Staff Directory


Wael Mohamed Yousef Mohamed

Academic Qualification

  • Doctor of Philosophy in Neuroscience - Doctor of Philosophy, Pennsylvania State University
  • MSc - Masters Degree, Menoufia University
  • MD - Bachelor Degree, Menoufia University

Wael Mohamed Yousef Mohamed (Assoc. Prof. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF MEDICINE


waelmohamed@iium.edu.my
4513


Expert Profile


-Translational brain research 
-Reverse translational brain research
-Human clinical trials
-Neurodegenerative disorders: AD & PD


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Neurosciences ~ Other Neurosciences n.e.c.


Teaching Responsibilities


BASIC PSYCHIATRY AND BASIC MEDICAL SCIENCES 2023/2024 2022/2023 2021/2022
BMS & GENERAL ORL-HNS ROTATION 2022/2023
BODY REACTION TO PHYSICAL, CHEMICAL & BIOLOGICAL AGENTS 2018/2019 2017/2018
BODY REACTIONS TO PHYSICAL, CHEMICAL AND BIOLOGICAL AGENTS 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020
Cardiovascular and Renal Systems Pharmacology 2023/2024
CARDIOVASCULAR, RESPIRATORY AND HAEMOPOIETIC SYSTEMS 2023/2024 2022/2023 2021/2022 2020/2021
CARDIOVASCULAR, RESPIRATORY, BLOOD AND BLOOD FORMING ORGANS 2019/2020 2018/2019
Central Nervous System Pharmacology 2023/2024
INTRODUCTION TO GENERAL PHARMACOLOGY 2020/2021
KNOWLEDGE AND SCIENCE IN ISLAM 2020/2021
NORMAL RESPONSE & PROCESS TO DISEASED STATE 2018/2019 2017/2018
NORMAL RESPONSE AND PROCESS TO DISEASED STATE 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020
NORMAL STRUCTURE & FUNCTION OF THE HUMAN CELL, TISSUE & BODY SYSTEM 2018/2019 2017/2018
NORMAL STRUCTURE & FUNCTION OF THE HUMAN CELL, TISSUE & BODY SYSTEMS 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020
STRUCTURE & FUNCTION IN NORMAL & DISEASED STATES & BEHAVIOURAL SCIENCE 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020
THE ALIMENTARY AND HEPATOBILIARY SYSTEMS 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018
THE ENDOCRINE, REPRODUCTIVE AND URINARY SYSTEMS 2023/2024 2022/2023 2021/2022 2020/2021
THE ENDOCRINE, REPRODUCTIVE URINARY SYSTEMS 2019/2020 2018/2019 2017/2018 2016/2017
THE LOCOMOTOR AND NERVOUS SYSTEMS 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018
USRAH IN ACTION 1 2022/2023
USRAH IN ACTION 2 2023/2024


Supervision


Neuroprotective Effect Of Thymoquinone (Tq) And Edible Bird Nest (Ebn) In Mptp Induced Parkinson’S Disease Zebrafish Model .
Ph.D In Progress Main Supervisor
Evaluation Of The Roles Imposed By Hmgb1 Protein In Mptp-Induced Zebrafish Model Of Parkinson'S Disease.
Ph.D In Progress Main Supervisor
Vancomycin Dosing In Critically Ill Patients With And Without Replacement Therapy.
Ph.D In Progress Co-supervisor
Neuroprotective Effects Of Combined Administration Of Coenzyme Q10 And Vitamin-E In Chronic Cerebral Hypoperfusion-Induced Neurodegeneration In Rats.
Master Completed 2019 Main Supervisor
Anti-Fertility Effect Of Fenugreek Seeds Aqueous Extract On Female Rats.
Master Completed 2017 Co-supervisor
In-Vivo Evaluation Of Acute Toxicity Of Trigonella Foenum-Graecaum Seeds Aqueous Extract On Renal Function And Histology Of The Kidney Using Female Rat Model.
Master Completed 2017 Co-supervisor
Neuroprotective Effects Of Edible Bird'S Nest In Chronic Cerebral Hypoperfusion-Induced Neurodegeneration In Rats.
Master Completed 2021 Co-supervisor


Research Projects


Completed
2021 - 2022 Exploring the Potential of Exosomal miRNA in Different Genetic Mutation as Potential Prognosis Biomarkers in Parkinson's Disease (PD)
2019 - 2023 Evaluation of the roles imposed by HMGB1 protein in MPTP-induced Parkinson Disease Zebra fish model
On-Going
2023 - Present AfrAbia-PD Genomic Consortium (AA-PDGC)
2021 - Present Fox Genetic Diversity in PD Program: Genome Wide Association (GWA) Study in Parkinson's Disease among East Asian
2018 - Present Effects of Edible Bird Nest on STZ induced Sporadic AD: A Rodent Model


Award & Recognition


14 Dec, 2023 Highest citation and highest publication indexed journal (Non-Clinical) - RMC-KOM National
14 Dec, 2023 MYRA 6 STAR 2022 - Others National
14 Oct, 2022 TOP 10 MYRA PERFORMANCE - TAKRIM DAY 2022 National
14 Oct, 2022 Best research team non-clinical - TAKRIM DAY 2022 National
14 Oct, 2022 Highest citation non-clinical - TAKRIM DAY 2022 National
12 Oct, 2019 Highest number of publications award indexed journal - TAKRIM DAY 2019 National


Publications


Article

2024 Brewing hopes: frequent drinking of tea or coffee significantly reduces the probability of getting Parkinson’s Disease. The Health, 7 (55) pp. 19-19
2024 The AfrAbia+plus Parkinson's disease genomic consortium. The Lancet Neurology, Vol 23 () pp. 140-141
2023 Academic dishonesty, plagiarism. The Health, 6 (47) pp. 11-11
2023 Author correction: Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2). npj Parkinson's Disease, () pp.
2023 Be ready to be a digital immigrant. The Health, 6 (51) pp. 19-19
2023 Bioactive strawberry fruit (Arbutus unedo L.) extract remedies paraquat-induced neurotoxicity in the offspring prenatally exposed rats. Frontiers in Neuroscience, 17 () pp. 1-15
2023 Coffee is a hug in a mug. The Health, 6 (45) pp. 24-24
2023 Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2). npj Parkinson's Disease, 9 () pp. 1-6
2023 Does your sleeping position matter?. Health Magazine Malaysia, 13 Feb 2023 () pp.
2023 Editorial: biomarkers in neurology, volume II. Frontiers in Neurology, 14 () pp. 1-3
2023 Editorial: neuroinflammation and neurodegeneration from bench to bedside. Frontiers in Neurology, 14 (1) pp. 1-3
2023 Editorial: translational neuroscience and reverse translational neuroscience: what's giving us hope?. Frontiers in Neuroscience, 17 () pp. 1-3
2023 Editorial: Zebrafish as a translational neuroscience model: today’s science and tomorrow’s success. Frontiers in Physiology, 14 () pp. 1-3
2023 High-mobility group box 1 (HMGB1) protein in Parkinson’s disease research: A 10-year bibliometric analysis. Journal of Integrative Neuroscience, 22 (4) pp. 1-8
2023 Identification of genetic risk loci and causal insights associated with Parkinson’s disease in African and African admixed populations: a genome-wide association study. The Lancet Neurology, () pp. 1-11
2023 Infertility and cortisol: a systematic review. Frontiers in Endocrinology, 14 () pp. 1-19
2023 Leveraging genetic diversity to understand monogenic Parkinson’s disease’s landscape in AfrAbia. American Journal of Neurodegenerative Disease, 12 (4) pp. 108-122
2023 Mitophagy: a bridge linking HMGB1 and Parkinson’s disease using adult zebrafish as a model organism. Brain Sciences, 13 (7) pp. 1-15
2023 Myelin healing: a paradigm shift. The Health Magazine Malaysia, 6 (49) pp.
2023 Nutrition and Parkinson's disease: what is the interplay?. Life Neuroscience (NeuroLife), 1 (1) pp. 24-30
2023 Parkinson’s genetics research on underrepresented AfrAbia populations: current state and future prospects. American Journal of Neurodegenerative Disease, 12 (2) pp. 23-41
2023 Precision medicine: a 'bed to bench to bed' approach. The Health, (June, 2023) pp. 18-18
2023 Precision medicine: data is the new gold. The Health, 6 (49) pp. 21-21
2023 Precision medicine: your sample, your world. The Health, 6 (50) pp. 20-20
2023 Role of AI in the digital medical workforce. The Health, 6 (53) pp. 21-21
2023 Single-cell RNA sequencing analysis and Alzheimer’s disease: a bibliometric analysis. American Journal of Neurodegenerative Disease, 12 (5) pp. 133-146
2023 Single-cell RNA sequencing analysis of human Alzheimer’s disease brain samples reveals neuronal and glial specific cells differential expression. PLOS ONE, () pp.
2023 Smartphone overuse as habit of pleasure seeking in Moroccan adults. Acta Neuropsychologica, 21 (2) pp. 139-146
2023 The effects of oral supplementation of Japanese sake yeast on anxiety, depressive-like symptoms, oxidative stress, and BDNF changes in chronically stressed adolescent rats. Life Neuroscience (NeuroLife), 1 (1) pp. 1-8
2023 When pixels cure more than pills!. The Health Magazine Malaysia, 20 Oct 2023 () pp.
2022 A case study of multiple sclerosis (MS). AfricArXiv Preprints, () pp.
2022 Alzheimer’s disease: an update and insights into pathophysiology. Frontiers in Aging Neuroscience, 14 () pp. 1-16
2022 Arab-Muslims contributions to modern neuroscience: what’s giving us hope?. AfricArXiv, () pp.
2022 Atypical antipsychotic Lumateperone beyond Schizophrenia: seeking clarity in a time of uncertainty. AfricarXiv, () pp.
2022 Characterization of neurobehavioral pattern in a zebrafish 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced model: a 96-hour behavioral study. PLOS ONE, () pp. 1-18
2022 Covid-19 and the central nervous system: what is the interplay?. Neuroscience Research Notes, 5 (4) pp. 1-21
2022 Crossing fingers and paws for Parkinson's disease. The Health, 5 (44) pp. 28-28
2022 Dance like no one's watching. The Health, 5 (38) pp. 26-26
2022 Development of a cognitive-based smartphone application for Malaysian Parkinson’s disease patients: exploring the possibility?. Neuroscience Research Notes, 5 (1) pp. 1-6
2022 Does Parkinson star in the nose. The Health, 5 (39) pp. 24-24
2022 Eating your way to good health. The Health, 14 October 2022 () pp. 24
2022 Edible bird nest as a potential cognitive enhancer. Frontiers Neurology, 13 () pp. 1-12
2022 Editorial: genes and aging: from bench-to-bedside. Frontiers in Aging Neuroscience, 14 () pp.
2022 Editorial: genetic and molecular diversity in Parkinson's disease. Frontiers in Aging Neuroscience, 14 () pp. 1-4
2022 Goofballing of Opioid and Methamphetamine: the science behind the deadly cocktail. Frontiers in Pharmacology, () pp.
2022 Integrating nutriepigenomics in Parkinson’s disease management: new promising strategy in the Omics era. IBRO Neuroscience Reports, () pp.
2022 Is sugar or fat worse?. The Health, July - August 2022 () pp.
2022 It is always possible to be kind. The Health, 20 September 2022 () pp. 21-21
2022 Leaving or living with Alzheimer's Disease. The Health, () pp. 24
2022 Neurodegeneration and inflammation crosstalk: therapeutic targets and perspectives. IBRO Neuroscience Reports, 14 () pp. 95-110
2022 Parkinson’s plus syndrome treatment: are we there yet?. IMJM, 21 (4) pp.
2022 Pharmacognosy and Parkinson’s disease prevention. The Health, 12 November 2022 () pp. 16-16
2022 Post Covid-19 symptoms among Covid-19 patients with comorbidities and non-comorbidities in Peninsular Malaysia. Journal of Science and Management Research, 9 (1) pp. 137-152
2022 The effects of oral supplementation of Japanese sake yeast on anxiety, depressive-like symptoms, oxidative stress, and BDNF changes in chronically stressed adolescent rats. bioRxiv, () pp.
2022 The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model. Neurochemistry International, 154 () pp.
2022 The glycoprotein GPNMB: a secret ingredient for understanding Parkinson's disease etiology?. Movement Disorders, () pp. 1-2
2022 The promise of Tele-Dementia: Today’s science and tomorrow’s trial. AfricArXiv Preprints, () pp.
2022 What is next in African neuroscience?. eLife, () pp. 1-7
2021 A child with fits: a case report for PBL. AfricArXiv Preprints, () pp.
2021 Accepting the unacceptable. The Health, November-December 2021 () pp. 36-36
2021 Atypical antipsychotic lumateperone effects on the adrenal gland with possible beneficial effect of quercetin co-administration. Frontiers in Physiology, 12 () pp. 1-15
2021 Burnout in academia the physiological effects of contagion and isolation go beyond fear of contracting the Covid-19 virus. The Health Malaysia, 4 () pp. 21-21
2021 Doses of reality. Health Magazine Malaysia, 4 (35) pp. 24-24
2021 Elevation of pro‑inflammatory and anti‑inflammatory cytokines in rat serum after acute methamphetamine treatment and traumatic brain injury. Journal of Molecular Neuroscience, () pp. 1-11
2021 Hormones in experimental autoimmune encephalomyelitis (EAE) animal models. Translational neuroscience, 12 () pp. 164-189
2021 Is an H-index of 13 shameful?: it is misleading to compare the research in African Arabian countries as they lack resources. The Health Malaysia, 4 (31) pp. 21
2021 Medroxyprogesterone acetate attenuates demyelination, modulating microglia activation in a cuprizone neurotoxic demyelinating mouse model. American Journal of Neurodegenerative Disease, 10 (5) pp. 57-68
2021 Metformin therapy attenuates pro-inflammatory Microglia by inhibiting NF-κB in cuprizone demyelinating mouse model of multiple Sclerosis. Neurotoxi Research, 39 () pp. 1732-1746
2021 Neuroprotective effect of edible bird’s nest in chronic cerebral hypoperfusion induced neurodegeneration in rats. Neuroimmunology and Neuroinflammation, 8 () pp.
2021 Neurotoxin‑induced rodent models of Parkinson’s disease: benefits and drawbacks. Neurotoxicity Research, 39 (3) pp. 897-923
2021 The price of research collaboration be careful who you co-work with on projects as it may end up with a lot of heartache. The health Malaysia, 4 (32) pp. 21-21
2021 The East Asian Parkinson disease genomics consortium. The Lancet Neurology, 20 (12) pp. 982
2021 The promise of the Zebrafish model for Parkinson’s disease: today’s science and tomorrow’s treatment. Frontiers In Genetics, 12 () pp. 1-17
2020 Editorial: biomarkers in neurology. Frontiers in Neurology, 11 () pp. 1-3
2020 Editorial: contribution of translational animal models to the systems biology of neurodegenerative disorders. Frontiers in physiology, () pp. 1-3
2020 Integrated neural technologies: solutions beyond tomorrow. Neuroscience research notes, 3 (5) pp. 1-3
2020 Neuroprotective effects of co-administration of Coenzyme Q10 and vitamin-E in chronic cerebral hypoperfusion-induced neurodegeneration in rats. International Journal of Nutrition, Pharmacology, Neurological Diseases, 10 (2 (April-June)) pp. 35-42
2020 Pharmacotherapy of alzheimer’s disease: seeking clarity in a time of uncertainty. Frontiers in Pharmacology, 11 () pp. 1-16
2019 Depression following major life transitions in women: a review and theory. Psychological Reports, () pp. 1-17
2019 FOXRED1 silencing in mice: a possible animal model for leigh syndrome.. Metabolic Brain Disease, 34 (1) pp. 367-372
2019 siRNA blocking of mammalian target of rapamycin (mTOR) attenuates pathology in annonacin-induced tauopathy in mice. Neurotoxicity Research, 35 (4) pp. 987-992
2018 C-Abl inhibition; a novel therapeutic target for Parkinson’s disease. CNS & Neurological disorders-Drug targets, 17 (1) pp. 14-21
2018 Dual mTORC1/mTORC2 blocker as a possible therapy for tauopathy in cellular model. Metabolic Brain Disorder, 33 (2) pp. 583-587
2018 Light-Emitting Diode (LED) therapy attenuates neurotoxicity of methanol-induced memory impairment and apoptosis in the hippocampus. CNS Neurol Disord Drug Targets, 17 (7) pp. 528-538
2018 Mechanisms of disordered neurodegenerative function: concepts and facts about the different roles of the protein kinase RNA-like endoplasmic reticulum kinase (PERK). Reviews in the Neurosciences, 29 (4) pp. 387-415
2018 Neuroprotective effect of oral administration of Trigonella Foenum-Graecum on chronic cerebral hypoperfusion in rat model. International Medical Journal Malaysia, 17 (Supplementary Issue 1) pp. 48-48
2018 Oxidative stress status and neuroprotection of tocotrienols in chronic cerebral hypoperfusion-induced neurodegeneration rat animal model. International Journal of Nutrition, Pharmacology, Neurological Diseases, 8 (2) pp. 47-52
2018 Tubulin and tau: Possible targets for diagnosis of Parkinson’s and Alzheimer’s diseases. PLoS ONE, 13 (5) pp.
2017 Effect of intranasal stem cell administration on the nigrostriatal system in a mouse model of Parkinson's disease. Experimental and Therapeutic Medicine, 13 (3) pp. 976-982
2017 Elevated serum α-synuclein autoantibodies in patients with Parkinson’s disease relative to Alzheimer’s disease and controls. Frontiers in Neurology, 8 () pp. 1-6
2017 Genetic underpinnings in Alzheimer’s disease – A review. Reviews in the Neurosciences, 29 (1) pp. 21-38
2017 Interactions between cannabis and schizophrenia in humans and rodents. Reviews in the Neurosciences, 28 (7) pp. 811-823
2017 Thyroxine (T4) transfer from blood to cerebrospinal fluid in sheep isolated perfused choroid plexus: role of multidrug resistance-associated Proteins and Organic anion Transporting Polypeptides. Frontier in Neurology, 8 () pp. 1-10
2016 Familiarity, perception, and reasons for electronic‑cigarette experimentation among the general public in Malaysia: Preliminary insight. Journal of Pharmacy and Bioallied Sciences, 8 (3) pp. 240-247
2016 Tau protein as a biomarker for asphyxia: a possible forensic tool?. Applied and Translational Genomics, 9 () pp. 20-22
2016 The relationship between duration of infertility and intrauterine insemination: a multi-centers study. Journal of Clinical Developmental Biology, 1 (3) pp. 3-13
2015 Investigation of redox status in chronic cerebral hypoperfusion-induced neurodegeneration in rats. Applied & Translational Genomics, 5 (1) pp. 30-32
Conference or Workshop Item

2021 Neuroprotective effect of edible bird’s nest in chronic cerebral hypoperfusion-induced neurodegeneration in rats. In: 7th Asian-Oceanian Congress on Clinical Neurophysiology,
2020 Alzheimer's disease: from bench side to bed side. In: Hi-5 Retreat 2020: V-Symposium Basic Neuroscience Council (BNC),
2018 Biomarkers in AD: current state of translational research. In: 32nd Scientific Meeting of Malaysian Society of Pharmacology & Physiology,
Book

2023 Biomarkers in neurology, volume II. Frontiers, ISBN: 978-2-8325-3105-1
2023 Trace elements in brain health and diseases. Springer, ISBN: 978-981-99-1512-5
2022 Brain-iron cross talk. Springer Nature, ISBN: 978-981-19-7326-0
2022 Genes and aging: from bench side to bed side. Frontier, ISBN: 978-2-88974-974-4
2022 Nutrition and Psychiatric Disorders. Springer Singapore, ISBN: 978-981-19-5020-9
2022 Role of micronutrients in brain health. Springer Nature, ISBN: 978-981-16-6466-3
2020 Biomarkers in neurology. Frontier, ISBN:
Book Section

2023 Edible bird’s nest: seeing the unseen. In: Springer Singapore, ISBN: 978-981-99-1512-5, pp. 15-45
2023 Nutrigenomics and trace elements: hopes and hypes for Parkinson’s Treatment. In: Springer Singapore, ISBN: 978-981-99-1512-5, pp. 47-69
2022 Impact of a psychological follow-up of diabetics in the management of diabetes in Morocco. In: Springer, ISBN: 978-981-16-8157-8, pp. 115-124
2022 Neuroprotective and anxiolytic effects of date seeds phenolic compounds in nicotinamide-streptozotocin-induced Type 2 diabetic rats. In: Springer, ISBN: 978-981-16-8157-8, pp. 125-142
2019 Animal model for leigh syndrome. In: Humana Press, ISBN: 978-1-4939-9553-0, pp. 451-466