Fakulti

Fakulti

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


Yumi Zuhanis Has-Yun Bt. Hashim
Associate Professor

  • INTERNATIONAL INSTITUTE FOR HALAL RESEARCH AND TRAINING
  • IIUM Gombak Campus
  • yumi@iium.edu.my
  • 5591

Print CV Email Me

Staff Detail


  • Doctor of Philosophy - Doctor of Philosophy, University of Ulster
  • Master of Engineering (Bioprocess) - Masters Degree, Universiti Teknologi Malaysia (UTM)
  • Bachelor of Biomedical Sciences (Hons.) - Bachelor Degree, Universiti Kebangsaan Malaysia (UKM)
  • Medical And Health ~ Medical And Health Sciences ~ Nutrition (Clinical and Public Health Research) ~ Nutrition Related Chronic Diseases - Mammalian cell culture bioprocessing; Phytochemical processing for health benefits
  • Medical And Health ~ Medical And Health Sciences ~ Pharmacy ~ Other Pharmacy n.e.c. - Mammalian cell culture bioprocessing Phytochemical processing for health benefits
  • 2005 - 2020 Fellow, Institute of Biomedical Sciences (IBMS)
  • 2020 - 2020 , INFAD, USIM
  • 2020 - 2020 , Chiang Mai University, Thailand
  • 2016 - 2019 Member, Young Scientist Network-Akademi Sains Malaysia
  • 2016 - 2019 Member , Young Scientist Network-Akademi Sains Malaysia
ARTIFICIAL TISSUE ENGINEERING 2016/2017 2017/2018
BIOTECHNOLOGY ENGINEERING LAB IV 2009/2010 2010/2011 2011/2012
CELL AND MOLECULAR BIOLOGY 2002/2003
CELL AND TISSUE ENGINEERING 2009/2010 2010/2011 2011/2012 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018
ENGIN. ASPECT OF ANIMAL & PLANT CELL CULTURE 2008/2009 2009/2010 2015/2016 2016/2017
GENOMICS AND FUNCTIONAL GENOMICS 2009/2010 2010/2011 2011/2012 2013/2014
NATURAL PRODUCTS,NUTRACEUTICALS & FUNCT.FOODS 2009/2010 2010/2011 2011/2012 2012/2013 2013/2014 2015/2016
SEMINAR 2014/2015 2019/2020
In Progress
2020 - Present Halal Pharmaceutical, Cosmetic and Personal Care Products
2019 - Present Geo-tourism Destination (GTD) Framework Based on Sustainable Development Goals and Maqasid Shariah
2019 - Present Revealing Agarwood-based Prescription(s) Documented in Malay Medical Manuscripts
2019 - Present Deciphering the mechanism of action of polymyxins on pentose phosphate pathway metabolism in Acinetobacter baumannii in discovering novel antibiotic targets
2019 - Present Dyes Adsorption Using Hybrid Aerogel-Based Cellulose Nanocrystal Isolated From Palm Oil Biomass
2019 - Present Bioactive compounds of A.malaccensis leaf and their mechanistic roles in inflammation and immunomodulation in zebrafish model
2019 - Present Potensi Ekstrak Mentah dan Minyak Gaharu dari Spesis Aquilaria Subintegra sebagai Bahan Anti-Kanser pada Sel Kanser Payudara MCF7
2018 - Present Synergistic killing of novel combinations of `old? polymyxin drug and medicinal plant extracts targeting Gram-negative bacteria
2018 - Present Investigation of Azafluorenone Compounds from Alphonsea SPP Against Breast Cancer Cell
2018 - Present Antibacterial activity of phenolic compounds from Carica papaya seed extract as food preservative.
2018 - Present Synergistic killing of novel combinations of `old? polymyxin drug and medicinal plant extracts targeting Gram-negative bacteria
2017 - Present Investigation of Chemical Composition of Alphosea Cylindrica (Annonceae) and its Potential Against MCF-7 Breast Cancer Cells
2017 - Present Fractionation and partial purification of active compounds from agarwood branch extract responsible for the cytotoxic/anticancer activity
2016 - Present Development of a Parallel biosensing system for personalized and pointof-care chemotherapy treatment
2015 - Present Lung Cancer Volatile Bio-marker Detection Using Novel Nanosensor Array
2015 - Present The Effect of Direct Irradiation of Excited Gas Discharge Using Micro Hollow Plasma To Skin Cancer Cells For Acceleration of Apoptosis
2006 - Present Bio-Process and Molecular Engineering Research Unit (BPMERU)
2006 - Present New Name: Bio-Process and Molecular Engineering Research Unit (BPMERU) Biomolecular Engineering Research Unit (BioMERU)
Completed
2018 - 2018 Investigation of Azafluorenone Compounds from Alphonsea SPP Against Breast Cancer Cell
2017 - 2018 Investigation of Chemical Composition of Alphosea Cylindrica (Annonceae) and its Potential Against MCF-7 Breast Cancer Cells
2017 - 2019 Fractionation and partial purification of active compounds from agarwood branch extract responsible for the cytotoxic/anticancer activity
2016 - -1 Investigation of Oxoaporphine Compounds from Platymitra Siamensis Craib (Annonaceae)as Anticancer Agent
2016 - 2018 Investigation of Oxoaporphine Compounds from Platymitra Siamensis Craib (Annonaceae)as Anticancer Agent
2016 - 2019 Development of a Parallel biosensing system for personalized and pointof-care chemotherapy treatment
2015 - 2018 Characterization of Halal and Non-Halal Animal Bones As Raw Material for Gelatin and Gelatin Based Products
2015 - 2019 The Effect of Direct Irradiation of Excited Gas Discharge Using Micro Hollow Plasma To Skin Cancer Cells For Acceleration of Apoptosis
2014 - 2018 Extraction of Gaharu Oil from Aquilaria Malaccensis using Subcritical Extraction Process
2013 - 2015 Transferring Knowledge and Skill on Halal Consumerism to the Orang Asli Community
2013 - 2016 Gene Expression Study of Cytotoxic Properties of Agarwood Branch Extract
2012 - 2015 Proof of Concept for a Novel Real Time, Hardware base Cancer Chemotherapeutics Kit Using MEMS Biosensor
2012 - 2015 Hardware Implementation of a Novel Impedance Spectroscopy System for Cancer Cell Studies
2012 - 2015 Discovery of the Primary and Secondary Metabolites Flux Distribution During Cell Growth of Ficus deltoidea Cell Suspension Culture
2012 - 2013 Comparison of Extraction Method for IGFBP-3 Removal from CHO-K1 Spent Media
2012 - 2015 Isolation and Characterization of Bacterial Strain Producing L-Asparaginase from Local Hot Spring
2012 - 2013 Investigation of Allium Sativum L.(GARLIC) as an alternative source for glutathione and cysteine production.
2012 - 2016 Application of cDNA Microarray for Study of Halal vs Haram Fat Subtances in HaCat Human Keratinocyte Cells
2011 - 2014 Inoculant Development and Studies of Health Beneficial Effects Gaharu
2011 - 2012 Development Of New Media Formulation For The Improvement Of Recombinant Protein Expression In E.Coli
2011 - 2012 Optimization of Process Conditions for Extraction of Xanthine Oxidase Inhibitor form Potential Malaysian Medicinal Plant
2011 - 2013 Growth Kinetics Study on MCF-7 Breast Cancer Cells Treated with Recombinant Bromelain
2011 - 2011 Indentification Of Microbes Cocktail In Inoculants For Agarwood Resin (Gaharu) Formation And Production By Phenotyping And Genotyping Methods
2011 - 2015 Upscaling of Gelatin Coated Microcarrier Beads Fabrication by Using Ultraviolet/Ozone (UVO) system
2011 - 2016 Development of GCMS-based Metabolomis (Global Metabolite Analysis)Platform/Tool Mammalian Cell Bioprocessing
2011 - 2012 Extraction of Plant Material for Discovery Anti-Cancer Properties
2010 - 2012 Investigation of Effects of Different Media on CHO Cell Growth and Production of IGFI
2009 - 2012 Production of L-cysteine from Various Parts of Garlic Plant"
2009 - 2012 Global Metabolite Analysis of CHO Cells Cultured in T-Flasks and Bioreactor using Gas Chromatography-Mass Spectrometry
2009 - 2012 Halal Certification training for Main Kazakhstan
2009 - 2012 Study on the Mode of Action of Tomato Leaves Extract for its anti-Inflammatory Activity in Murine Macrophages RAW264.7 Cell
2009 - 2012 Studies on Effect(s ) of Glutamine and/or Serum on CHO Cell Growth in Bioreactor Culture Focusing on the Insulin-like Growth Factor (IGF) Pathway
2006 - 2013 International Institute for Halal Research and Training (INHART)
19 Februari 2014 Gold medal in IIUM Research, Invention and Innovation Exhibition (IIRIE). IIUM - University level.
07 November 2013 Bronze medal in PECIPTA'13 (International Conference and Exposition on Invention of Institutions of Higher Learning. PECIPTA (Malaysia) - International level.
07 November 2013 Gold medal and Leading Innovation Award in PECIPTA'13 (International Conference and Exposition on Invention of Institutions of Higher Learning). . PECIPTA (Malaysia) - International level.
07 November 2013 Silver medal in PECIPTA'13 (International Conference and Exposition on Invention of Institutions of Higher Learning). PECIPTA (Malaysia) - International level.
31 Oktober 2013 Gold medal in the 65th iENA International Trade Fair "Ideas-Inventions-New products (IENA). IENA - International level.
07 Mei 2013 Silver medal in the 24th International Invention, Innovation & Technology Exhibition (ITEX). ITEX - International level.
04 April 2013 Top-5 exhibitor in the Halal Innovation Products Category at the World Halal Week Conference 2013 . HDC - International level.
21 Disember 2010 Best Library Partner 2010. IIUM Library - University level.
16 Oktober 2010 BIOINNO AWARDS (BIOMALAYSIA 2010) (Statistical Optimization of Medium Components to Improve Recombinant Phytase Production in E.coli Dha. MALAYSIAN ASSOCIATION OF RESEARCH SCIENTIST AND BIOTECH CORP - National level.
16 Februari 2010 BRONZE MEDAL FOR MALAYSIA TECHNOLOGY EXPO 2010 (Special Oils for Halal and Safe Cosmetics). Malaysia - National level.
16 Februari 2010 MARQUIS WHO'S WHO IN MEDICINE AND HEALTH CARE. MARQUIS - International level.
Article
2014 Pathway analysis of genes affected in MCF-7 breast cancer cells treated with recombinant bromelain. Journal of Pure and Applied Microbiology , 8 (s.ed 1) pp.681-689
2014 Development and improvement of anti-gout property from aqueous-methanol extract of morinda elliptica using central composite design. Advances in Environmental Biology , 8 (3) pp.734-743
2014 Virgin olive oil phenolics extract inhibit invasion of HT115 human colon cancer cells in vitro and in vivo. Food and Function , 5 (7) pp.1513-1519
2014 Ultrasonic-assisted extraction of thiols from garlic bulbs. Advances in Environmental Biology , 8 (3) pp.725-728
2014 Effects of glutamine and serum on IGF- dependent cho-K1 cell growth in T-Flask. Advances in Environmental Biology , 8 (3 ( Special Issue )) pp.831-837
2014 Analysis of chemical compounds of agarwood oil from different species by gas chromatography mass spectrometry (GCMS). IIUM Engineering Journal , 15 (1) pp.55-60
2014 Comparison of two total RNA extraction protocols from CHO-K1 cells for RT-PCR: cutoff cost for researchers. IIUM Engineering Journal , 15 (1) pp.33-39
2014 Gene expression analysis in MCF-7 breast cancer cells treated with recombinant bromelain. Applied Biochemistry and Biotechnology , 173 (7) pp.1618-1639
2014 Screening of anticancer activity from agarwood essential oil. Pharmacognosy Research , 6 (3) pp.191-194
2014 Cytokinetics study on MCF-7 cells treated with commercial and recombinant bromelain. Asian Pacific Journal of Cancer Prevention , 14 (11) pp.6709-6014
2014 Carotenoid content in different locality of pumpkin (Cucurbita moschata) in Malaysia. International Journal of Pharmacy and Pharmaceutical Sciences , 6 (Supp 3) pp.29-32
2013 Metabolomics profiling of extracellular metabolites in CHO-K1 cells cultured in different types of growth media. Cytotechnology , 65 (4) pp.577-586
2013 Microarray and quantitative PCR analysis of gene expression profiles in response to treatment with tomato leaf extract in MCF-7 breast cancer cells. Asian Pacific Journal of Cancer Prevention , 13 (12) pp.6319-6325
2012 A rapid method for large sample number extraction of proteins from mammalian cells. Regenerative Research , 1 (2) pp.49-55
2012 Serum in mammalian cell culture: weighing the challenges of bioprocessing, ethics and animal welfare. Advances in Natural and Applied Sciences , 6 (5) pp.596-600
2012 Scheme of obtaining ß-carotene standard from pumpkin (Cucurbita moschata) flesh . International Food Research Journal , 19 (2) pp.531-535
2011 Phytochemical screening for antibacterial activity of potential Malaysian medicinal plants. African Journal of Biotechnology , 10 (81) pp. 18795-18799
2011 Preliminary investigation of Myo-Inositol Phosphates produced by Asuia279phytase on Mcf-7 cancer cells.. IIUM Engineering Journal , 12 (4) pp.141-151
2011 Chinese hamster ovary (CHO-K1) cells expressed native insulin-like growth factor-1 (IGF-1) gene towards efficient mammalian cell culture host system . African Journal of Biotechnology , 10 (81) pp.18716-18721
2011 Determination of IGF-1-producing CHO-K1 growth phases using GCMS-based global metabolite analysis. IIUM Engineering Journal , 12 (4) pp.89-98
2011 Safe=(Halal + Toyyebah): personal care products, please! Muslim consumers are still facing dilemma in choosing halal cosmetics.... Halal Pages 2011/2012 pp.60-65
2011 Preliminary investigation of MYO-INOSITOL phosphates produced by ASUIA279PHYTASE on MCF-7 cancer cells. IIUM Engineering Journal , 12 (4) pp.1-11
2010 The beautiful Halal. Halal Pages 2010/2011 pp.20-24
2010 Effects of menstrual cycle phase on metabolomic profiles in premenopausal women. Human Reproductive , 25 (4) pp.949-956
2010 Comparing BRIN-BD11 culture producing insulin using different type of microcarriers. Cytotechnology , 62 pp.423-430
2009 Halal cosmeceuticals: the vogue and the vague. Halal Pages 2009/2010 pp.50-55
2008 Comparison of alcohol free GSH production by ultrasonic and homogenizing method . Iranian Journal of Chemistry & Chemical Engineering , 27 (4) pp.107-113
2008 Monoclonal antibody production: media optimization for enhancement the cell viability of hybridoma cell. Asian Journal of Scientific Research , 1 (5) pp.525-531
2007 Inhibitory effects of olive oil phenolics on invasion in human colon adenocarcinoma cellsin vitro. International Journal of Cancer , 122 (3) pp.495-500
2005 Comparison studies among the methods used in isolating the GSH from baker yeast. Journal of Applied Sciences , 5 (1) pp.151-154

Conference or Workshop Item

2014 Chitosan microcarriers in mammalian cell culture. In: International Conference on Biological, Chemical and Environmental Sciences (BCES-2014)
2014 Anti-cancer activity of un-inoculated agarwood branch against MCF-7 breast cancer cells. In: 5th International Conference on Biotechnology for the Wellness Industry
2013 Anticancer potential of agarwood distillate. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Development of polystyrene microcarrier by an emulsion solvent evaporation process. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2013
2013 Pathway analysis of genes affected in MCF-7 breast cancer cells treated with recombinant bromelain. In: 3rd International Conference on Biotechnology Engineering 2013 (ICBioE 2013)
2013 Fabrication of gelatin coated polycaprolactone (PCL) microspheres for cell culture application. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2013
2013 Agarwood distillate: Safe for oral consumption. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Novel carotenoids from local pumpkin (Cucurbita moschata): Effect of storage and temperature in post harvest handling. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2013
2013 GCMS-based global metabolite analysis approach distinguishes CHO-K1 cells cultured in different levels of serum and glutamine. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 The study of cell attachment and spreading on polyaniline and gelatin using electric cell-substrate impedance sensing. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Ultrasonic-assisted extraction of thiols from garlic bulb. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Health benefits of gum arabic as natural halal food ingredient and emulsifying agent. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Effect of season and storage period time towards accumulation of individual carotenoid content in pumpkin flesh (Cucurbita moschata). In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Identification of microbes in inoculants for agarwood (gaharu) formation using molecular biological techniques. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Production of natural carotenoid pigments from pumpkin as Halal food colorants and Active Pharmaceutical Ingredients (API). In: International Conference And Exposition On Invention Of Institutions Of Higher Learning (PECIPTA 2013)
2013 Effects of glutamine and serum on IGF-I dependent CHO-K1 cell growth in T-flask. In: 3rd International Conference on Biotechnology Engineering 2013 (ICBioE 2013)
2013 Studies on the process condition that affect the size of polystyrene microcarrier by an emulsion solvent evaporation process. In: 3rd International Conference on Biotechnology Engineering (ICBIoE 2013
2013 Gaharu (agarwood) distillate-incorporated roselle health drink. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2013
2013 Gaharu (Agarwood, aquilaria subintegra): A potential source of anticancer and antiinflammatory compounds. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2013
2012 Antimicrobial activities of agarwood A.subintegra leaves extract.. In: 11th International Annual Symposium on Sustanainability Science and Management, UMTAS (2012)
2012 Screening of anticancer activity from agarwood essential oil.. In: Malaysian International Conference on Trends in Bioprocess Engineering, MICOTribe (2012)
2012 Metabolite profiles of agarwood leaves aqueous extracts.. In: 4th Australasian Metabolomics Symposium 2012,
2012 Carotenoid content in pumpkin from different locality in Malaysia. In: PharmaTech 2012 : International Conference and Exhibition on Pharmaceutical, Nutraceutical and Cosmeceutical Technology
2011 Optimization of process condition for isolation of Glutathione (GSH) from garlic bulbs. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2011
2011 Optimization of Glutathione (GSH)production from selected Malaysian local fruits by ultrasonic method. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2011
2011 Serum in mammalian cell culture: weighing the challenges of bioprocessing, ethics and animal welfare. In: 2nd International Conference on Professional Ethics and Education in Engineering 2011 (ICEPEE'11)
2011 Effects of different types of growth media on metabolite profiles (GCMS-based) of CHO-K1 cells expressing IGF-1 proteins. In: 2nd International Conference on Biotechnology Engineering (ICBioE 2011)
2011 Comparison of two total RNA extraction protocols from CHO-KI cells for RT-PCR: cut-off cost for researcher. In: The 3rd Curtin University Technology, Science and Engineering (CUTSE)
2011 Phytochemical Screening for Antibacterial Activity of Potential Malaysian Medicinal Plants. In: 2nd International Conference on Biotechnology Engineering (ICBioE 2011)
2011 GCMS-based global analysis as complementary tool: determination of CHO-K1 growth phases . In: 2nd International Conference on Biotechnology Engineering (ICBioE 2011)
2011 Scheme of obtaining ß-carotene standard from pumpkin (Cucurbita moschata) flesh . In: 2nd International Conference on Biotechnology Engineering (ICBioE 2011)
2010 IGF-1 protein expression in cultured CHO cells. In: 3rd IIUM-iCAST International Conference on Advancement in Science and Technology
2010 Special oils for halal and safe cosmetics. In: IIUM Research, Invention and Innovation Exhibition 2010 (IRIIE2010).
2010 Pathway analysis and primer design of selected genes up-regulated by Olive Oil Phenolics (OVP) treatment in colon cancer cells. In: 3rd International Conference on Advancement in Science and Technology (iCAST 2010)
2009 A mechanistics investigation into the anti-invasive effects of olive oil phenolics. In: INTERNATIONAL CONFERENCE (ICBWI-INTRACOM '09)
2009 Special oils for halal cosmetics. In: 3rd IMT-GT International Symposium on Halal Science and Management 2009
2009 The effects of different stages of the menstrual cycle on the the metabolomic profiles of urine and plasma in healthy women. In: Metabomeeting 2009
2004 ISOLATION OF GSH FROM BAKER YEAST BY MECHANICAL METHODS. In: Regional Symposium on Chemical Engineering (RSCE 2004)

Book

2013 Halal all that you need to know (vol 1). Institut Terjemahan & Buku Malaysia Berhad (ITBM) . ISBN 987-967-430-010-4

Book Section

2011 In vitro assay for investigating potential anti-cancer agents targeting at metastatic level. In: Experimental methods in modern biotechnology IIUM Press . ISBN 9789670225869 , pp.115-122
2011 The growth culture of BRIN-BD11 producing insulin in different type of microcarriers . In: Recent Development of Microcarrier for Cell Culture Engineering IIUM Press . ISBN 9789674180096 , pp.97-109
2011 Serum free medium . In: Introduction to cell culture for engineering IIUM Press . ISBN 9789674180713 , pp.47-57
2010 Olive oil and its phenolic components and their effects on early- and late-stage events in Carcinogenesis. In: Olives and Olive Oils in Health and Disease Prevention Elsevier, Inc. . ISBN 9780123744203 , pp.1005-1012