Staff Directory


Ridhwan Bin Abd Wahab @ Abdul Wahab

Academic Qualification

  • Doctor of Philosophy - Doctor of Philosophy, University Sains Malaysia
  • Master of Research (Bioinformatics) - Masters Degree, University of Leeds
  • Master of Science (Medical Science) - Masters Degree, Universiti Sains Malaysia (USM)
  • Bachelor of Science (Biomedical Science) (Honours) - Bachelor Degree, Nottingham Trent University
  • Diploma in Animal Health and Production - Diploma, Universiti Putra Malaysia (UPM)

Ridhwan Bin Abd Wahab @ Abdul Wahab (Assoc. Prof. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF ALLIED HEALTH SCIENCES


ridhwan@iium.edu.my
5262


Expert Profile


Presently, Dr Ridhwan is an Assistant Professor at the Department of Biomedical Sciences and Director of Integrated Centre for Research Animal, Care & Use (ICRACU), IIUM since 1st February 2012.


Teaching Responsibilities


ADVANCED IMMUNOLOGY 2014/2015 2020/2021 2017/2018 2021/2022 2013/2014 2015/2016 2019/2020
ADVANCED PHARMACOLOGY 2014/2015 2018/2019 2015/2016 2017/2018
BASIC IMMUNOLOGY 2015/2016 2013/2014 2017/2018 2019/2020 2018/2019 2020/2021
BASIC PATHOLOGY 2018/2019 2019/2020
BIOCHEMISTRY II 2011/2012
COMMUNITY SERVICE 2020/2021
DIAGNOSTIC MICROBIOLOGY 2020/2021
ENVIRONMENTAL MICROBIOLOGY 2020/2021 2018/2019
EPIDEMIOLOGY 2006/2007
ETHICS & LAW FOR HEALTH PROFESSIONALS 2017/2018 2018/2019 2019/2020
ETHICS AND LAW FOR HEALTH PROFESSIONALS 2021/2022 2020/2021
FAMILY MANAGEMENT AND PARENTING 2013/2014 2012/2013
FINAL YEAR RESEARCH PROJECT 1 2016/2017 2018/2019 2019/2020
FINAL YEAR RESEARCH PROJECT 2 2017/2018 2018/2019
FOOD MICROBIOLOGY 2006/2007
FOUNDATION MICROBIOLOGY 2006/2007 2007/2008
FUNCTIONAL BIOCHEMISTRY 2012/2013
HEALTH INFORMATICS 2013/2014 2014/2015 2015/2016 2012/2013 2016/2017
HEALTH INFORMATION SYSTEM 2006/2007
HEALTH MANAGEMENT AND HOSPITAL ADMINISTRATION 2006/2007
HEALTHCARE INFORMATION SYSTEM 2006/2007
HEALTHCARE MANAGEMENT AND ADMINISTRATION 2012/2013
HUMAN STRUCTURE & FUNCTION 2 2019/2020
IMMUNOLOGY 2012/2013 2013/2014
IMMUNOLOGY AND HAEMATOLGY LABORATORY PRACTICES 2020/2021 2019/2020
IMMUNOLOGY AND HAEMATOLOGY LABORATORY PRACTICES 2020/2021
INTRODUCTION TO BIOMEDICAL LABORATORY SCIENCES 2012/2013
ISLAMIC INPUT FOR HEALTH PROFESSIONAL 2019/2020
ISLAMIC INPUT FOR HEALTH PROFESSIONAL (MHSC) 2015/2016 2014/2015 2017/2018 2019/2020
ISLAMIC INPUT FOR HEALTH PROFESSIONALS 2017/2018
IT & HEALTH INFORMATICS 2017/2018 2019/2020 2020/2021 2018/2019
LEADERSHIP AND MANAGEMENT 2016/2017
MEDICAL MICROBE 2018/2019 2019/2020
MEDICAL MICROBIOLOGY 2017/2018 2013/2014 2020/2021 2012/2013
MICROBIOLOGY & IMMUNOLOGY 2012/2013 2013/2014 2016/2017 2014/2015
MICROBIOLOGY AND IMMUNOLOGY 2019/2020 2018/2019 2017/2018 2020/2021
MOLECULAR BIOLOGY & CYTOGENETIC TECHNIQUES 2017/2018 2018/2019 2014/2015 2015/2016
MOLECULAR BIOLOGY TECHNIQUES 2020/2021
MOLECULAR CANCER RESEARCH 2019/2020
NANOMEDICINE 2020/2021
NANOMEDICINE IN HEALTHCARE 2014/2015 2017/2018 2018/2019
NATURAL PRODUCT & HERBAL MEDICINE 2020/2021 2019/2020
PRINCIPLES OF MICROBIOLOGY 2012/2013 2020/2021 2014/2015 2017/2018 2019/2020 2015/2016 2016/2017 2018/2019 2013/2014
RESEARCH METHODOLOGY 2017/2018 2016/2017 2015/2016
RESEARCH METHODOLOGY (MHSC) 2015/2016 2016/2017
RESEARCH PROJECT 1 2020/2021
RESEARCH PROJECT 2 2020/2021
SPECIAL TOPICS IN BIOMEDICAL SCIENCE 2019/2020 2016/2017 2017/2018 2018/2019
SPECIAL TOPICS IN BIOMEDICAL SCIENCES 2019/2020 2020/2021


Research Projects


Completed
2020 - 2021 Elucidation on the Antimicrobial Property of Rosadiflora Species towards Human Pathogen
2018 - 2021 Elucidation of Candida albicans candidalysin mechanism in polymicrobial biofilms with Actinomyces naeslundii and Streptococcus mutans using flow cell model
2017 - 2019 The effect of polymicrobial interaction to the virulence factors of Candida albicans
2016 - 2018 Understanding of anti-cancer properties of Neolamarckia cadamba leaves on breast cancer: Prospective therapeutic Neolamarckia cadamba extracts
2016 - 2019 Understanding Anti-Angiogenesis Mechanism of Porcupine Bezoar Bioactive Compounds on Colon and Pancreas Cancer Cells Using Xenograft Zebrafish Model MyGrants : Understanding Anti-metastatic Mechanisms of Porcupine Bezoar Extract on Colon and Pancreas Cancer Cells Using in vitro Model
2015 - 2018 Evaluation of in vitro antihelmintic effect of crude leaves extracts of Piper betle (sireh) on gastrointestinal helminths obtained from goats
2015 - 2020 Evaluation of External Application of Halal Topical Cream of Neolamarckia Cadamba Leaves on Breast Cancer Cells in Rats Leading Towards Clinical Trial on Human Breast Cancer
2015 - 2019 Genomic Determinants Of Specific Virulent Gene Of Blastocystis Amoeboid Stage As A Marker In ZoonoticPotential, Biological And Host-Parasite Relationships
2014 - 2018 Identification of Specific Mirna Expression of Cryptosporidium in HCT-8 Cell and its Pathway as Fundamental Role in Pathogenesis Mechanisms
2013 - 2016 Understanding the Anti-Proliferative Mechanisms of Malaysian Porcupine Bezoar on Breast, Colon, Prostate and Tongue Cancer Cell Lines
2013 - 2018 Therapeutic Potential of Nypa Fruticans: Possible Alternative Antidiabetic Agent through Modulation of Key Gene Expression
On-Going
2021 - Present Determination of Anti-biofilm Property of Lactobacillus Rhamnosus towards Candida Albicans.
2020 - Present Prototype development of an organic and halal oral synbiotic (OroSYN) mouthwash containing Streptococcus salivarius and Pisang Emas skin extract.
2017 - Present Elucidating the anti-cancer Mechanism of thymoquinone nanoparticles involving the MAPK signaling pathway in zebrafish xenografts of colonic and melanoma cancers. in vitro & in vivo study
2015 - Present Upscale Production of the High Antioxidant Jelly Prepared from Baccaurea Angulata Fruit Enrich with Trigona Bee Honey for Head and Neck Patients
2013 - Present Identification of Dominantly Expressed Genes in Childhood Acute Lymphocytic Leukemia (ALL) in Malay Children
- Microbial Biotransformation of Terpenoids for the discovery of anticancer agents
- Microbial Biotransformation of Terpenoids for the discovery of anticancer agents


Publications


Article

2021 An in vitro anticancer activity evaluation of neolamarckia cadamba (Roxb.) bosser leaves’ extract and its metabolite profile. Frontiers in Pharmacology, 12 () pp. 1-11
2021 Epigenetic insights and potential modifiers as therapeutic targets in β–thalassemia. Biomolecules, 11 (5) pp. 1-20
2020 Determination toxic effects of Hystrix Brachyura Bezoar extracts using cancer cell lines and embryo zebrafish (Danio rerio) models and identification of active principles through GC-MS analysis. Journal of Ethnopharmacology, 262 () pp. 1-13
2020 In vitro antibacterial effect of the leaf extract of Murraya koenigii on cell membrane destruction against pathogenic bacteria and phenolic compounds identification. European Journal of Integrative Medicine, 33 () pp.
2020 The role of Candida albicans candidalysin ECE1 gene in oral carcinogenesis. Journal of Oral Pathology and Medicine, xx () pp. 1-7
2019 Anticancer activity of grassy Hystrix brachyura bezoar and its mechanisms of action: An in vitro and in vivo based study. Biomedicine & Pharmacotherapy, 114 () pp. 1-13
2019 Hystrix brachyura bezoar characterization, antioxidant activity screening, and anticancer activity on melanoma cells (A375): a preliminary study. Antioxidants, 8 (2) pp. 1-15
2019 Identification and quantification of quercetin, a major constituent of Artocarpus altilis by targeting related genes of apoptosis and cell cycle: in vitro cytotoxic activity against human lung carcinoma cell lines. Nutrition and Cancer, () pp. 1-14
2019 In-vitro cytotoxicity of Trigona itama honey against human lung adenocarcinoma epithelial cell line (A549). European Journal of Integrative Medicine, 30 () pp. 1-8
2019 Optimization of hyperglycemic induction in zebrafish and evaluation of its blood glucose level and metabolite fingerprint treated with psychotria malayana Jack Leaf extract. Molecules, 24 (8) pp. 1-22
2019 The effect of oral probiotic Streptococcus salivarius K12 on Candida albicans biofilm formation. IIUM Medical Journal Malaysia (IMJM), 18 (Supplementary Issue 2) pp.
2019 The promise of zebrafish as a model of metabolic syndrome. Experimental Animals, 68 (4) pp. 407-416
2019 Two-dimensional electrophoresis protein profiles of HL-60 and CCRF-CEM cell lines treated with epigenetic modification drugs. Asia-Pacific Journal Molecular Biology and Biotechnology, 27 (3) pp. 10-23
2018 A preliminary study for developing operator manual for ruminant abattoirs on prevention of foodborne diseases and halal compliance. International Journal of Allied Health Sciences, 2 (3) pp. 528-536
2018 Apoptotic induction in CCRF-CEM and HL-60 human leukemic cell lines by 5-Azacitidine and trichostatin A.. Journal of Biomedical and Clinical Sciences (JBCS), 3 (1) pp. 54-61
2018 Investigation on anti-proliferation properties of porcupine bezoar (hystrix brachyuran) extracts exposed on hela cells lines combined with electroporation technique. Journal of Telecommunication, Electronic and Computer Engineering, 10 (1-17) pp. 5-9
2018 Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines. South African Journal of Botany, 116 () pp. 16-24
2017 Cancer chemoprevention study of Luffa Aegyptiaca seed extract on human breast cancer cell lines (MCF-7). International Journal of Allied Health Sciences, 1 (1) pp. 13-13
2017 Cytotoxicity of leukemic cells by nypa fruticans through regulation of adiponectin expression. International Journal of Allied Health Sciences, 1 (2) pp. 28-43
2017 Expression of collagenases matrix metalloproteinases and YB-1 oncogenic factor in malignant melanoma cancer cells and its regulation by stromal fibroblasts. International Journal of Cancer Research, 13 (1) pp. 17-25
2017 In vitro evaluation of porcupine bezoar extracts as anticancer agent on A549 -A preliminary study. Advances in Biotechnology and Microbiology, 5 (1) pp. 1-8
2017 Occurrence of intestinal parasitic contamination in selected consumed local raw vegetables and fruits in Kuantan, Pahang. Tropical Life Sciences Research, 28 (1) pp. 23-32
2017 Understanding of anti-cancer properties of neolamarckia cadamba leaves extract on breast cancer cell. International Journal of Allied Health Sciences, 1 (1) pp. 20-20
2016 Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities. European Journal of Nutrition, 55 (4) pp. 1435-1444
2016 Identification of Cryptosporodium from Dairy Cattle in Pahang, Malaysia. Korean Journal of Parasitology, 54 (2) pp. 197-200
2016 Porcupine bezoar exhibit as anti-cancer activities on human breast adenocarcinoma cells (MCF-7). JOURNAL OF BIOMEDICAL AND CLINICAL SCIENCES, 1 (Special Issue) pp. 61-61
2015 Antioxidant activity and phenolic profile of various morphological parts of underutilised Baccaurea angulata fruit. Food Chemistry, 172 () pp. 778-787
2015 Evaluation of antioxidant, total phenol and flavonoid content and antimicrobial activities of artocarpus altilis (breadfruit) of underutilized tropical fruit extracts. Applied Biochemistry and Biotechnology, 175 (7) pp. 3231-3243
2015 The occurrence Cryptosporidium Oocysts in selected rivers and its physical assessments in Kuantan, Pahang. Journal of Applied Sciences Research, 11 (17) pp. 19-25
2015 The occurrence of cryptosporidium oocysts and physical assessment of selected lakes in Kuantan, Pahang. Journal of Applied Sciences Research, 11 (17) pp. 26-31
2014 Antimicrobial effect of Baccaurea angulata fruit extracts against human pathogenic microorganisms. Merit Research Journal of Medicine and Medical Sciences, 2 (10) pp. 229-237
2013 Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet. International Journal of Advances in Agricultural & Environmental Engineering (IJAEE), 1 (1) pp. 151-154
2013 In vitro antioxidant properties of underutilized baccaurea angulata fruit. International Journal of Advances in Agricultural & Environmental Engineering (IJAEE), 1 (1) pp. 144-150
Conference or Workshop Item

2019 Combined effect of Neolamarckia cdamba leaves and electroporation method on HeLa cell anti- proliferation process. In: 9th IEEE International Conference on Control System, Computing and Engineering (ICCSCE 2019),
2019 Influence of artocarpus altilis fruit extract on cancer cell. In: 9th IEEE Control and System Graduate Research Colloquium (ICSGRC 2018),
2019 Investigation of porcupine bezoar extract combined with electroporation on HeLa cell. In: 8th IEEE International Conference on Control System, Computing and Engineering, ICCSCE 2018,
2018 Artocarpus altilis extract effect on cervical cancer cells. In: INN International Conference/Workshop on “Nanotechnology and Nanomedicine (NTNM2017),
2018 In-vitro evaluation of porcupine bezoar extracts (PBE) as anti-cancer agent on HeLa cell line – A preliminary study. In: 3rd International Sciences, Technology & Engineering Conference (ISTEC) 2018 - Material Chemistry,
2018 Study of anti-cancer mechanism: Neolamarckia cadamba leaves exposed with electric field on HeLa cell. In: 7th IEEE International Conference on Control System, Computing and Engineering, ICCSCE 2017,
2017 Porcupine bezoar: in vitro antioxidant and anti-proliferative effects. In: 2nd International Anatomical and Biomedical Scientific Conference (IABS) 2017,
2016 Cancer chemoprevention study of luffa aegyptiaca (sponge gourd) seed extract on human breast cancer cell lines (MCF-7). In: 3rd Pan Asian Biomedical Science Conference 2016,
2016 Cryptosporidium in dairy cattle from a commercial farm Pahang. In: 52nd Annual Scientific Conference Malaysian Society of Parasitology and Tropical Medicine,
2016 Cryptosporidium in goats from different farming systems in Terengganu. In: 52nd Annual Scientific Conference Malaysian Society of Parasitology and Tropical Medicine,
2016 Porcupine bezoar exhibit cell cycle arrest through inhibiting cyclin /CDK1 complex and apoptosis mitochondria mediated dependent pathway in A549 cells. In: 3rd Pan-Asian Biomedical Science Conference 2016 (3rd PABSC),
2016 Prevalence of Cryptosporidium in goats in Terengganu. In: 52nd Annual Scientific Conference Malaysian Society of Parasitology and Tropical Medicine,
2016 Understanding of anti-cancer properties of Neolamarckia cadamba (Kalempayan) leaves extract on breast cancer cell. In: 3rd Pan-Asian Biomedical Science Conference 2016 (3rd PABSC),
2016 YB-1 gene expression in A375 malignant melanoma cells. In: 1st Allied Health Scientific Colloqium (AHSC 2016),
2015 Antileukemogenesis of nypa fruticans on acute lymphoblastic leukemia – a preliminary study in vitro. In: 2nd USIM International Conference on Medicine and Health (ICMH 2015),
2015 The occurrence of Cryptosporidium oocysts and physical assessment of selected lakes in Kuantan, Pahang. In: IPN-IWNEST 2015 Conferences,
2014 Antiatherosclerotic effect of Baccaurea angulate: an under-utilized fruit. In: K.A.H.S. Research Week 2014,
2014 Evaluation of antioxidant, total phenolsand flavonoids content and antimicrobial activities of Artocarpus altilis (breadfruit) of underutilized tropical fruit extracts. In: International Health Conference IIUM 2014,
2014 In vivo ctcf and yb-1 interaction with ap-1 site of matrix metalloproteinase 13 gene promoter in human malignant melanoma cell line. In: International Health Conference IIUM 2014,
2014 Potential hypocholesterolemic and health benefitsof Baccaurea angulata fruit in hypercholesterolemic rabbits. In: K.A.H.S. Research Week 2014,
Book Section

2020 The Buzzing "Moo". In: UPM Press, ISBN: 978-976-2395-74-7, pp. 13-20
2012 Apoptosis inducer from Streblus asper extracts for cancer chemoprevention. In: Springer , ISBN: 978-94-007-4916-0, pp. 1-25