedicine, 16 (2) pp. 81-84
2020 Hydrogel–nanoparticle hybrids for biomedical applications: principles and advantages. Nanomedicine, 16 (2) pp. 81-84
2017 Na+ entry through heteromeric TRPC4/C1 channels mediates (−)Englerin A-induced cytotoxicity in synovial sarcoma cells. Scientific Reports, 7 (1) pp.
2017 Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels. Journal of Biological Chemistry, 292 (20) pp. 8158-8173
2012 Ethyl 1-(2-hydroxyethyl)-2-[2-(methylsulfanyl)ethyl]-1H-benzimidazole-5-carboxylate. Acta Crystallographica Section E Structure Reports Online, 68 (1) pp. o197-o198
Conference or Workshop Item

2023 Design and synthesis of Xanthorrhizol derivatives using in silico fragment-based drug design (FBDD) approach as Hyaluronidase inhibitors. In: International Conference on Natural Products,
2023 Design of xanthorrhizol derivatives using in silico fragment-based drug design (FBDD) approach as lipoxygenase inhibitors. In: Postgraduate Colloquium 2023,
2023 Molecular docking and ADME profiles of β-carboline analogues as potential antibiotic agents targeting DNA gyrase. In: 3rd IKMPB Online Symposium 2023,
2022 Chessbot: a chemical safety and security telegram chatbot in Bahasa Malaysia. In: Kimia Invensi dan Inovasi Malaysia 2022,
2022 Design of xanthorrhizol derivatives using In silico fragment based drug design (FBDD) approach as Hyaluronidase Inhibitors. In: 3rd Commonwealth Chemistry Posters,
2022 Molecular docking and adme profiling of xanthorrhizol derivatives as hyaluronidase inhibitors. In: 2nd IKMPB Online Symposium,
Book Section

2023 Relevance of AI in microbased drug delivery system. In: Academic Press, an imprint of Elsevier, ISBN: 978-0-323-89925-3, pp. 123-143
2022 Nanotechnology-based approaches for antitubercular drug delivery. In: Elsevier, ISBN: , pp. 365-380