Staff Directory


Sirajudeen Kuttulebbai Naina Mohamed Salam

Academic Qualification

  • Doctor of Philosophy in Biochemistry - Doctor of Philosophy, University of Madras
  • Master of Science - Masters Degree, Bharathidasan University
  • Master of Science - Masters Degree, University of Madras
  • Master of Philosophy - Masters Degree, University of Madras
  • Bachelor of Science - Bachelor Degree, Bharathidasan University

Sirajudeen Kuttulebbai Naina Mohamed Salam (Prof. Dr.)

Professor
IIUM Kuantan Campus

KULLIYYAH OF MEDICINE

Other's position:

Head, Kulliyyah of Medicine


knssiraj@iium.edu.my
4490


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Medical Biochemistry and Clinical Chemistry ~ Antioxidants - oxidative stress and antioxidants in hypertension
  • Medical And Health ~ Medical And Health Sciences ~ Complementary/Alternative Medicine ~ Traditional Medicine and Natural Product (Including Development of Traditional and Herbal Medicine) - Role of honey in experimental models of hypertension, diabetes and excitotoxicity
  • Medical And Health ~ Medical And Health Sciences ~ Biomedical Sciences ~ Other Biomedical Sciences n.e.c. - Honey and natural products in wound healing in animal models
  • Medical And Health ~ Medical And Health Sciences ~ Medical Biochemistry and Clinical Chemistry ~ Lipids - Biochemical toxicology and pharmacology


Professional Membership


  • 2001 - 2020: Member of Profesional Body / Association: (Member), Kelantan Indian Muslim Association
  • 2003 - 2020: Member of Profesional Body / Association: (Member), Malaysian Association of Clinical Biochemists
  • 2011 - 2020: Member of Profesional Body / Association: (Life member), Society of Free Radical Research, India.
  • 2012 - 2020: Member of Profesional Body / Association: (member), Malaysian Natural Products Society
  • 2015 - 2020: Member of Profesional Body / Association: (Life Member), Indian Academy of Biomedical Sciences
  • 2017 - 2020: Member of Profesional Body / Association: (Life Member), Malaysian Society of Pharmacology and Physiology
  • 2020 - 2020: Member of Profesional Body / Association: (Affiliated member), Malaysian society of Neurosciences


Teaching Responsibilities


BASIC GENETICS OF HUMAN DISEASE 2020/2021 2019/2020
BASIC LABORATORY TECHNIQUES 2019/2020
BODY REACTIONS TO PHYSICAL, CHEMICAL AND BIOLOGICAL AGENTS 2021/2022 2020/2021 2019/2020
CARDIOVASCULAR, RESPIRATORY AND HAEMOPOIETIC SYSTEMS 2022/2023 2021/2022 2020/2021
CARDIOVASCULAR, RESPIRATORY, BLOOD AND BLOOD FORMING ORGANS 2019/2020
General Laboratory Techniques and Instrumentations 2022/2023 2021/2022
INTRODUCTION TO MEDICAL BIOCHEMISTRY 2019/2020
MEDICAL ENZYMOLOGY 2019/2020
MEDICAL LABORATORY INSTRUMENTATION 2019/2020
NORMAL RESPONSE AND PROCESS TO DISEASED STATE 2022/2023 2021/2022 2020/2021 2019/2020
NORMAL STRUCTURE & FUNCTION OF THE HUMAN CELL, TISSUE & BODY SYSTEMS 2022/2023 2021/2022 2020/2021 2019/2020
REGULATION OF METABOLISM IN HUMAN 2019/2020
STRUCTURE & FUNCTION IN NORMAL & DISEASED STATES & BEHAVIOURAL SCIENCE 2021/2022 2020/2021 2019/2020
THE ALIMENTARY AND HEPATOBILIARY SYSTEMS 2022/2023 2021/2022 2020/2021 2019/2020
THE ENDOCRINE, REPRODUCTIVE AND URINARY SYSTEMS 2021/2022 2020/2021
THE ENDOCRINE, REPRODUCTIVE URINARY SYSTEMS 2019/2020
THE LOCOMOTOR AND NERVOUS SYSTEMS 2021/2022 2020/2021 2019/2020


Research Projects


Completed
No data
On-Going
2022 - Present Elucidating the Role of Alpha-1-Antitrypsin, Inflammation and Oxidative Stress in the Pathogenesis and Disease Progression of COVID-19 Positive Cases
2022 - Present Understanding the antioxidant and anti-inflammatory role of tualang honey in weight reduction and changes to gut microbiota in diet-induced obese rats.
2020 - Present Effect of Pharmaco Mechanism(s) of Action of Bitter Guard Honey in Streptozotocin Induced Type II Diabetic Rats
2020 - Present Understanding and Elucidating the Cellular Mechanism of Oral and Topical Administration of Stingless Bee Honey (SBH) in Promoting Wound Healing in Streptozotocin-Induced Diabetic Rat Wound Models
2020 - Present Tualang Honey Silver Nanoparticle: Extending its Anti-Oxidative, Anti-Inflammatory Role in Kainite Induced Neurodegeneration in Rat Hippocampus
2020 - Present Understanding the Effect of Vitamin A (Retinoic Acid) on Liver Histopathological and Ultrastructural Changes in High Cholesterol Diet Induced Rat?s Steatosis.
2020 - Present Elucidation of Chemical Structure and Wound Healing Properties of B-Glucan Produced from a Newly Isolated Excessive B-Glucan Producing Proteus Mirabilis Strain
2020 - Present Understanding the Inflammatory and Molecular Mechanism of Chronic Kidney Disease Patients with Chronic Periodontitis
2020 - Present Elucidating the Involvement of Toll-like Receptors in the Mediation of Anxiety Behaviour of Rats
2020 - Present Understanding the Role of Glycemic Control Factors in Modulating Genetic VDR Polymorphism among Type 2 Diabetes Patients
2020 - Present Effect of Vitamin A (retinoic acid) on serum, liver biochemical parameters and diacylglycerol acyltransferase 2 (DGAT2) expression in High Cholesterol Diet-Induced Rat's Steatosis
2020 - Present Neuroprotection of Omega-3 Fatty Acid and Tualang Honey Supplimentation Following Exposure to Chronic Stress in Rat Model


Award & Recognition


04 Aug, 2022 BEST PROJECT - Universiti Teknologi Malaysia (UTM) National
01 Jul, 2022 TAKRIM DAY 2022, KOM award for Highest publication in indexed journal (non-clinical) - Kulliyyah of Medicine, IIUM KCDIO
24 Jun, 2022 Best Poster Award - College of Pathologists, Academy of Medicine Malaysia National
24 Nov, 2021 Silver Award: Preliminary study on the effects of tualang honey and its silver nanoparticles on kainic acid mediated hippocampal excitotoxicity and memory impairments in male rats IIUM Research Day 2021 - International Islamic University Malaysia University


Publications


Article

2022 Bioactivity and pharmacological potential of date palm (phoenix dactylifera L.) against Pandemic COVID‑19: a comprehensive review. Applied Biochemistry and Biotechnology, 194 () pp. 4587-4624
2022 DHA-rich fish oil and Tualang honey reduce chronic stress-induced oxidative damage in the brain of rat model. Journal of Traditional and Complementary Medicine, 12 (4) pp. 361-366
2022 Effect of Acacia honey drink consumed pre and during exercise on glucose metabolism, total antioxidant status, and running performance in the heat. IIUM Medical Journal Malaysia, 21 (3) pp. 85-95
2022 Profiling the research landscape on cognitive aging: a bibliometric analysis and network visualization. Frontiers in Aging Neuroscience, 14 () pp. 1-12
2022 Review: ischemic heart disease and the potential role of fenugreek (trigonella foenum graecum linn.) In cardioprotection. Jurnal Teknologi, 84 (2) pp. 183-197
2022 Silver nanoparticles synthesized using Tualang honey ameliorate seizures, locomotor activity, and memory function in KA-induced status epilepticus in male rats. Biomedical Research and Therapy, 9 (9) pp. 5291-5300
2021 A preliminary study on the effects of Stingless Bee Honey (SBH) on fasting blood glucose in Streptozotocin (STZ)-Induced diabetic rat models. Malaysian Applied Biology, 50 (2) pp. 151-156
2021 Association between vitamin D receptor polymorphisms (BsmI and FokI) and glycemic control among aatients with type 2 diabetes. International Journal of Environmental Research and Public Health, 18 (4) pp. 1-18
2021 Bitter gourd honey ameliorates hepatic and renal diabetic complications on type 2 diabetes rat models by antioxidant, anti-Inflammatory, and anti-apoptotic mechanisms. Foods, 10 (11) pp.
2021 Effects of prolonged running under different environmental conditions on selected physiological markers, muscle damage and time–trial performance in recreational athletes. Journal of Physical Education and Sport, 21 (4) pp. 2289-2296
2021 Inhibition of cystathionine-γ-lyase-mediated hydrogen sulfide production in LPS-stimulated RAW 264.7 macrophages by polyherbal extract. Indian Journal of Experimental Biology, 59 () pp. 111-117
2021 Levels of interleukins in patients with chronic kidney disease and periodontitis: a systematic review. Journal of International Oral Health, 13 (4) pp. 313-318
2021 Quantitative description of publications (1986-2020) related to Alzheimer disease and oxidative stress: a bibliometric study. Journal of Cellular Neuroscience and Oxidative Stress, 13 (1) pp. 971-984
2021 The effect of retinoic acid on non-alcoholic fatty liver disease (NAFLD) model. IIUM Journal of Orofacial and Health Sciences, 3 (Supplement 1) pp. 36
2020 A review on oxidative stress, diabetic complications, and the roles of honey polyphenols. Oxidative Medicine and Cellular Longevity, 2020 () pp. 1-16
2020 Assessment and comparison of the effect of oral Channa striatus extract versus glucosamine sulphate administration in serum cartilage and inflammatory marker in knee osteoarthritis patients. Malaysian Journal of Medical Sciences, 27 (Special Issue) pp. 28-29
2020 Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women. International Medical Journal, 27 (2) pp. 148-150
2020 Effects of DHA and Tualang honey on the brain cytokines following chronic stress exposure in rat model. Malaysian Journal of Medical Sciences, 27 (Special Issue) pp. 24-25
2020 Evaluation of wound healing biomarkers of Interleukin 6 (IL-6), Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases 9 (MMP-9) in post Lower Segment Caesarean Section (LSCS) patients consuming Channa Striatus extract. Bangladesh Journal of Medical Science, 19 (3) pp. 520-526
2020 Green synthesis and characterization of silver nanoparticles using Tualang honey and evaluation of their antioxidant activities.. Advances in Natural Sciences: Nanoscience and Nanotechnology, 11 (2) pp. 1-7
2020 Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases. Evidence-Based Complementary and Alternative Medicine, 2020 () pp. 1-30
2020 Preliminary study on the effect of Tualang honey and its silver nanoparticles on Kainic acid mediated behavioural changes in male rats. Malaysian Journal of Medical Sciences, 27 (Special Issue) pp. 18-19
2020 Prevalence of metabolic syndrome associated factors in the adult in UAE: effect of gender and age. Obesity, 28 (Supplement 2) pp. 142-143
2019 Effect of alpha-lipoic acid supplementation on blood pressure, renal oxidant-antioxidant status and renal damage in spontaneously hypertensive rats. Asian Pacific Journal Tropical Biomedicine, 9 (10) pp. 415-423
2019 Evaluation of chondroprotective activity of Channa striatus in rabbit osteoarthritis model. BioMed Research International, 2019 () pp. 1-11
2019 Keladi candik (Alocasia longiloba Miq.) petiole extracts promote wound healing in a full thickness excision wound model in rats. Asian Pacific Journal of Tropical Biomedicine, 9 (4) pp. 140
2019 LPS-induced apoptosis is partially mediated by hydrogen sulphide in RAW 264.7 murine macrophages. Immunological Investigations, 48 (5) pp. 451-465
2019 Medicinal bioactive compounds to functional foods from geochemical signatures marine biomasses: sea cucumbers, macroalgae and crown of thorns biomasses. Life Sciences, Medicine and Biomedicine, 3 (5) pp. 1-9
2019 Novel phytochemical constituents and anticancer activities of the Genus, Typhonium. Current Drug Metabolism, 20 (12) pp. 946-957
2019 Tualang honey and DHA-rich fish oil reduce the production of pro-inflammatory cytokines in the rat brain following exposure to chronic stress. Journal of Taibah University Medical Sciences, 14 (4) pp. 317-323
Conference or Workshop Item

2022 Role of honey and its chemical constituents on Neuroprotection. In: 2nd International Conference on “Global Trends in Applied Sciences, Medical and Health Sciences (ICGTAMH-2022),
2021 Preliminary study on the effect of Tualang Honey and its silver nanoparticles on Kainic Acid-Induced memory deficits and oxidative damage in rat hippocampus. In: 4th Kuantan Research Day 2020,
2020 Antioxidants and brain interplay. In: International Webinar On Nutritional, Brain and Behaviour,
2020 Biochemistry: carbohydrates, fat, protein and iron metabolism. In: Prepartory Course for the Medical Specialists Pre-Entrance Examination (Medx O&G),
2020 Diabetes mellitus, oxidative stress & antioxidants. In: Refresher Course for Young Academic Staff In Health Management By UGC-HRDC, S V University, India,
2020 The association of serum adipokines and vitamin D level in newly diagnosed women with breast cancer: a case-control study. In: 35th Nutrition Society of Malaysia (NSM) Scientific Conference,
2020 Tualang honey action on experimentally induced excitotoxicity. In: International E-Conference on New Horizons in Biochemistry, Microbiology and Food Technology - 2020,
2020 Tualang honey: role in experimental diabetes mellitus. In: The International Virtual Conference on Diabetes 2020,
2019 The value of geochemical signatures marine by-products, with highlights from taxonomies sea cucumbers, macroalgae and crown of thorns starfish. In: 6th International Conference on Environment: Empowering Environment and Sustainable Engineering Nexus Through Green Technology, ICENV 2019,
Book

2017 Paraoxonase activity in healthy population of major ethnic groups. IIUM Press, International Islamic University Malaysia, ISBN: 978-967-418-730-9