Staff Directory


Azlini Binti Ismail

Academic Qualifications

  • Doctor of Philosophy in Pharmacology - Doctor of Philosophy, Universiti Sains Malaysia (USM)
  • Bachelor of Biotechnology (Honours) - Bachelor Degree, International Islamic University Malaysia

Azlini Binti Ismail (Assoc. Prof. Ts. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF DENTISTRY


dr_azlini@iium.edu.my
2957


Expert Profile


Assoc. Prof. Ts. Dr. Azlini Ismail is a highly motivated academician and a passionate researcher in the field of pharmacology. A recipient of the Best Student (Academic) Award during the 25th IIUM Convocation, she graduated with First Class Honors in Biotechnology from the International Islamic University Malaysia (IIUM) and went on to complete her fast-track Ph.D. in Pharmacology in 2015 at University Sains Malaysia. Since then, she has dedicated her career to advancing knowledge in pharmacology and pharmacognosy, specifically focusing on natural products, antihypertensive research, and phytochemical profiling using GCMS and LCMS. Currently serving as the Deputy Dean of Postgraduate and Responsible Research at the Kulliyyah of Dentistry, IIUM, she plays a key role in fostering a research-driven environment. Dr. Azlini is also the Deputy Editor-in-Chief of the IIUM Journal of Orofacial and Health Sciences and an pnael of the IIUM Animal Care and Use Committee, underscoring her commitment to responsible research practices. Her leadership extends beyond academia, as she was recently elected Vice President of the Malaysian Society of Pharmacology and Physiology (MSPP) for 2024-2026. Over the years, she has spearheaded impactful research projects, including the IIUM Research Initiative Grant Scheme (2015-2019), MOHE's Fundamental Research Grant Scheme (2019-2021), and is currently leading an exciting study on the therapeutic potential of kelulut honey under FRGS 2022. Her work bridges academia and industry, having completed multiple industry-sponsored projects, and she actively supervises both undergraduate and postgraduate students in Masters and Ph.D. programs. Her expertise in pharmacology, natural product research, and her extensive research experience with in vitro and in vivo animal studies and her ability to bridge academia and industry makes her an ideal partner for multidisciplinary projects in pharmacology and natural product research.


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Pharmacology ~ Medical Pharmacology
  • Medical And Health ~ Medical And Health Sciences ~ Complementary/Alternative Medicine ~ Traditional Medicine and Natural Product (Including Development of Traditional and Herbal Medicine)


Professional Membership


  • 2018 - 2018 : Member of Profesional Body / Association: (Early Career Member), British Pharmacological Society
  • 2018 - 2021 : Member of Profesional Body / Association: (Member), Laboratory Animal Science Association of Malaysia
  • 2019 - 2022 : Member of Profesional Body / Association: (Member), Malaysian Natural Products Society
  • 2020 - 2022 : Member of Profesional Body / Association: (Honorary Secretary), Malaysian Society of Pharmacology and Physiology
  • 2022 - 2024 : Member of Profesional Body / Association: (Full Member), British Pharmacological Society
  • 2022 - 2024 : Member of Profesional Body / Association: (Executive Committee), Malaysian Society of Pharmacology and Physiology
  • 2022 : Member of Profesional Body / Association: (Graduate Technologist), Lembaga Teknologis Malaysia
  • 2022 - 2024 : Member of Profesional Body / Association: (Professional Technologist), Malaysian Board of Technologists
  • 2024 - 2026 : Member of Profesional Body / Association: (Vice President), Malaysian Society of Pharmacology and Physiology


Teaching Responsibilities


CARDIOVASCULAR & RESPIRATORY SYSTEMS 2024/2025
DISSERTATION 2022/2023
ENDOCRINE, GENITOURINARY, LOCOMOTOR SYSTEMS 2024/2025
GASTROINTESTINAL, HEPATOBILIARY AND HEMATOPOIETIC SYSTEMS 2024/2025
HEAD & NECK AND NERVOUS SYSTEMS 2024/2025
NORMAL RESPONSE TO DISEASED STATE & BASIC PHARMACOLOGY 2024/2025 2023/2024
PHARMACOLOGY 2023/2024
PHYSIOLOGY 2022/2023
RESEARCH METHODOLOGY 2024/2025 2022/2023
UNIFIED ISLAMIC INPUT 2022/2023


Supervision


Elucidating The Prophylactic Potential Of Kelulut Honey (Kh) In Modulating Angiotensin-Converting Enzyme 2 (Ace-2) As Covid-19 Target Enzyme.
Ph.D In Progress Main Supervisor
In Vitro Study Of Anti-Inflammatory Activity Of Syzygium Polyanthum And Its Antimicrobial And Antibiofilm Againts Candida Spp. On Diffrent Type Of Denture Bases.
Ph.D In Progress Co-supervisor
The Effect Of Fluoride-Enriched Flaxseed Oil Toothpaste On Enamel Morphology, Antimicrobial Efficacy, And Remineralization Potential. In Vitro Study .
Ph.D In Progress Co-supervisor
Mechanism And Specificity Of Angiotensin Converting Enzyme Inhibition Activity By Syzygium Polyanthum Wight (Walp.) Leaves.
Master Completed 2021 Main Supervisor
Bio-Assay Guided Fractionation And Identification Of Antihypertensive Compounds From Syzygium Polyanthum (Wight) Walp. (Serai Kayu) Leaves.
Master Completed 2019 Main Supervisor


Research Projects


Completed
2022 - 2023 I DO CARE 2.0
2021 - 2022 Evaluation of Antioxidant Activity of GOLDEN SPRAY ANTI-V
2021 - 2022 Elucidation of Contents in GOLDEN SPRAY ANTI-V
2021 - 2024 Evaluation of Anti-inflammatory property of Golden Spray Anti-V
2018 - 2022 Evaluation of antihypertensive mechanisms and pathways modulated by Syzygium polyanthum leaves fraction: In vitro study.
2017 - 2021 Epithelization, ossification and gene expression of the socket after tooth extraction in diabetic rats treated by flax seed extract
2015 - 2018 Bio-Assay Guided Fractionation of Hypotensive Compounds from Syzygium Polyanthum Wight (Walp.)var. Polyanthum Leaves
On-Going
2025 - Present The Effect of Flax Seed Oil Extract on Morphological Characteristics of Enamel (In Vitro Study)
2024 - Present In Vitro Study of Anti-Inflammatory Activity of Syzygium polyanthum, Its Antimicrobial and Antibiofilm Activities Against Candida Species on Different Type off Denture Bases
2022 - Present Elucidating the prophylactic potential of Kelulut honey in modulating angiotensin-converting enzyme 2 (ACE2) as COVID-19 target enzyme
2020 - Present The microbial growth inhibition using lemongrass extract as an endodontic irrigant.


Awards & Recognition


15 Sep, 2022 Gold Medal Award - Applied Health Sciences Category - IIUM Research & Innovation Day 2022 - International Islamic University Malaysia University
28 Mar, 2022 Silver Medal Award (Oral Category)- 11th Dental Students' Scientific Conference 2022 - Kulliyyah of Dentistry, IIUM KCDIO
28 Mar, 2022 Gold Medal Award (Oral Category)- 11th Dental Students' Scientific Conference 2022 - Kulliyyah of Dentistry, IIUM KCDIO
28 Mar, 2022 Gold Medal Award (Poster Category)- 11th Dental Students' Scientific Conference 2022 - Kulliyyah of Dentistry, IIUM KCDIO
28 Mar, 2022 Gold Medal Award (Poster Category)- 11th Dental Students' Scientific Conference 2022 - Kulliyyah of Dentistry, IIUM KCDIO
24 Nov, 2021 Gold Medal Award Applied Sciences Category - IIUM Research Day 2021: An International Online Event for Life Sciences - Research Management Centre, International Islamic University Malaysia International
24 Nov, 2021 Gold Medal Award Basic Sciences Category - IIUM Research Day 2021: An International Online Event for Life Sciences - Research Management Centre, International Islamic University Malaysia International
09 Nov, 2012 BPS Bain Memorial Bursary Fund Award - British Pharmacological Society International


Publications


Articles

2025 An ensemble docking-based virtual screening and molecular dynamics simulation of phytochemical compounds from Malaysian Kelulut Honey (KH) against SARS-CoV-2 target enzyme, human angiotensin-converting enzyme 2 (ACE-2). Journal of Biomolecular Structure and Dynamics, 43 (11) pp. 5393-5422
2025 Impact of WhatsApp on improving denture care knowledge and the awareness of the relationship between edentulism and general health. The Journal of Prosthetic Dentistry, 133 (6) pp. 1560-1568
2025 Medicinal plants in the Southeast Asia for treatment and prevention of oral cancer: a systematic review. Journal of Pharmacy & Pharmacognosy Research, 13 (4) pp. 1003-1037
2024 Artificial intelligence to predict pre-clinical dental student academic performance based on pre-university results: a preliminary study. Journal of Dental Education, Volume 88, Issue 12 (12) pp. 1-15
2024 Orthodontic patient’s perspectives, attitudes, and readiness toward teleorthodontics. Journal of International Oral Health, 16 (1) pp. 82-89
2024 Therapeutic effect of natural herbs in dentistry: a narrative review. Journal of Health and Translational Medicine, 1 () pp. 187-203
2023 Amlodipine and Xerostomia in elderly patients. Journal of International Dental and Medical Research, 16 (2) pp. 709-713
2023 Beyond sweetness: the nutritional and medicinal treasure of honey. Microcredential @ IIUM, 26 Dec 2023 () pp.
2023 LC-MS/MS-QTOF dataset of compounds detected in kelulut honey of the stingless bees, Heterotrigona itama and Tetrigona binghami from Kuantan, Pahang, Malaysia. Data in Brief, 49 (August 2023) pp. 1-8
2023 Self-medication practice for dental problems: a cross-sectional study among adults in Kuantan, Pahang in Peninsular Malaysia. Journal of International Oral Health, 15 (2) pp. 184-193
2023 Solanum torvum for hypertension: a systematic review. Research Journal of Pharmacognosy, 10 (2) pp. 75-84
2022 Angiotensin Converting Enzyme (ACE) inhibitionactivity by Syzygium polyanthum Wight (Walp.) leaves: mechanism and specificity. Pharmacognosy Journal, 14 (1) pp. 763-84
2022 Impact of COVID‑19 on Malaysian dental students’ physical, mental, financial and academic concerns. BMC Oral Health, 22 () pp. 1-9
2022 Online learning during the Covid-19 pandemic: dental students’ perspective and impact on academic performance, one institution experience. Dentistry Journal, 10 (7) pp. 1-12
2022 Remote teaching and learning during COVID-19 “lockdown” period in Malaysia: one institution’s experience. IIUM Journal of Orofacial and Health Sciences, 3 (1) pp. 156-158
2022 The past and the present use of traditional herbal medicine. Microcredential @ IIUM, () pp.
2022 Traditional herbal medicine: is it always safer than conventional medicine?. Microcredential @ IIUM, 31 December 2022 () pp.
2021 COVID-19 buka prospek penyelidikan baharu. Berita Harian Online, 17 August 2021 () pp.
2021 Knowledge, perceived risk, and preventive behaviors amidst Covid-19 Pandemic among dental students in Malaysia. Dentistry Journal, 9 (12) pp. 1-12
2021 Kuasai teknologi AI percepat usaha tangani COVID-19. Berita Harian, 20 September 2021 () pp. 12-12
2021 LCMS dataset on compounds in syzygium polyanthum (wight) walp. leaves variant from the East coast of Peninsular Malaysia. Data in Brief, 39 () pp.
2021 Time-series forecasting analysis on the major treatment need among patients referred for periodontal and conservative treatments in IIUM dental outpatient clinic. Journal of International Oral Health, 13 (5) pp. 485-492
2020 Antihypertensive assay-guided fractionation of Syzygium polyanthum leaves and phenolics profile analysis using LCQTOF/MS. Pharmacognosy Journal, 12 (6(S)) pp. 1670-1692
2020 Dental treatment needs among patients undergoing screening at a university-based dental institution in Kuantan, Pahang, Malaysia. International Journal of Orofacial and Health Sciences, 1 (1) pp. 18-27
2020 Southeast Asian medicinal plants with angiotensin converting enzyme (Ace) inhibition properties. Pharmacognosy Journal, 12 (6) pp. 1429-1439
2020 The impact of COVID-19 pandemic on research. IIUM Journal of Orofacial and Health Sciences, 1 (2) pp. 56-58
2019 Morphological evaluation of aortic vessel in Spontaneously Hypertensive Rat (SHR) Models. Annals of Microscopy, 18 () pp. 4-10
2019 Syzygium polyanthum (Wight) walp: a potential phytomedicine. Pharmacognosy Journal, 11 (2) pp. 429-438
2018 Acute and sub-acute antihypertensive effects of syzygium polyanthum leaf extracts with determination of gallic a using HPLC analysis. Pharmacognosy Journal, 10 (4 (July-August)) pp. 663-671
2018 Amelioration of aorta morphology in spontaneous hypertensive rat (SHR) by syzygium polyanthum. International Journal of Cardiology, 273 (Supplement) pp. 20
2018 Antihypertensive effect of fractions derived from an aqueous extract of Syzygium polyanthum on anaesthetized spontaneously hypertensive rats. Health and the Environment Journal, 9 (Supplement 1) pp. 14
2018 GC-MS analysis of phytochemical compounds in syzygium polyanthum leaves extracted using ultrasound-assisted method. Pharmacognosy Journal, 10 (1) pp. 110-119
2017 Autonomic receptors and nitric‑oxide involvements in mediating vasorelaxation effect induced by syzygium polyanthum leaves extract. Pharmacognosy Research, 9 (Supp 1) pp. S9-S14
2013 Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats. Evidence-Based Complementary and Alternative Medicine, 2013 () pp. 1-16
2011 Hypotensive effects of aqueous extract of Eugenia polyantha leaves are partly mediated via cholinergic receptor. Conference Proceedings 16th National Conference on Medical and Heath Sciences, () pp. 20-28
Conference or Workshop Items

2022 Artificial Intelligence (AI) to predict dental student academic performance based on pre-university results. In: National Oral Health Research Initiative (NOHRI) Conference 2022,
2022 IIUM dental students' perspective on implementation of online learning and the impact on academic performances during COVID 19 pandemic. In: 11th Dental Students' Scientific Conference,
2022 Impact of Covid-19 among dental students in Malaysia. In: Malaysia International dental Show,
2022 Impact of COVID-19 among dental students in Malaysia. In: 11th Dental Students' Scientific Conference,
2022 Knowledge, perceived risk and the associated preventive behaviours amidst COVID-19 pandemic among undergraduate dental students in Malaysia. In: 11th Dental Students' Scientific Conference,
2022 Knowledge, perceived risk, and preventive behaviours amidst Covid-19 Pandemic among dental students in Malaysia. In: Malaysia International Dental Show,
2022 Online learning during the Covid 19 Pandemic: dental students’ perspective and impact on academic performance, one institution experience. In: Malaysia International Dental Show,
2022 Orthodontic patient's perspective, attitude and readiness towards tele-orthodontics. In: 11th Dental Students' Scientific Conference,
2022 Total flavonoid content, total phenolic content, and the antioxidant activity of Hurrem Titisemas Liquid. In: IIUM Research and Innovation Day 2022,
2021 Angiotensin-converting enzyme inhibition activity and LCMS analysis of Syzygium polyanthum (Wight) Walp leaves. In: National Symposium on Essential Oils, Plants, Cosmetic and Health,
2021 Artificial Intelligence (AI) to predict dental student academic performance based on pre university results. In: Practical Machine Learning and Artificial Intelligence from PRAGMA Community,
2021 Knowledge, perceived risk, and preventive behaviours amidst Covid-19 pandemic among dental students in Malaysia. In: The 32nd Annual Scientific Meeting of The South East Asia Association for Dental Education,
2021 Mechanism of angiotensin converting enzyme (ACE) inhibition by Syzygium polyanthum wight (WALP.) leaves. In: IIUM Research Day 2021: An International Online Event for Life Sciences,
2021 Molecular binding interaction of angiotensin converting enzyme and 1-galloyl glucose, the major compound in Syzygium polyanthum leaves. In: 7th International Conference on Advancement in Science and Technology (iCAST2021),
2021 Pattern of medication use among the elderly at one nursing center for terminally-ill patients in the east coast Malaysia: a cross-sectional study. In: IIUM Research Day 2021: An International Online for Life Sciences,
2020 Prevalence, pattern and attitude towards self-medication practice for dental problems in Kuantan, Pahang. In: 9th Dental Students' Scientific Conference,
2020 Solanum torvum for hypertension in ‘Kitab al-tibb’: A systematic review on the scientific evidence. In: International Conference on Malay Medical Manuscript (ICOMMM) 2020,
2019 Correlation analysis between antihypertensive effect with total phenolic content and antioxidant activity of syzygium polyanthum (Serai Kayu) leaves fractions. In: Kuantan Research Day 2019,
2018 Amelioration of aorta morphology in a spontaneous hypertensive rat (shr) by Syzygium polyanthum. In: NHAM-CRM Research Track 2018,
2018 Antihypertensive effect of fractions derived from aqueous extract of syzygium polyanthum on anaesthetized spontaneously hypertensive rats. In: Health Sciences Symposium (HSS) 2018,
2018 Time-series forecasting analysis on dental treatment need of first-visit patients at IIUM Dental Outpatient Clinic (Periodontal and Conservative Department) for the year 2017 and 2018. In: 7th Dental Students' Scientific Conference,
2017 Dental treatment need among first-visit patients of Dental Outpatient Clinic at IIUM Kuantan for the year 2016. In: 1st IIUM International Dental Conference 2017 in Commemoration of the Kulliyyah of Dentistry 10th Anniversary (1st IIDC),
2017 Effects of different types of Syzygium Polyanthum leaves extracts on blood pressure of anaesthetized Spontaneously Hypertensive rats. In: NHAM-CRM Research Track,
2016 Vasorelaxation effect of Syzygium polyanthum (wight) walp. Leaves extract on isolated thoracic aorta rings of normal and hypertensive rats. In: Medical Research Symposium & Pacific Partnership in conjunction with Kuantan Research Day 2016,
2012 Hemodynamic effects of the aqueous extracts of syzygium polyanthum Wight. Walp. Var. Polyanthum leaves on normotensive and hypertensive rats: comparisons of dose response curves and time-course effects. In: British Pharmacological Society Winter Meeting 2012,
Books

2022 Compendium of dental sciences research. Kulliyyah of Dentistry, International Islamic University Malaysia, ISBN:
2021 Kulliyyah of Dentistry online examination: student’s guide. Kulliyyah of Dentistry, International Islamic University Malaysia, ISBN:
2021 Kulliyyah of Dentistry online examination: student’s guide. Kulliyyah of Dentistry, International Islamic University Malaysia, ISBN:
Book Sections

2024 Effectiveness of gargling with 100% coconut oil to prevent plaque accumulation and gingival bleeding. In: CRC Press, Taylor & Francis Group, ISBN: 978-1-032-51441-3, pp. 429-434
2022 A pilot study on expectation and satisfaction of denture patients in IIUM dental clinic. In: Kulliyyah of Dentistry IIUM, ISBN: , pp. 47-72
2022 A pilot study on expectation and satisfaction of denture patients in IIUM dental clinic. In: Kulliyyah of Dentistry IIUM, ISBN: , pp. 47-72
2022 Quality of life (QOL) of patient wearing removable denture after taking treatment in polyclinic, Kulliyyah of Dentistry, IIUM. In: Kulliyyah of Dentistry, International Islamic University Malaysia, ISBN: , pp. 73-94
2022 Quality of life (QOL) of patient wearing removable denture after taking treatment in polyclinic, Kulliyyah of Dentistry, IIUM. In: Kulliyyah of Dentistry, International Islamic University Malaysia, ISBN: , pp. 73-94
2021 In vitro angiotensin-converting enzyme (ACE) inhibition activity of Syzygium polyanthum leaves and its inhibition mechanism. In: Frontiers, ISBN: 978-2-88971-008-9, pp.
2021 In vitro angiotensin-converting enzyme (ACE) inhibition activity of Syzygium polyanthum leaves and its inhibition mechanism. In: Frontiers, ISBN: 978-2-88971-008-9, pp.
Monograph

2020 Chemical compounds identified in Syzygium polyanthum leaves and its respective concentration and retention time at LC-QTOF-MS. In: ,
2018 Bio-assay guided fractionation of hypotensive compounds from syzygium polyanthum wight (WALP.)Var. Polyanthum leaves. In: ,