Researchers

Researchers

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Mohammad Syaiful Bahari Bin Abdull Rasad
Associate Professor

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Staff Details

Area of Specialisation

  • Biotechnology ~ Biotechnology ~ Molecular Biology ~ Molecular and Structural Biology

Teaching Responsibilities

BASIC PATHOLOGY 2018/2019 2019/2020 2020/2021
BIOCHEMISTRY II 2011/2012
CELL & TISSUE CULTURE 2019/2020
DEVELOPMENTAL PSYCHOLOGY FOR HEALTH SCIENCE 2013/2014
EMBRYOLOGY & ONCOLOGY 2013/2014
FAMILY MANAGEMENT AND PARENTING 2011/2012 2012/2013 2013/2014 2017/2018 2018/2019 2019/2020
FINAL YEAR PROJECT I 2012/2013
FINAL YEAR PROJECT II 2011/2012 2012/2013
FINAL YEAR RESEARCH PROJECT 1 2016/2017 2019/2020
FINAL YEAR RESEARCH PROJECT 2 2017/2018
FUNCTIONAL BIOCHEMISTRY 2009/2010 2010/2011 2011/2012
GENES AND NUTRITION 2018/2019 2019/2020 2020/2021
GENETICS 2013/2014 2014/2015 2015/2016 2016/2017 2017/2018
HAEMATOLOGY AND ONCOLOGY 2011/2012 2012/2013 2013/2014
HUMAN GENETIC 2012/2013
HUMAN GENETICS 2011/2012 2012/2013 2013/2014
INDUSTRIAL PHARMACY 2014/2015
INTRODUCTION TO BIOMEDICAL LABORATORY SCIENCES 2012/2013 2013/2014 2014/2015 2015/2016 2016/2017
LEADERSHIP AND MANAGEMENT 2011/2012 2012/2013 2014/2015 2015/2016
MEDICAL BIOTECHNOLOGY 2004/2005
MOLECULAR AND CELL BIOLOGY 2004/2005
MOLECULAR BIOLOGY 2011/2012 2013/2014
MOLECULAR BIOLOGY & CYTOGENETIC TECHNIQUES 2014/2015 2015/2016 2017/2018 2018/2019
MOLECULAR BIOLOGY TECHNIQUES 2019/2020 2020/2021
MOLECULAR CANCER RESEARCH 2019/2020 2020/2021
Molecular Biology 2012/2013 2015/2016
NANOMEDICINE 2020/2021
NANOMEDICINE IN HEALTHCARE 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019
NUTRITION AND GENES 2010/2011 2012/2013 2013/2014
OCULAR GENETICS 2018/2019 2019/2020 2020/2021
PRINCIPLES OF GENETICS 2017/2018 2018/2019 2019/2020 2020/2021
PRINCIPLES OF MICROBIOLOGY 2012/2013
RESEARCH METHODOLOGY 2015/2016 2016/2017
RESEARCH METHODOLOGY (MHSC) 2015/2016 2016/2017
RESEARCH PROJECT 1 2020/2021
RESEARCH PROJECT 2 2020/2021

Research Projects

In Progress
2019 - Present Identification of new inhibitor of Protein Arginine Deiminase 4 (PAD4) by consensus docking and biological assay to treat Rheumatoid Arthritis
2017 - Present Elucidating the anti-cancer Mechanism of thymoquinone nanoparticles involving the MAPK signaling pathway in zebrafish xenografts of colonic and melanoma cancers. in vitro & in vivo study
2013 - Present NEW NAME: RESEARCH CLUSTER OF MOLECULAR AND CELLULAR BIOLOGY OF IIUM (i-MoleC) Human Molecular And Cellular Biology (HMCB)
2013 - Present MOLECULAR AND CELLULAR BIOLOGY OF IIUM Research Unit (i-MOLEC)
Completed
2015 - 2018 Effect of Thymoquinone PLGA Nanoparticles on the Expression of Collagenase Matrix Metalloproteinases and Its Anti-proliferative & Anti-invasive Properties In The A375 Malignant Melanoma Cell Line In Vitro: Efficacy Of a Prophetic Medicine Through A Scientific Approach
2013 - 2016 Understanding the Anti-Proliferative Mechanisms of Malaysian Porcupine Bezoar on Breast, Colon, Prostate and Tongue Cancer Cell Lines
2011 - 2013 In Vitro Anticancer Activity of Underutilized Fruit Baccaurea Angulata (Belimbing Dayak) on Several Cancer Cell Lines
2011 - 2014 Biochemical Characterization for Matrix Metalloproteinases (Collagenases) Regulation via Novel CTCF/YB-1 Protein Interaction for Potential Targeted Therapy of Human Cancers
2011 - 2014 RU 2011 -In vitro anticancel activityof underutilized Melastoma malabathricum L (senduduk) on several cancer cell lines.
2010 - 2012 Cell/Tissue Culture Research and Technology From Islamic Perspectives

Publications

Article
2020 Response surface optimisation and antioxidant characterisation of high antioxidant soft jelly prepared from Baccaurea angulata fruit juice and Trigona sp. honey using central composite design. International Food Research Journal , 27 (3) pp.454-464
2020 In vitro antibacterial effect of the leaf extract of Murraya koenigii on cell membrane destruction against pathogenic bacteria and phenolic compounds identification. European Journal of Integrative Medicine , 33
2019 Matrix metalloproteinases in cancer biology: a review. International Medical Journal Malaysia (IMJM) , 18 (2) pp.147-152
2019 In-vitro cytotoxicity of Trigona itama honey against human lung adenocarcinoma epithelial cell line (A549). European Journal of Integrative Medicine , 30 pp.1-8
2019 Identification and quantification of quercetin, a major constituent of Artocarpus altilis by targeting related genes of apoptosis and cell cycle: in vitro cytotoxic activity against human lung carcinoma cell lines. Nutrition and Cancer pp.1-14
2018 Effect of shRNA mediated silencing of YB-1 protein on the expression of matrix collagenases in malignant melanoma cell in vitro. Cells , 7 (1) pp.1-13
2017 A facile synthesis method of hydroxyethyl cellulose-silver nanoparticle scaffolds for skin tissue engineering applications. Materials Science and Engineering C , 79 pp.151-160
2017 Expression of collagenases matrix metalloproteinases and YB-1 oncogenic factor in malignant melanoma cancer cells and its regulation by stromal fibroblasts. International Journal of Cancer Research , 13 (1) pp.17-25
2017 Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response. International Journal of Polymeric Materials and Polymeric Biomaterials , 66 (3) pp.115-122
2016 Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities. European Journal of Nutrition , 55 (4) pp.1435-1444
2016 Porcupine bezoar exhibit as anti-cancer activities on human breast adenocarcinoma cells (MCF-7). JOURNAL OF BIOMEDICAL AND CLINICAL SCIENCES , 1 (Special Issue) pp.61-61
2016 Fabrication, characterization and in vitro biocompatibility of electrospun hydroxyethyl cellulose/poly (vinyl) alcohol nanofibrous composite biomaterial for bone tissue engineering. Chemical Engineering Science , 144 pp.17-29
2015 Evaluation of antioxidant, total phenol and flavonoid content and antimicrobial activities of artocarpus altilis (breadfruit) of underutilized tropical fruit extracts. Applied Biochemistry and Biotechnology , 175 (7) pp.3231-3243
2015 Expression of matrix metalloproteinase-13 in human skin melanoma cancer treated by Baccaurea angulata in vitro. Journal of Basic and Applied Research , 1 (1) pp.21-28
2015 Antioxidant activity and phenolic profile of various morphological parts of underutilised Baccaurea angulata fruit. Food Chemistry , 172 pp.778-787
2015 Electrospun hydroxyethyl cellulose nanofibers functionalized with calcium phosphate coating for bone tissue engineering. RSC Avances , 5 pp.29497-29504
2014 In vitro degradation study of novel HEC/PVA/collagen nanofibrous scaffold for skin tissue engineering applications. Polymer Degradation and Stability , 110 pp.473-481
2014 Cytotoxicity screening of melastoma malabathricum extracts on human breast cancer cell lines in vitro. Asian Pacific Journal of Tropical Biomedicine , 4 (7) pp.545-548
2014 Nanostructured material from hydroxyethyl cellulose for skin tissue engineering. Carbohydrate Polymers , 114 pp.238-245
2014 Improved cellular response of chemically crosslinked collagen incorporated hydroxyethyl cellulose/poly(vinyl) alcohol nanofibers scaffold. Journal of Biomaterials Applications pp.1-14
2013 Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro. The Open Conference Proceedings Journal , 4 pp.249-249
2013 Changes in the markers of atherosclerosis following administration of Belimbing dayak (Baccaurea angulata) fruit juice in experimental rabbits fed with cholesterol diet. International Journal of Advances in Agricultural & Environmental Engineering (IJAEE) , 1 (1) pp.151-154
2013 In vitro antioxidant properties of underutilized baccaurea angulata fruit. International Journal of Advances in Agricultural & Environmental Engineering (IJAEE) , 1 (1) pp.144-150
2010 In vitro evaluation of novel chitosan derivatives sheet and paste cytocompatibility on human dermal fibroblasts. Carbohydrate Polymers , 79 pp.1094-1100
2008 CTCF, YB-1, C-MYC and P53 expressions of established primary human hypertrophic scar and normal fibroblasts skin cells in response to novel chitosan derivatives sheet. Journal of Biotechnology , 136 (supplement) pp.S121
2008 The expression of Cytokeratin 6, involucrin, heat shock protein 47 and fibroblasts surface protein in primary cultured human skin in vitro: a model for skin immunocytochemistry. The Malaysian Journal of Medical Sciences , 15 (supp. 1) pp.121
2008 CTCF, YB-1, c-myc, and p53 expressions of primary human hypertrophic scar and normal fibroblast skin cells in response to novel chitosan derivatives sheet. Chinese Journal of Biotechnology , 24 (2) pp.2137-2139
2007 Biocompatibility of novel chitosan paste derivatives in cultured primary human skin fibroblasts in vitro. The Malaysian Journal of Medical Sciences , 14 (Supplement 1) pp.180-180

Conference or Workshop Item
2016 Porcupine bezoar exhibit cell cycle arrest through inhibiting cyclin /CDK1 complex and apoptosis mitochondria mediated dependent pathway in A549 cells. In: 3rd Pan-Asian Biomedical Science Conference 2016 (3rd PABSC)
2016 YB-1 gene expression in A375 malignant melanoma cells. In: 1st Allied Health Scientific Colloqium (AHSC 2016)
2014 Potential hypocholesterolemic and health benefitsof Baccaurea angulata fruit in hypercholesterolemic rabbits. In: K.A.H.S. Research Week 2014
2014 Antiatherosclerotic effect of Baccaurea angulate: an under-utilized fruit. In: K.A.H.S. Research Week 2014
2014 Evaluation of antioxidant, total phenolsand flavonoids content and antimicrobial activities of Artocarpus altilis (breadfruit) of underutilized tropical fruit extracts. In: International Health Conference IIUM 2014
2014 In vivo ctcf and yb-1 interaction with ap-1 site of matrix metalloproteinase 13 gene promoter in human malignant melanoma cell line. In: International Health Conference IIUM 2014
2013 In vivo antioxidant efficacy of Baccaurea angulata fruit extracts . In: 5th Global Summit on Medicinal and Aromatic Plants (GOSMAP-5)
2013 In vitro Antioxidant and Lipid Peroxidation inhibitory properties of Baccaurea angulata fruit extracts. In: 5th Global Summit on Medicinal and Aromatic Plants (GOSMAP-5)
2013 Characterization of collagenase 3 (MMP-13) expressions in skin melanoma, breast cancer and cervical cancer in vitro. In: 2013 2nd International Conference on Environment, Energy and Biotechnology (ICEEB 2013),
2013 Expression of matrix metalloproteinase-13 in human skin melanoma cancer treated by baccaurea angulata in vitro. In: 4th Malaysian Symposium on Biomedical Sciences 2013
2013 Preliminary screening of cytotoxic properties of Baccaurea angulata in several human cancer cell lines in vitro. In: International Conference on Medical and Health Sciences
2013 Characterization of Matrix Metalloproteinases (MMPs) and CTCF protein expressions in several human cancer cell lines in vitro. In: International Conference on Medical and Health Sciences
2012 The effects of in vitro treatment of melastoma malabathricum on fibroblast proliferation. In: 2012 2nd International Conference on Environment Science and Biotechnology (ICESB 2012)
2012 Potential anticancer properties of novel fiber from Baccaureas angulata (Belimbing Dayek). In: 3rd Exposition on Islamic Innovation 2012
2012 In vitro cytotoxicity effects of Baccaurea angulata on human breast cancer cell lines (MCF-7). In: 3rd Malaysian Symposium on Biomedical Sciences 2012
2011 Characterization of the CTCF and YB-1 protein-protein interaction by Novel Chitosan derivatives treatment in human skin. In: International Health Conference IIUM 2011
2011 Preliminary screening of anticancer activity using underutilized fruit Baccaurea angulata on breast cancer cell lines (MDA-MB-231). In: 3rd Malaysian Symposium on Biomedical Sciences 2012

Book
2013 Cell and tissue culture: research and technology from Islamic perspective. IIUM Press . ISBN 978-967-418-269-4

Book Section
2014 Tissue engineering: an Islamic perspective. In: Cell and Tissue Culture : Research and Technology from Islamic Perspective IIUM Press . ISBN 978-967-418-269-4 , pp.153-185
2014 Tissue engineering: an Islamic perspective. In: Cell and Tissue Culture : Research and Technology from Islamic Perspective IIUM Press . ISBN 978-967-418-269-4 , pp.153-185
2014 Basic techniques and research in cell culture: integration of Islamic approach. In: Cell and tissue culture research and technology from Islamic perspective IIUM Press . ISBN 978-967-418-269-4 , pp.61-80
2014 Diagnostic and therapeutic applications of cell and tissue culture from Islamic perspectives. In: Cell and tissue culture research and technology from Islamic perspective IIUM Press . ISBN 978-967-418-269-4 , pp.81-109
2013 Cell and tissue culture: an overview. In: Cell and tissue culture: research and technology from Islamic perspective IIUM Press . ISBN 978-967-418-269-4 , pp.23-52
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