Researchers

Researchers

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


Kamal Rullah
Assistant Professor

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Staff Details

Area of Specialisation

  • Natural Science ~ Chemical Sciences ~ Organic Chemistry ~ Medicinal Chemistry
  • Medical And Health ~ Medical And Health Sciences ~ Pharmacy ~ Medicinal Chemistry 84

Teaching Responsibilities

ANTI-INFECTIVE AGENTS 2020/2021 2021/2022 2022/2023 2023/2024
BODY SYSTEM & THERAPEUTICS III: MSK SYSTEM & SENSORY ORGANS 2021/2022 2022/2023 2023/2024
BODY SYSTEM III : MUSCULOSKELETAL & SENSORY ORGANS 2019/2020
COMPUTER AIDED DRUG DESIGN AND DISCOVERY 2019/2020
COMPUTER-AIDED DRUG DESIGN AND DISCOVERY 2020/2021 2021/2022 2022/2023 2023/2024
FINAL YEAR RESEARCH PROJECT 2022/2023 2023/2024
FUNDAMENTALS OF MEDICINAL CHEMISTRY 2019/2020 2020/2021 2021/2022 2022/2023 2023/2024
HERBAL MEDICINE 2019/2020 2020/2021
NUCLEAR PHARMACY 2020/2021 2022/2023 2023/2024
PHARMACEUTICAL INSTRUMENTAL ANALYSIS 2020/2021 2021/2022 2022/2023 2023/2024
PHARMACEUTICAL ORGANIC CHEMISTRY 2019/2020
RESEARCH PROJECT 1 2021/2022
RESEARCH PROJECT-LITERATURE SEARCH 2020/2021

Research Projects

In Progress
2021 - Present Encapsulation of Malaysian Patin Oil-loaded Alginate Microbeads Prototype for Supporting Children's Growth
2020 - Present Pharmacological Evaluation of a novel chloro-containing flavonoid molecule (KR-2001-KW) as an anticancer agent
2019 - Present Development and characterization of nanofibers patch containing nicotine using electrospinning: a novel approach as nicotine replacement therapy.
2019 - Present Development and characterization of nanofibers patch containing nicotine using electrospinning: a novel approach as nicotine replacement therapy.
Unknown - Present Pharmacological Evaluation of a novel chloro-containing flavonoid molecule (KR-2001-KW) as an anticancer agent
Unknown - Present Pharmacological Evaluation of a novel chloro-containing flavonoid molecule (KR-2001-KW) as an anticancer agent

Publications

Article
2021 Virtual screening-based identification of potent DENV-3 RdRp protease inhibitors via in-house usnic acid derivative database. Journal of Computational Biophysics and Chemistry , 20 (8) pp.797-814
2021 Biomedical application of responsive ‘smart’ electrospun nanofibers in drug delivery system: A minireview. Arabian Journal of Chemistry , 14 (7)
2021 In Silico Functional and Structural Insight of Prenylated Pyrazolocurcumin Derivative Associated with the PGE2 Inhibition through mPGES-1 Blocking. Materials Science Forum , 1025 pp.219-223
2020 Targeted delivery of 5-fluorouracil-1-acetic acid (5-FA) to cancer cells overexpressing epithelial growth factor receptor (EGFR) using virus-like nanoparticles. Scientific Reports , 10 (1)
2020 Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies. Bioorganic Chemistry , 94 pp.1-12
2019 Oestrogenic activity of mimosine on MCF‐7 breast cancer cell line through the ERα‐mediated pathway. Chemical Biology and Drug Design , 93 (3) pp.1-10
2019 Palladium‐catalysed cross‐coupling reactions for the synthesis of chalcones. Asian Journal of Organic Chemistry , 8 (8) pp.1174-1193
2019 Design and synthesis of a novel mPGES-1 lead inhibitor guided by 3D-QSAR CoMFA. Journal of Molecular Structure , 1196 pp.844-850
2019 Insights on the synthesis of asymmetric curcumin derivatives and their biological activities. European Journal of Medicinal Chemistry , 183
2018 Kajian dok molekul mengenai interaksi antara RNA-bergantung RNA polimerase virus denggi dan analog nukleosida = Molecular docking study of the interactions between dengue virus RNA-dependent-RNA polymerase and nucleoside analogues. Sains Malaysiana , 47 (3) pp.517-522
2018 Hits-to-lead optimization of the natural compound 2,4,6-trihydroxy-3-geranyl-acetophenone (tHGA) as a potent LOX Inhibitor: synthesis, structure-activity relationship (SAR) study and computational assignment. Molecules , 23 (10) pp.1-19
2018 Synthesis, biological evaluation and docking studies of aurone derivatives on Xanthine oxidase enzyme. Jurnal Sains Kesihatan Malaysia (JSKM) , 16 (1) pp.135-143
2017 Suppression of PGE2 production via disruption of MAPK phosphorylation by unsymmetrical dicarbonyl curcumin derivatives. Medicinal Chemistry Research , 26 (12) pp.3323-3335
2016 Effects of tocotrienols on insulin secretion-associated genes expression of rat pancreatic islets in a dynamic culture. Frontiers in Pharmacology , 7 pp.1-17
2016 Synthesis and effects of oxadiazole derivatives on tyrosinase activity and human SK-MEL-28 malignant melanoma cells. RSC Advances , 6 (76) pp.72177-72184
2016 Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines. Bioorganic & Medicinal Chemistry Letters , 26 (10) pp.2531-2538
2015 Probing the effects of fish oil on the delivery and inflammation-inducing potential of imiquimod. International Journal of Pharmaceutics , 490 pp.131-141
2015 Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives. Bioorganic & Medicinal Chemistry Letters , 25 (16) pp.3330-3337
2015 Molecular characterization, biological activity, and in silico study of 2-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-6-methoxy-4H-chromen-4-one as a novel selective COX-2 inhibitor. Journal of Molecular Structure , 1081 pp.51-61
2015 Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxideinhibitors. Medicinal Chemistry Communication , 6 pp.1069-1080
2014 Inhibition of prostaglandin E-2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation. Bioorganic & Medicinal Chemistry Letters , 24 (16) pp.3826-3834
2014 Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents. Molecules , 19 (10) pp.16058-16081
2014 Synthesis and docking studies of 2,4,6-trihydroxy-3-geranylacetophenone analogs as potential lipoxygenase inhibitor. Molecules , 19 (8) pp.11645-11659

Conference or Workshop Item
2019 Synthesis and SAR studies of new chromone derivatives as Inhibitors of PGE2 production. In: 1st Malaysian Association for Cancer Research (MACR) Scientific Conference (1st MSC) 2019

Book

Book Section
2020 Synthesis, In silico molecular docking modeling and pharmacophore mapping of (E)-3-(4-hydroxy-2,6-dimethoxyphenyl)-1-phenylprop-2-en-1- one as potential new inhibitor of microsomal prostaglandin E synthase-1. In: Industrial science and technology : symposium on industrial science and technology (SISTEC 2019) Trans Tech Publications Ltd . ISBN 978-303571664-1 , pp.247-252
2020 Synthesis, In silico molecular docking modeling and pharmacophore mapping of (E)-3-(4-hydroxy-2,6-dimethoxyphenyl)-1-phenylprop-2-en-1- one as potential new inhibitor of microsomal prostaglandin E synthase-1. In: Industrial science and technology : symposium on industrial science and technology (SISTEC 2019) Trans Tech Publications Ltd . ISBN 978-303571664-1 , pp.247-252
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