Staff Directory
Academic Qualifications
- Ph.D in Human Germ Cell Development & Spermatogenesis Form Stem Cells - Doctor of Philosophy, University of Sheffield
- Pharmacy - Masters Degree, Universiti Kebangsaan Malaysia (UKM)
- Biomedical Science - Bachelor Degree, Universiti Kebangsaan Malaysia (UKM)
Muhammad Lokman Bin Md. Isa (Prof. Dr.)
Professor
IIUM Kuantan Campus
INSTITUTE OF PLANETARY SURVIVAL FOR SUSTAINABLE WELLBEING
Other's position:
Director, Institute of Planetary Survival for Sustainable Wellbeing
lokman@iium.edu.my
7206
Expert Profile
Prof. Ts. Dr. Muhammad Lokman Md Isa achieved his Doctorate in Philosophy from The University of Sheffield, specialising in Human Germ Cell Development & Spermatogenesis Form Stem Cells. Prior to this, he pursued his undergraduate and postgraduate studies at Universiti Kebangsaan Malaysia (UKM), majoring in Biomedical Science and Health Science respectively. With a focus on molecular and cellular technology and reproductive stem cells, his academic journey at the International Islamic University Malaysia (IIUM) has been marked by diverse research endeavors spanning human, animal, and plant biology. Presently, Dr. Muhammad Lokman's research endeavors are centered around planetary health, a collaborative effort involving academia, government, private sector, community, and environmental stakeholders. Notably, his groundbreaking achievement lies in establishing the Frozen Zoo, the first of its kind in Southeast Asia, and fostering regional networks for the same purpose. The Frozen Zoo at IIUM serves as a repository for cell lines and biological samples from endangered species, offering innovative solutions to combat wildlife extinction driven by climate change. His expertise extends to serving as a member of the expert working group on endangered wildlife species (EWG EWS), further underscoring his commitment to conservation efforts.
Area of Specialisation
- Medical And Health ~ Medical And Health Sciences ~ Pharmacology ~ Medical Pharmacology - Basic pharmacology (Pharmacokinetic and Pharmaco dinamic)
- Natural Science ~ Biological Sciences ~ Genetics ~ Molecular Genetics - Cell interaction 1) Human reproductive hormones study
- Biotechnology ~ Biotechnology ~ Medical Biotechnology ~ Stem Cell Technology - Human Gem Cell Development & Spermatogenesis from Stem Cells,Regenerative medicine-Stem cell and Andrology study; Human Gem Cell Development & Spermatogenesis from Stem Cells
- Medical And Health ~ Medical And Health Sciences ~ Phamaceutical Industry ~ Other Pharmaceutical Industry n.e.c. - Lipid emulsion technology, intravenous lipid emulsion
Teaching Responsibilities
| ANATOMY, PHYSIOLOGY AND BIOCHEMISTRY I | 2019/2020 2018/2019 2017/2018 |
| ANATOMY,PHYSIOLOGY AND BIOCHEMISTRY II | 2019/2020 2018/2019 2017/2018 |
| BIOCHEMISTRY FOR NURSING | 2020/2021 |
| COMMUNITY SERVICE 1 | 2018/2019 |
| COMMUNITY SERVICE 2 | 2019/2020 |
| DISCOVERY OF SPECIALIZATION IN NURSING | 2019/2020 |
| ENTERPRENUERSHIP IN NURSING | 2019/2020 |
| FINAL YEAR RESEARCH PROJECT I | 2022/2023 2021/2022 2020/2021 2019/2020 |
| FINAL YEAR RESEARCH PROJECT II | 2022/2023 2021/2022 2020/2021 2019/2020 |
| GENERAL PATHOLOGY | 2021/2022 2020/2021 |
| GENERAL PATHOLOGY AND INFECTIOUS AGENT | 2016/2017 |
| GENERAL PATHOLOGY AND INFECTIOUS AGENTS | 2018/2019 2017/2018 |
| INNOVATION IN NURSING | 2021/2022 2020/2021 2019/2020 2018/2019 |
| INTEGRATED NURSING SCIENCES | 2016/2017 |
| INTEGRATED NURSING SCIENCES (FINAL PROFESSIONAL EXAMINATION) | 2018/2019 2017/2018 |
| LEADERSHIP AND MANAGEMENT | 2018/2019 2017/2018 |
| MICROBIOLOGY, IMMUNOLOGY AND PARASITOLOGY | 2021/2022 2020/2021 |
| PATHOLOGY AND HUMAN GENETIC | 2016/2017 |
| PHARMACOLOGY | 2019/2020 2018/2019 2017/2018 2016/2017 |
| RESEARCH PROJECT FINAL | 2018/2019 2017/2018 2016/2017 |
| RESEARCH PROJECT PROPOSAL | 2018/2019 2017/2018 |
| SUSTAINABLE DEVELOPMENT: ISSUES, POLICIES AND PRACTICES | 2020/2021 |
| SUSTAINABLE DEVELOPMENT: ISSUES, PRINCIPLES AND PRACTICES | 2024/2025 2023/2024 |
| SYSTEMIC PHARMACOLOGY | 2021/2022 |
| USRAH IN ACTION 1 | 2024/2025 2023/2024 2022/2023 |
| USRAH IN ACTION 2 | 2025/2026 2024/2025 2023/2024 |
Supervision
|
Horseshoe Crab Tachypleus Gigas Migration Route And Landing Preferences In Balok River Pahang.
Ph.D
Completed
2024
Co-supervisor
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Analyzing Parasitic Infections Issue Among Orang Asli In Pahang Towards Developing Health Literacy Module.
Ph.D
Completed
2023
Main Supervisor
|
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Development Of An Aviation-Based Teamwork And Communication Training Programme Among Healthcare Professionals In Pahang Government Hospitals.
Ph.D
Completed
2023
Co-supervisor
|
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Analysing Smoking Cessation Strategies Towards Developing Potential Anti-Smoking Promotion For Adult Smokers In Kuantan.
Ph.D
Completed
2022
Main Supervisor
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Study On Knowledge, Attitude, And Practice With Investigation On Household Insecticide Aerosol Spray Toxicity In Kuantan Towards Development Of Education Material.
Ph.D
Completed
2021
Main Supervisor
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Effects Of Flaxseed Extract On Osteoblast Differentiation Potential Of Stem Cells From Human Exfoliated Deciduous Teeth
.
Ph.D
Completed
2021
Co-supervisor
|
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Physicochemical Analysis And Shelf-Life Study Of Soft Jelly Prepared From Baccaurea Angulata Fruit Juice Enriched With Trigona Bee Honey And Its Effects On Orl115 And Orl188 Cancer Cell Lines.
Ph.D
Completed
2021
Co-supervisor
|
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Depression And Hiv: Exploring Experience Of Women And Health Care Providers In Ethiopia.
Ph.D
Completed
2020
Member Supervisory Committee
|
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Prevention Of Fragility Fracture Among Post Menopausal Women: Needs Assessment And The Development Of Bone Health Educational Booklet.
Ph.D
Completed
2019
Main Supervisor
|
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The Toxicity Study Of Aquilaria Malaccensis (Agarwood) Leaves Aqueous Extract On Male Reproductive System In Sprague Dawley Rats.
Ph.D
Completed
2019
Main Supervisor
|
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Effect Of Nurse-Led Motivational Construct Intervention Programme On Lifestyle Changes And Cardiometabolic Risk Among Obese Adults: A Single-Blind Randomised Controlled Trial.
Ph.D
Completed
2018
Member Supervisory Committee
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Cytotoxic Effects And Mechanisms Of Cell Death Of Artocarpus Altilis On Human Breast, Colon, Lung And Skin Cancer Cells.
Ph.D
Completed
2018
Co-supervisor
|
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Development Of Islamic Ethical Framework On Harm Prevention In Nursing Practices.
Ph.D
Completed
2018
Co-supervisor
|
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Fundamental Study Of Spermatogenesis In Vitro From Two Types Of Azoospermic Testicular Biopsy.
Ph.D
Completed
2017
Main Supervisor
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Exploration Of Somatic Cell Nuclear Transfer Protocol Using Rodent As A Model Towards The Conversation Of Endangered Species.
Ph.D
In Progress
Main Supervisor
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Impact Of Oxytocin On Sensory And Behavior Issues In Rats.
Ph.D
In Progress
Main Supervisor
|
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The Role Of Trihoney™ Supplementation On The Oxidative Stress And Proteomic Profile Of Seminal Samples From Infertile Obese Men.
Ph.D
In Progress
Co-supervisor
|
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Generation Of Crispr Knockout Models Of Heterozygous Hepatocyte Nuclear Factor-Ib (Hnf1b) Towards Understanding Kidney Diseases.
Master
Completed
2025
Co-supervisor
|
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In-Vitro Maturation Of Oocytes Using Balb/C Mice As Mammalian Model For Convervation Of Endangered Species Animal.
Master
Completed
2024
Co-supervisor
|
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Optimizing In Vitro Maturation Protocols For Conservation Breeding Of Proboscis Monkeys (Nasalis Larvatus) Using Wild Macaques (Macaca Fascicularis) As A Model.
Master
Completed
2024
Co-supervisor
|
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Myo-Inositol And Its Ameliorative Effects On
Cryo-Survival Of Post-Thaw Abnormal Human
Sperm Quality.
Master
Completed
2023
Co-supervisor
|
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Establishing A Standdard Fibroblast Cell Line Derived From Kidney Tissue Of Sumatran Rhinoceros (Puntung).
Master
Completed
2020
Main Supervisor
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Identification The Level Of Knowledge, Attitude And Practice Towards Hazardous Chemicals And Its Health Effects Among Offshore Workers In Oil And Gas Industries.
Master
Completed
2020
Main Supervisor
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Knowledge, Attitude And Practice Among Petroleum Industry Employees And Employers' Preparedness Towards Occupational Safety And Health.
Master
Completed
2020
Main Supervisor
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In Vitro Investigation And Assessment Of Knowledge, Attitude And Practice Among Community Towards The Effect Of Monosaccharides On Cancer
.
Master
Completed
2020
Main Supervisor
|
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Evaluation Of Mir-21 And Mir-145 Expression In Cryptosporidium Parvum Infected Hct-8 And Ht-29 Cell Lines.
Master
Completed
2019
Co-supervisor
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The Assessment Of Water Quality In Two Main Rivers In Kuantan, Pahang.
Master
Completed
2018
Co-supervisor
|
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Evaluation Of Amel And Testis-Specific Protein Y-Encoded (Tspy) Gene Markers For Accurate Sex Determination Using Sybr Green Real-Time Pcr On Malaysian Kedah-Kelantan Cattle.
Master
In Progress
Main Supervisor
|
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A Comparative Study On Response Of Penissetum Purpureum'S Morphological Growth And Forage Quality On Infertile Soil.
Master
In Progress
Co-supervisor
|
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The Effects Of Mindfulness As The Psychological Intervention On Perceived Stress And Cortisol Level Among Breastfeeding Mothers With Intrauterine Growth Restriction (Iugr) Babies.
Master
In Progress
Co-supervisor
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Establishment Of Voluntary Module In Planetary Health For Youth Empowerment Among School Students.
Master
In Progress
Co-supervisor
|
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Development Of An Isothermal Dnazyme Assay For The Rapid And Sensitive Detection Of Candida Genus Level And Drug-Resistant Candida Species.
Master
In Progress
Co-supervisor
|
Research Projects
Completed
| 2024 - 2024 | Assessment of the Level of Depression, Anxiety, Stress and Coping Strategies of Caregivers in Caring for their Special Needs Children in Kuantan |
| 2023 - 2024 | SOUL OF ANAK PUSU |
| 2023 - 2024 | FISH FOR SUSTAINABLE WELLBEING OF PERLIS ASNAF COMMUNITY |
| 2021 - 2023 | Kelulut Propolis Extraction Made Easy ? Training of Trigona Propolis extraction using easy and economical method for local apiculture small and medium enterprises (SMEs) |
| 2021 - 2022 | Knowledge Transfer on Sexual Transmitted disease and Breast Implant complications Among LGBT |
| 2020 - 2021 | Establishment of Desa Kelulut as a Sustainable Stingless Bee Farming Project for Economic Empowerment among B40 Community at Kampung Bukit Kuin, Kuantan, Pahang in Post-COVID-19 Time |
| 2020 - 2024 | Knowledge, attitude and practice on upon discovering dead endangered species among rural community and optimisation of sample collection procedures for reviving functional cell of endangered species |
| 2019 - 2022 | Bioactive compounds of A.malaccensis leaf and their mechanistic roles in inflammation and immunomodulation in zebrafish model |
| 2019 - 2019 | Cytocompatibility Test for Material |
| 2019 - 2021 | Integrated Sexual and Reproductive Health for Adolescents (ISRHeA) Module as a Strategy to Prevent Poor Sexual Health |
| 2019 - 2023 | Transferring Smoking Knowledge & Skills to 'Pembimbing Rakan Sebaya' (PRS), of Jabatan Bomba & Penyelamat Malaysia (JBPM) Negeri Pahang: Towards Reduction of Smokers among Fire Bridget in Pahang |
| 2019 - 2023 | Development of Silage Based on Napier Grass Enriched with Rice Straw and Leucaena Leucocephala to Increase Meat Production in Beef Cattle |
| 2018 - 2018 | Probiotic Treatment on Rat Project |
| 2018 - 2020 | In vitro effect of Tamarindus indica as a potential anti-larvae of screwworm maggots obtained from goats with myiasis |
| 2018 - 2018 | Consultantation Service on Cell Culture Analysis |
| 2018 - 2024 | Genomic determinants of specific virulence gene(s) of Cryptosporidium and its role in the pathogenesis of cryptosporidiosis and low milk production in goats |
| 2018 - 2019 | Knowledge Transfer to Small Holder Goat Farmers on Rotational Grazing to Reduce Parasitic Infections |
| 2017 - 2018 | Application of Advanced Reproductive Technology in Conservation Wildlife in Sabah |
| 2017 - 2017 | Transfer of Knowledge to Goat Farmers on Improving and Formulating Proper Feeding using Local Crops: Towards Sustainable Health, Milk and Meat Production |
| 2017 - 2020 | Sperm DNA fragmentation among smokers and non-smokers as measured by sperm chromatin dispersion test |
| 2017 - 2017 | Consultation Service On Cell Culture Analysis |
| 2017 - 2019 | EFFECTS OF SPERM FROM Aquilaria malaccencis TREATED SPRAGUE DAWLEY RATS TOWARDS EARLY EMBRYO DEVELOPMENT IN VITRO |
| 2016 - 2018 | Fertility Enhancing Effect of Aquilaria malaccensis Leave Extrct in Sprague Dawley Rats Prior Exposure to Cyclophosphamide |
| 2016 - 2018 | Phytochemical Analysis and Toxicity Study of Aquilaria malaccensis Leaves Extract in Sprague Dawley Rats |
| 2016 - 2018 | Protective Effects of Aquilaria malaccensis Leaves Extract against Sperm DNA Damage on Sprague Dawley Rats due to Cyclophosphamide Exposure |
| 2016 - 2017 | The development of in vitro human fibroblast feeder line |
| 2016 - 2020 | Determining Factors Associated with High-sensitivity C-reactive protein level in Obese Women |
| 2016 - 2020 | Development and Formulation of a fixed dose combination of carbamazepine and gabapentin a Novel Approach to Increase Therapeutic efficacy for Peripheral Neuropathic Pain in Diabetic Patient |
| 2015 - 2019 | Development Of Home ? Based Lifestyle Modification Program In Preventing Fracture Among Post-Menopausal Osteoporotic Women |
| 2015 - 2019 | Investigation of Glycoconjugated Gold Nanoparticles in the Inhibition of the Pathogen and Cancer Cells |
| 2015 - 2023 | Upscale Production of the High Antioxidant Jelly Prepared from Baccaurea Angulata Fruit Enrich with Trigona Bee Honey for Head and Neck Patients |
| 2015 - 2018 | Islamic Ethical Principle of Harm Prevention (Daf'U al-Darar) and its Applications in Nursing Practices |
| 2014 - 2018 | Identification of Specific Mirna Expression of Cryptosporidium in HCT-8 Cell and its Pathway as Fundamental Role in Pathogenesis Mechanisms |
| 2013 - 2017 | Isolation, Quantification and Formulation of Bioactive Peptides (Adipokines) for Diabetes and Obesity From Adipose Tissues In Halal Meat |
| 2013 - 2017 | Salvaging the Embryo From Effects of Toxic Paternal Exposure |
| 2012 - 2015 | Potential development of mature spermatozoa using IVF medium with additional of hormones and antioxidant supplement |
| 2011 - 2014 | Biochemical Characterization for Matrix Metalloproteinases (Collagenases) Regulation via Novel CTCF/YB-1 Protein Interaction for Potential Targeted Therapy of Human Cancers |
| 2011 - 2013 | RU 2011 -Comparison between IVF Medium and stem cell medium for potetial development of mature sperm cells using rFSH, testosterone and zinc supplement. |
| 2011 - 2013 | RU 2011 - Derivation of primary mouse embryonic fibroblast (PMEF) as feeders for embryonic stem cells culture. |
On-Going
| 2025 - Present | The impact of mindfulness as a psychological intervention among mothers of babies with intrauterine growth restriction (IUGR) in promoting breastfeeding |
| 2024 - Present | Elucidating the Role of Lambda Exonuclease in Multi-component Deoxyribozyme (DNAzyme) for the Generation of Single-stranded DNA. |
| 2024 - Present | A comparison study on the nutritional quality of Penissetum purpureum (Napier grass) silage stored at three different durations for determination of optimum storage duration of P. purpureum silage |
| 2023 - Present | Enhancing the Functions of Frozen Zoo in Contributing to the National Plan for Conservation Activities of the Endangered Species |
| 2022 - Present | Expanding Project of the First South East Asian Frozen Zoo at IIUM for Endangered Species in Malaysia |
| 2022 - Present | Strengthening the Functions of the Established Frozen At IIUM in Contributing to the Conservation Plans for Endangered Species in Malaysia |
| 2022 - Present | 2nd Nusantara Ibadah Camp for LGBT Community |
| 2021 - Present | Modelling genetic kidney malformations using CRISPR/Cas9-edited 3D organoids derived from pluripotent stem cells to understand pathomechanism of human kidney disorders |
| 2021 - Present | Understanding the Role of Trihoney? Supplementation on the Oxidative Stress and Proteomic Profile of Seminal Samples from Infertile Obese Men |
| 2021 - Present | INTEGRATION OF MAQASID AL-SHARI?AH AS A RECIPROCAL FRAMEWORK IN STEM CELL-DERIVED ORGAN SYNTHESIS |
| 2021 - Present | A Model for Skyline Queries Over Knowledge Large-Scale Uncertain and Incomplete Graphs |
| 2021 - Present | Prenatal Developmental Toxicity Study of Aquilaria malaccensis Leaves Aqueous Extract in Pregnant Sprague Dawley Rats. |
| 2021 - Present | In Vitro Evaluation of Safety Profiles, Cellular Responses and Genotoxicity of Nanostructured Tin (IV) Oxide, SNO2 on Human-Derived Pluripotent Stem Cell Lines |
| 2020 - Present | Elucidation of Physical, Behavioural, and Biological Changes on the Captive Malayan Gaurs Undergoing Natural Taming Process Towards Enhancing Domestication. |
| 2020 - Present | Establishment of Frozen Zoo for Endangered Species in Malaysia |
| 2020 - Present | Establishment of Alkaline Phosphatase Monoclonal Antibody towards Fibroblast Cell Line of Sumatran Rhinoceros (Dicerorhinus sumatrensis) |
| 2019 - Present | INTERNATIONAL COURSE ON LABORATORY ANIMAL SCIENCE |
| 2016 - Present | Development of an Aviation-based Teamwork and Communication Training Programme to Improve Patient Safety in Malaysian Hospitals |
| 2013 - Present | IIUM MOLECULAR AND CELLULAR BIOLOGY RESEARCH CLUSTER (iMoleC) |
| 2013 - Present | Development and Toxicity of Halal Herbal Supplement Prepared from Acalypha Indica for Male Fertility with Novel Molecular Approach |
| 2012 - Present | Orthopaedics, Musculoskeletal and Bioethical Research Unit |
| 2006 - Present | Laparoscopic Hernioplasty Under Spinal Anesthesia |
| - | Knowledge and Investigation of Toxicity in Commonly Use Household Insecticide in Kuantan |
| - | Knowledge and Investigation of Toxicity in Commonly Use Household Insecticide in Kuantan |
| - | Optimization of in-vitro maturation (IVM) protocols using Macaque fascicularis as a model towards conservation of Proboscis monkey (Nasalis larvatus) as endangered species |
| - | Optimization of in-vitro maturation (IVM) protocols using Macaque fascicularis as a model towards conservation of Proboscis monkey (Nasalis larvatus) as endangered species |
Awards & Recognition
| 17 Dec, 2021 | Highest Citation in Citation Index Journal Award - KULLIYYAH OF NURSING | University |
| 17 Dec, 2021 | KON TAKRIM DAY 2021: JOURNAL ARTICLE PUBLICATION AWARD - KULLIYYAH OF NURSING | University |
| 17 Dec, 2021 | KON TAKRIM DAY 2021: TOP FIVE (5) CONTRIBUTORS TO KON'S RESEARCH PERFORMANCE - KULLIYYAH OF NURSING | University |
| 17 Dec, 2021 | KON TAKRIM DAY 2021: BEST RESEARCHER AWARD - KULLIYYAH OF NURSING | University |
| 17 Dec, 2021 | KON TAKRIM DAY 2021: HIGH IMPACT RESPONSIBLE RESEARCH AWARD - KULLIYYAH OF NURSING | University |
| 10 Dec, 2021 | TOP RESEARCHERS WITH THE HIGHEST AMOUNT OF GRANTS RECEIVED FROM 2019-2021 - International Islamic University Malaysia | University |
| 10 Dec, 2021 | TOP RESEARCHERS WITH THE HIGHEST NUMBER OF JOINT PUBLICATIONS FROM 2019-2021 - International Islamic University Malaysia | University |
| 26 Sep, 2021 | Gold Medal - Climate Governance Malaysia | International |
| 30 Mar, 2021 | Best Paper Award - Others | National |
Publications
Articles
Conference or Workshop Items
Books
| 2024 | Awareness of in fertility among men and women in Kuantan, Pahang. IIUM PRESS, ISBN: |
| 2022 | MANUAL FOR IBADAH CAMP ORGANIZER A PART OF THE IIUM FLAGSHIP ENTITLED “GENDER DYSPHORIA”. IIUM Press, ISBN: 978-629-97442 |
| 2022 | MANUAL FOR IBADAH CAMP ORGANIZER A PART OF THE IIUM FLAGSHIP ENTITLED “GENDER DYSPHORIA”. IIUM Press, ISBN: 978-629-97442 |
| 2022 | MANUAL FOR IBADAH CAMP ORGANIZER A PART OF THE IIUM FLAGSHIP ENTITLED “GENDER DYSPHORIA”. IIUM Press, ISBN: 978-629-97442 |
| 2022 | MANUAL FOR IBADAH CAMP ORGANIZER A PART OF THE IIUM FLAGSHIP ENTITLED “GENDER DYSPHORIA”. IIUM Press, ISBN: 978-629-97442 |
| 2022 | Penternakan kambing secara komersial. Dewan Bahasa dan Pustaka, Malaysia, ISBN: 978-983-49-3415-6 |
Book Sections
| 2014 | Stem cells research: value, ethical and religious views. In: IIUM Press, ISBN: 978-967-418-269-4, pp. 186-195 |