Staff Directory


Widya Lestari

Academic Qualification

  • Ph.D (Molecular Biology) - Doctor of Philosophy, Tokyo Medical and Dental University
  • Master of Dental Science - Masters Degree, Universiti Malaya (UM)
  • Doctor of Dental Surgery - Bachelor Degree, Universitas Sumatera Utara

Widya Lestari (Assoc. Prof. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF DENTISTRY

Other's position:

Head, Research Management Centre


drwidya@iium.edu.my
2950


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Dentistry ~ Other Dentistry n.e.c. - DENTISTRY
  • Medical And Health ~ Medical And Health Sciences ~ Clinical Medicine ~ Oncology - ONCOLOGY
  • Medical And Health ~ Medical And Health Sciences ~ Dentistry ~ Other Dentistry n.e.c. - DENTISTRY


Teaching Responsibilities


CONSERVATIVE DENTISTRY YEAR 2 2019/2020
CONSERVATIVE DENTISTRY YEAR 3 2019/2020
Integrated Dental Practice 2019/2020 2020/2021 2013/2014
ORAL BIOLOGY 2019/2020 2015/2016 2020/2021 2013/2014 2017/2018 2018/2019 2014/2015
Research Project 2018/2019 2013/2014
RESEARCH YEAR 4 2018/2019 2020/2021 2019/2020


Research Projects


Completed
2018 - 2021 Polymorpysm with External Apical Root Resorption in Orthodontic Patients
2016 - 2019 Immunological, Histopathological and Gene Expression Changes Induced by Flax Seed Extract during Wound Healing Process
2016 - 2019 Molecular mechanisms of anticancer activity of Sarang Semut (Myrmecodia pendans) plant extract on oral squamous cell carcinoma cell line
2016 - 2019 Production and Quality Parameters of Halal Local Ingredients and Natural Products
2015 - 2019 Anti-Cariogenic Activity of Three Groups of Malaysian Seaweeds Extract Against Oral Cariogenic Bacteria: in Vitro
2015 - 2018 Clinical, Radiographic and genetic Evaluation of Non-Syndromic Hypodontia in Malaysia Population
2015 - 2020 Flax seed extract and its effect on WNT signaling pathway in the osteogenic differentiation potential of stem cells from human exfoliated deciduous teeth (SHED)
2013 - 2018 Production of Non-Thermally Processed Alternative Ingredients for Halal Food Products
2013 - 2021 Rapid Detection of Non-Halal Substances in Dental Materials
2013 - 2016 Study on the antioxidant activities of lutein and beta-carotene and their properties in cellular level.
On-Going
2021 - Present Elucidation of Contents in GOLDEN SPRAY ANTI-V
2021 - Present Evaluation of Antioxidant Activity of GOLDEN SPRAY ANTI-V
2021 - Present Evaluation of Anti-inflammatory property of Golden Spray Anti-V
2021 - Present Goniothalamus umbrosus. A potential chemo-preventive and anti-carcinogenic agent for oral squamous cell carcinoma
2019 - Present HIGH-RISK GENOTYPE HPV AND HSV-1 DETECTION ISOLATED FROM BUCCAL SWAB AND UNSTIMULATED SALIVA AND ITS ASSOCIATION WITH ORAL LESIONS AMONG TRANSGENDER PRACTISING HIGH RISK BEHAVIOUR IN MALAYSIA
2019 - Present Specific orthodontic tooth movement (OTM) biomarkers-related gene expression and hormonal changes induced by mechanical transduction on various mechanisms of orthodontic traction
2019 - Present STUDY ON THE PHYSICAL AND CHEMICAL CHARACTERISTICS OF SALIVA OBTAINED FROM SPECIAL NEEDS CHILDREN WITH CARIES
2019 - Present Development, Characterization and Invitro Study of Flax Seed Oil Ointment for Wound Healing
2019 - Present PHYSICOCHEMICAL CHARACTERIZATION, IN VITRO AND IN VIVO EVALUATIONS OF CHITOSAN ENRICHED WITH SEA CUCUMBER EXTRACT HYDROGEL AS DENTAL HAEMOSTATIC AGENT.
2019 - Present Empowering the Knowledge of Caretaker for Improvement of Oral Health Status of Children with Disabilities at Special Needs School in Kuantan
2015 - Present Comparative analysis of the sealing ability of various restorative materials used after endodontic treatment - a in vitro study
2013 - Present Therapeutic Effect of Sarang Semut Plant Extract (Myrmecodya Pendens) on Wound Healing in Oral Cavity


Publications


Article

2021 Determination of the fluoride content of Malaysian commercial teas. Scientific Dental Journal, 5 (3) pp. 68-73
2021 Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes. International Journal Of Oncology, 58 (4) pp. 1-12
2021 Effects of flaxseed (linum usitatissimum) extract on osteoblast differentiation potential of stem cells derived from human exfoliated deciduous teeth. Makara Journal of Health Research, 25 (1) pp. 1-7
2021 Halal aspect of dental materials. IIUM Journal of Orofacial and Health Sciences, 2 (2) pp. 67-68
2021 In vitro anti-cancer activities of luvunga scandens (‘Mengkurat Jakun’) on oral squamous cell carcinoma cells. Materials Science Forum, 1025 () pp. 191-196
2021 Systematic review of flaxseed (Linum usitatissimum L.) extract and formulation in wound healing. Journal of Pharmacy and Pharmacognosy Research, 10 (1) pp. 1-12
2021 The measurement of saliva and tongue coating pH in patients with physiological halitosis before and after using selected mouthwashes. Materials Science Forum, 1025 () pp. 197-203
2021 Tooth morphometry and pattern of palatal rugae among monozygotic twins in Malaysia. Journal of Orofacial Sciences, 13 (1) pp. 39-46
2020 A glimpse on the function of chitosan as a dental hemostatic agent. Japanese Dental Science Review, 56 () pp. 147-154
2020 Analysis of the anti-cancer effect of ethyl-p-methoxycinnamate extracted cekur (Kaempferia galanga) on cancer cell lines with wild-type and null p53. International Journal of Orofacial and Health Sciences, 1 (1) pp. 28-33
2020 Oral health related quality of life among transgender women in Malaysia. Journal of Critical Reviews, 7 (18) pp. 4624-4631
2020 PAX9 polymorphism in non-syndromic hypodontia in the Malaysian population. Journal of International Dental and Medical Research, 13 (3) pp. 1130-1135
2019 Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum. International Journal of Research in Pharmaceutical Sciences, 10 (4) pp. 2705-2710
2019 Gene expression of selected apoptotic markers in human oral squamous carcinoma HSC-3 cell line treated with Myrmecodia pendans plant extract. Makara Journal of Health Research, 23 (2) pp. 121-126
2019 Optimization and formulation of Fucoxanthin-Loaded Microsphere (F-LM) using Response Surface Methodology (RSM) and analysis of its fucoxanthin release profile. Molecules, 24 (5) pp. 1-16
2018 A review on non-syndromic tooth agenesis associated with PAX9 mutations. Japanese Dental Science Review, 54 (1) pp. 30-36
2018 Flaxseed ethanolic crude extract influences growth of stem cells from human exfoliated deciduous teeth (SHED). Journal of International Dental and Medical Research, 11 (2) pp. 643-649
2017 MSX1 and PAX9 genetic alteration in Malaysian families with hypodontia. Journal of International Dental and Medical Research, 10 (Spec issue) pp. 735-742
2017 Optimization of essential oil and fucoxanthin extraction from Sargassum binderi by Supercritical Carbon Dioxide (SC-CO2 ) extraction with ethanol as co-solvent Using Response Surface Methodology (RSM). International Food Research Journal, 24 (Suppl.) pp. S514-S521
2017 Screening of fatty acid compound of S. polycystum for anti-cariogenic potential. International Medical Journal Malaysia (IMJM), 16 (Supp. 2) pp. 1
2017 Some characteristics and functional properties of Chunma (Gastrodia elata) as a food supplement: a short review. International Food Research Journal (IFRJ), 24 (Suppl.) pp. S274-S280
2016 Analysis of TaeCheongsu natural water from Baegunsan Mountain, Korea. International Journal of Biotechnology and Bioengineering, 1 (1,02) pp. 14-19
2016 Effects of flaxseed extract on the viability of stem cells from human extracted deciduous teeth (SHED). Frontiers in Bioengineering and Biotechnology, () pp. 1-2
2016 Fabrication of Fucoxanthin-Loaded Microsphere ( F-LM) by two steps double-emulsion solvent evaporation methods and characterization of fucoxanthin before and after microencapsulation. Journal of Oleo Science, 65 (8) pp. 641-653
2016 Optimization of extraction process of plant-based gelatin replacer. International Food Research Journal, 23 (6) pp. 2519-2524
2016 PAX9 mutation of non-syndromic hypodontia in a Malaysian family. UI Proceedings on Health and Medicine, 1 () pp. 108-111
2015 Critical role of ARID3B in the expression of pro-apoptotic p53-target genes and apoptosis. Biochemical and Biophysical Research Communications, 468 (1-2) pp. 248-254
2012 Cooperation between ARID3A and p53 in the transcriptional activation of p21WAF1 in response to DNA damage. Biochemical and Biophysical Research Communications, 417 (2) pp. 710-716
Conference or Workshop Item

2020 Gene expression of selected apoptotic markers in human oral squamous carcinoma HSC-3 cell line treated with Myrmecodia pendans plant extract. In: The 11th Annual ISCC Conference and Congress (Virtual),
2020 The measurement of saliva and tongue coating pH in patients with physiological halitosis before and after using selected mouthwashes. In: 2nd Postgraduate Symposium in Industrial Science and Technology 2020,
2019 Anti-neoplastic potential of ethyl-p-methoxycinnamate of Kaempferia galanga on oral cancer cell lines. In: Conference on BioMedical and Advanced Materials (Bio-CAM 2017),
2019 Effects of flaxseed (Linum usitatissimum) extract on osteoblast differentiation potential of stem cells derived from human exfoliated deciduous teeth (SHED). In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019),
2019 Gene expression of selected apoptotic markers in HSC-3 treated with myrmecodia pendans plant extract. In: 11th National Dental Students Scientific Conference 2019,
2019 Gene expression of selected apoptotic markers in Human Oral Carcinoma (HSC-3) cell lines trewated with myrmecodia pendans plant extract. In: 8th Dental Students’ Scientific Conference IIUM 2019,
2019 Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines. In: Conference on BioMedical and Advanced Materials (Bio-CAM 2017),
2019 Prevalence, pattern and distribution of non-syndromic tooth agenesis in permanent dentition among Malaysian population. In: Conference on BioMedical and Advanced Materials (Bio-CAM 2017),
2019 The effect of flaxseed extract on genes expression during wound healing process in rabbit. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019),
2018 Apoptosis -inducing effects of aqueous myrmecodia pendans (sarang semut) extracts in HSC-3 human oral cancer cell lines: an-invitro study. In: 7th Dental Students Scientific Conference,
2018 Fluoride content determination in commercial teas in Malaysia. In: 7th Dental Students' Scientific Conference,
2018 Identification of MSX1 mutation in Malaysian hypodontia family. In: International Dental Conference of Sumatera Utara 2017 (IDCSU 2017),
2017 Comparative study: the repeatability of three diagnostic systems (laser fluorescence, visual (ICDAS II) and radiographic) for caries diagnosis. In: 6th IIUM Dental Students' Scientific Conference 2017,
2017 Determination of MSX1 genetic alteration in familial with hypodontia proband. In: 6th IIUM Dental Students' Scientific Conference 2017,
2017 Halalan toyyiban in dental materials. In: International Dental Conference Sumatera Utara 2017 (IDCSU) 2017,
2017 Non-syndromic tooth agenesis: pattern and distribution in permanent dentition among IIUM dental polyclinip Patients. In: 1st IIUM International Dental Conference,
2017 Rapid detection of gelatin in dental materials using attenuated total reflection fourier transform infrared spectroscopy (ATRFTIR). In: 1st Physics and Technologies in Medicine and Dentistry Symposium, PTMDS 2017,
2017 Screening of fatty acid compound of S. polycystum for anti-cariogenic potential. In: 1st IIUM International Dental Conference 2017 in Commemoration of the Kulliyyah of Dentistry 10th Anniversary (1st IIDC),
2017 Study on flaxseed crude extract on stem cells from human exfoliated deciduous teeth (SHED). In: 1st IIUM International Dental Conference 2017 in Commemoration of the Kulliyyah of Dentistry 10th Anniversary (1st IIDC),
2017 The repeatability of three diagnostic methods (visual using ICDAS II, laser fluorescence, and radiographic) for early caries detection. In: The 1st Physics and Technologies in Medicine and Dentistry Symposium,
2016 Effects of flaxseed extract on the viability of stem cells from human exfoliated deciduous teeth. In: 6th MTERMS (Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting) 2016 in conjunction with 2nd Malaysian Stem Cell Meeting,
2016 PAX9 mutation of non-syndromic hypodontia in a Malaysian family. In: 10th International Dentistry Scientific Meeting (IDSM) 2016,
2016 PAX9 mutation of non-syndromic hypodontia in three Malaysian families. In: 38th Asia Pacific Dental Congress (APDC 2016),
2015 Rapid detection of porcine and bovine gelatin in dental prophylaxis pastes using fourir transform infrared spectroscopy. In: MalaysiaiInternational Dental Exhibition and Conference 2015 (MIDEC 2015),
2015 Rapid detection of porcine and bovine gelatine in dental prophylaxis using fourir transform infrared spectroscopy. In: 7th National Dental Students' Scientific Conference (7th NDSSC) 2015,
2015 Rapid detection of porcine and bovine gelatins in dental prophylaxis pastes using fourier transform infrared spectroscopy . In: 4th Dental Student Scientific Conference,
2014 Dose-dependence of dietary antioxidants in their biological actions for research in human chronic diseases . In: International Research, Invention and Innovation Exhibition 2014 (IRIIE2014),
2014 New method for improving solubilization and uptake of lutein and carotenoids in human hepatocellular liver carcinoma (HepG2) cell culture . In: International Research, Invention and Innovation Exhibition 2014 (IRIIE2014),
2013 ARID3B silencing inhibits E2F-mediated transcription and cell proliferation. In: The 36th Annual Meeting of the Molecular Biology Society of Japan 2013,
2013 Cooperation between ARID3A and p53 in the transcriptional activation of p21WAF1 in response to DNA damage . In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2013,
Book Section

2021 Halal food ingredients: sources, classification and nutrition information. In: Yamani Angle Sdn Bhd, ISBN: 978-967-2199-21-2, pp. 19-35
2020 Camel gelatin composition, properties, production, and applications. In: IGI Global, ISBN: 9781799816041, pp. 306-327