Staff Directory


Irna Elina Binti Ridzwan

Academic Qualifications

  • Ph.D in Pharmacy and Pharmacology - Doctor of Philosophy, University of Bath
  • Bachelor of Pharmacy (Honours) - Bachelor Degree, Universiti Sains Malaysia (USM)

Irna Elina Binti Ridzwan (Dr.)

Assistant Professor
IIUM Kuantan Campus

KULLIYYAH OF PHARMACY

elina@iium.edu.my
3052


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Medical Diagnostic Imaging ~ Other Medical Diagnostic Imaging n.e.c. - Semi-synthesis (opioids)
  • Medical And Health ~ Medical And Health Sciences ~ Other Medical and Health Sciences n.e.c. - Drug addiction (opioids)
  • Medical And Health ~ Medical And Health Sciences ~ Clinical Medicine ~ Anaesthesiology - Opioids pharmacology


Professional Membership


  • 2013 : Member of Profesional Body / Association, Malaysia Pharmaceutical Society (MPS)


Teaching Responsibilities


ANTI CANCER CHEMOTHERAPY 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013
ANTI-INFECTIVE AGENTS 2024/2025 2023/2024 2022/2023 2021/2022 2020/2021
ANTI-INFECTIVES AGENTS 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013
ANTICANCER CHEMOTHERAPY 2024/2025 2023/2024 2022/2023 2021/2022
BODY SYSTEM & THERAPEUTICS IV: GIT & HEPATOBILIARY SYSTEMS 2024/2025 2023/2024 2022/2023 2021/2022
BODY SYSTEM & THERAPEUTICS VI : CENTRAL NERVOUS SYSTEM 2024/2025 2023/2024 2022/2023
BODY SYSTEM I : CARDIOVACULAR & HAEMATOLOGY 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013
BODY SYSTEM II : RESPIRATORY & URINARY SYSTEM 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013
BODY SYSTEM III : MUSCULOSKELETAL & SENSORY ORGANS 2018/2019 2017/2018 2016/2017 2013/2014
BODY SYSTEM IV: GASTROINTESTINAL &HEPATOBILIARY SYSTEMS 2020/2021 2019/2020 2018/2019 2017/2018
BODY SYSTEM V : ENDOCRINE & REPRODUCTIVE SYSTEMS 2019/2020 2017/2018 2016/2017 2015/2016 2014/2015 2012/2013
BODY SYSTEM VI : CNS 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013
DRUG ABUSE 2024/2025 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013
FINAL YEAR RESEARCH PROJECT 2024/2025 2023/2024 2022/2023
FUNDAMENTALS OF MEDICINAL CHEMISTRY 2024/2025 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013
HERBAL MEDICINE 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017
RESEARCH PROJECT 1 2020/2021 2019/2020 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014
RESEARCH PROJECT 2 2020/2021 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015
RESEARCH PROJECT-LITERATURE SEARCH 2019/2020 2017/2018 2016/2017 2015/2016 2014/2015 2013/2014 2012/2013


Supervision


Evaluation Of Anti-Diabetic Activities And Toxicity Of Psychotria Malayana Jack Leaves And Characterization Of Its Bioactive Compounds.
Ph.D Completed 2022 Co-supervisor
Development Of Resiquimod Loaded Nanosponges Based Topical Gel Formulation For Actinic Keratosis Treatment .
Ph.D In Progress Co-supervisor
Synthesis, Biological And Computational Studies Of Functionalized Chromone-Based Compounds As Potential Anticancer Agents.
Ph.D In Progress Co-supervisor
Investigating The Involvement Of Kappa Opioid Receptor In Mediating Relapse Related To Morphine/Methamphetamine (Poly-Drug) Dependence Using An Immunohistochemistry Technique.
Master Completed 2018 Main Supervisor
The Use Of Buprenorphine / Naltrexone Combination Treatment In Attenuating Relapse To Morphine / Methamphetamine Polydrug-Dependence In Mice.
Master Completed 2017 Main Supervisor
Development Of Essential Oil Nanoemulsion As Potential Topical Therapeutics For Skin Cancer.
Master In Progress Co-supervisor


Research Projects


Completed
2021 - 2024 Perspective of Pharmacists and Patients Towards Patient-Centered Mental Health Pharmacy Services
2021 - 2023 Transferring Knowledge on Quality Use of Medicines to Staff of Pertubuhan Komited Malaysia (KOMITED) in Pahang: Towards Improving Health Literacy during COVID-19 Pandemic.
2019 - 2022 Identification of alpha-glucosidase inhibitors from Psychotria malayana Jack leaf using multi-platform metabolomics approach and protein-ligand interaction with molecular docking in treating diabetes mellitus
2014 - 2018 Clinical Safety and Efficacy Evaluation of Ibogaine as an Anti-Addictive Treatment in Patients with Opioid Addiction
2014 - 2018 Synthesis and Mechanistic Evaluation of Orvinol Analogues as Potential Anti-Relapse to Morphine/ Methamphetamine Dependence
2013 - 2018 Synthesis, Mechanistic And Biological Evaluation Of Novel Bis-Sydnone Styrylketones As Antiproliferative And Antioxidant Agents
2012 - 2015 Sintesis analog dan modifikasi struktur mitragynine untuk mengkaji perkaitan di antara stuktur mitragynine dengan kesan psikoaktif drug
On-Going
2023 - Present A Feasibility Study on the Development of the Medical Cannabinoid Industry in Malaysia
2021 - Present Investigation on Formulation Parameters of Essential Oil Nanoemulgel as a Potential Therapeutics for Topical Skin Cancer


Publications


Articles

2024 Evaluation of the cytotoxic activity of essential oils from Malaysian herbal plants against A375 and A431 skin cancer cell lines. Asia Pacific Journal of Molecular Biology and Biotechnology, 32 (4) pp. 55-62
2024 Team experiential learning through community services delivery at private drug rehabilitation centres by university students: focus group discussion. Journal of Pharmacy, 4 (1) pp. 12-22
2022 Preventing oversight on medical Cannabis legislation in Malaysia: analysis of risks, benefits and regulation requirements.. Journal of the Malaysian Parliament, 2 () pp. 248-273
2021 GC-MS- and NMR-based metabolomics and molecular docking reveal the potential alpha-glucosidase inhibitors from psychotria malayana jack Leaves. Pharmaceuticals, 14 (10) pp. 1-29
2021 Rapid analysis of alpha-glucosidase inhibitory activity of Psychotria Malayana jack leaf applying infrared fingerprinting. International Journal of Allied Health Sciences (IJAHS), 5 (1 Special Issue) pp. 2144-2144
2020 Alpha-glucosidase inhibitory effect of psychotria malayana jack leaf: A rapid analysis using infrared fingerprinting. Molecules, 25 (18) pp. 1-11
2020 Characterization of α-glucosidase inhibitors from psychotria malayana jack leaves extract using LC-MS-based multivariate data analysis and in-silico molecular docking. Molecules, 25 (24) pp.
2017 Distinct role of kappa opioid receptor in attenuating relapse to morphine/methamphetamine (polydrug) dependence. British Journal of Pharmacy, 2 (2) pp. S21-22S
2017 The crucial role of nociceptin opioid peptide (NOP) receptor in attenuating relapse to morphine/methamphetamine (poly-drug) addiction in mice. Research Journal of Pharmacy and Technology, 10 (12) pp. 4488-4550
2017 Upregulation of kappa opioid receptor system and its association with relapse to morphine/methamphetamine (poly-drug) addiction. Research Journal of Pharmacy and Technology, 10 (12) pp. 4488-4550
2016 Kappa antagonist to prevent drug relapse: does stage in addiction cycle matter?. International Medical Journal Malaysia, 15 (Supplement issue) pp. 67-67
2014 A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm. Addiction Biology, 19 (4) pp. 575-586
2014 Evaluating the potential of buprenorphine to reduce relapse to morphine/methamphetamine addiction. Malaysian Journal of Pharmacy, 1 (11) pp. 199-199
2014 Selectively promiscuous opioid ligands: discovery of high affinity/low efficacy opioid ligands with substantial nociceptin opioid peptide receptor affinity. Journal of Medicinal Chemistry, 57 () pp. 4049-4057
2012 A single compound alternative to A Buprenorphine/Naltrexone combination to prevent relapse to drug addiction. British Journal of Clinical Pharmacology, 73 (6) pp. 1004-1004
Conference or Workshop Items

2022 Synthesis of flavone-based compounds as ros-dependent apoptosis inducers in colorectal cancer. In: International Conference on Pharmaceutical Sciences ICOPS@IIUM2022, 08-09 August 2022, IIUM, Kuantan.,
2021 LC-MS-based metabolomics and molecular docking to characterize α-glucosidase inhibitors from Psychotria Malayana Jack leaves extract. In: at the Asian Symposium on Medicinal Plants and Spices XVII (2021) – Virtual Conference,
2020 Rapid investigation of Αlpha-Glucosidase inhibitory activity of Psychotria Malayana Jack leaf using infrared fingerprinting. In: International Research Conference on Pharmaceutical and Allied Science 2020,
2018 Low-dose methamphetamine addiction induced opioid receptor sensitization in polydrug-dependent mice. In: Regional Conference on Science Technology & Social Sciences (RCSTSS2016),
2018 The crucial roles of nociceptin opioid peptide (NOP) receptor in attenuating relapse in morphine/methamphetamine (poly-drug) dependence model. In: 1st MYPSA National Pharmacy Research Competition (NPRC) 2018,
2015 Anti-stress properties of buprenorphine: a better choice for stress-induced relapse to drug addiction. In: International Conference on Addiction Science (iCAS 2015),
2015 Priming dose of morphine/methamphetamine combination induced stereotyped behavior in morphine/methamphetamine-dependent mice. In: International Conference on Biomedical & Health Sciences Research (ICBHSR 2015),
2015 The effect of dose on the intensity of dependence in morphine-dependent mice. In: Health and Pharmaceutical Sciences Undergraduate Research Symposium,
2015 The influence of duration of confinement towards morphine dependence intensity in conditioned place preference (CPP) model. In: Health and Pharmaceutical Sciences Undergraduate Research Symposium,
2015 The pyrrolidine ring and its relation with the psychoactivity of mitragynine. In: International Conference on Natural Products 2015 (ICNP 2015),
Monograph

2018 Synthesis, mechanistic and biological evalution of novel bis-sydnone styrylketone as antiproliferative and antioxidant agents. In: ,