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Azrina Binti Md. Ralib
Associate Professor

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Dr Azrina Md Ralib obtained her Bachelor of Medical Science degree from the University of St. Andrews, UK and Bachelor of Medicine and Bachelor of Surgery (MBChB) degree from the University of Manchester, UK. Upon completion of her bachelor degrees, she returned to Malaysia for her housemanship training. She then joined the Department of Anaesthesiology and Intensive Care in 2002 as trainee lecturer, and started her anaesthesiology training at Universiti Sains Malaysia, Kubang Kerian. She graduated as Clinical Specialist in Anaesthesiology in 2006 with several awards to her name, including the ... show more

  • Postgraduate Diploma in Islamic Studies - Post Graduate Diploma, International Islamic University Malaysia
  • Doctor of Philosophy - Doctor of Philosophy, University of Otago
  • Master of Medicine (Anaesthesiology) - Masters Degree, Universiti Sains Malaysia (USM)
  • Bachelor of Medicine and Bachelor of Surgery - Bachelor Degree, University of Manchester
  • Bachelor of Science in Medical Science - Bachelor Degree, University of St Andrews
  • Medical And Health ~ Medical And Health Sciences ~ Clinical Medicine ~ Anaesthesiology - Anaesthesiology and Intensive Care
  • 2016 - 2018 , UITM Pulau Pinang
  • 2016 - 2018 , Informa Healthcare
  • 2013 - 2018 Member, National Specialist Registry
  • 2013 - 2017 , International Islamic University Malaysia
  • 2015 - 2017 Appointed University Panel Reviewer for the Fundamental Research Grant Scheme , International Islamic University Malaysia
ANAESTHESIOLOGY 2010/2011 2014/2015 2015/2016 2016/2017 2017/2018 2018/2019 2019/2020
BASIC ANAESTHESIA & CRITICAL CARE POSTING 2019/2020
OPHTHALMOLOGY 2014/2015
SUBSPECIALTIES ANAESTHESIOLOGY POSTING 2019/2020
In Progress
2019 - Present Profiling the Static and Dynamic Estimates of Glomerular Filtration Rate Equations Based on Creatinine and Cystatin C in Critically Ill Patients in the Malaysian Setting
2018 - Present A Novel Particle Swarm Optimization with Levy Flight Algorithm for Imputation of Missing Creatinine Value.
2017 - Present The Effect of Holy Quran Recitation on Physiological Stress Response in Mechanically Ventilated Patients: A Randomized Controlled Trial
2016 - Present "The Calorie Optimization Study with Indirect Calorimetry in Critically ill Patients: Development of Feeding Protocol in Intensive Care"
2016 - Present "The Calorie Optimization Study with Indirect Calorimetry in Critically ill Patients: Development of Feeding Protocol in Intensive Care"
2015 - Present Development of A Model-based Algorithm for Blood Glucose Control in Malaysian Intensive Care Unit Patients
2015 - Present Modelling of incretin machanism in glucose-insulin control system
Completed
2016 - 2020 "The Calorie Optimization Study with Indirect Calorimetry in Critically ill Patients: Development of Feeding Protocol in Intensive Care"
2015 - 2018 Development of Glomerular Filtration Rate Monitor Based on Creatinine Kinetic Modelling in Critically Ill Patients
2014 - 2016 The Diagnostic And Predictive Performance Of Plasma Neutrophil-Gelatinase Associated Lipocalin In Critically III Patients With Systematic Inflammatory Syndrome, Sepsis And Acute Kidney Injury.
2011 - 2013 RU 2011 -Diagnostic value of procalcitonin, C-reactive protient, Interleukin-8 in critically ill patients admitted with suspected sepsis.
2011 - -1 RU 2011 -Diagnostic value of procalcitonin, C-reactive protient, Interleukin-8 in critically ill patients admitted with suspected sepsis.
2010 - 2011 Handbook on Acute Pain Management Service
2009 - -1 Survey on Routine Intraoperative Temperature Management Practices in Operation Theatre of the Hospital Tengku Ampuan Afzan, Kuantan and Hospital Sultanah Zahirah, Kuala Terengganu
2009 - 2011 Manual for Cardiopulmonary Resuscitation
2009 - 2010 A Randomized Double-Blind Placebo- Controlled, Phase -2b Study to Assess the Safety and Efficacy of ART-123 on Subjects with Sepsis and Disseminated Intravascular Coagulation, a phase 2b Study
2009 - -1 A Randomized Double-Blind Placebo- Controlled, Phase -2b Study to Assess the Safety and Efficacy of ART-123 on Subjects with Sepsis and Disseminated Intravascular Coagulation, a phase 2b Study
2009 - -1 Randomized Control trial Study of the I-Gel and ProSeal Laryngeal Mask Airway in Unparalysed Anaesthetized Patients
2009 - 2012 Anaesthesiology for Medical Undergraduates (2nd Edition)
2008 - 2012 Procalcitonin (PCT) as a Highly Sensitive and Specific Sepsis Marker in the Adult Intensive Care Unit (ICU)
18 August 2017 Best Oral Presentation. Annual Scientific Meeting on the Intensive Care (ASMIC) - National level.
10 August 2017 Best Poster Award (Clincial Medicine Category). Medical Research Symposium 2017 - National level.
10 August 2017 First Runner-up Best For Oral Presentation Award (Clinical Medicine Category). Medical Research Symposium 2017 - National level.
30 April 2017 Best Poster Award (Second Prize) 2017. Malaysian Society of Anaesthesiologist - National level.
30 April 2017 Best Poster Presentation (Second Prize). Malaysian Society of Anaesthesiology - National level.
30 April 2017 Malaysian Society of Anaesthesiology Award 2017. Malaysian Society of Anaesthesiology - National level.
01 January 2017 Contribution for IIUM MyRA 5 star rating. IIUM - University level.
27 August 2016 Malaysian Society of Anaesthesiologist 2016 Award. Malaysian Society of Anaesthesiologist - National level.
11 October 2015 Best Paper Science (Third Prize). Malaysian Technical Universities Conference on Engineering and Technology (MUCET 2015) - National level.
30 September 2015 Department Best Indexed Journal Articles. IIUM Research Invention and Innovation Exhibition 2015 - University level.
13 June 2015 Malaysian Society of Anaesthesiology Award 2015 for Best Oral Presentation. Malaysian Society of Anaesthesiology - National level.
23 September 2013 Best Oral Presentation. Malaysian Society of Intensive Care Medicine - National level.
31 August 2011 Finalist in the Three Minute Thesis Competition. University of Otago - University level.
01 August 2011 The Best Contestant with Primary Supervision from Christchurch Campus in the Christchurch Three Minute Thesis Competition Heat. University of Otago Christchurch - University level.
01 October 2010 Promising Researcher Award. - University level.
09 March 2010 Quality Award. IIUM Promising Researcher Award - University level.
29 June 2006 MMed Anaesthesiology USM Award 2006. Universiti Sains Malaysia - University level.
30 April 2004 Research Fellowship Award. The Heart Foundation of Malaysia - National level.
01 July 1993 Katharine MacDonald Prize for Medical Microbiology. University of St Andrews, Scotland - University level.
Article
2020 Patient asynchrony modelling during controlled mechanical ventilation therapy. Computer Methods and Programs in Biomedicine , 183 (January 2020)
2019 Assessing SB effort via a non-invasive model-based method in mechanically ventilated patients in Malaysian ICU hospital. Indonesian Journal of Electrical Engineering and Computer Science , 15 (3) pp.1232-1240
2019 Study on the blood glucose management with controlled goal feed in Malaysian critically ill patients. IOP Conference Series: Materials Science and Engineering , 469 (2019) pp.1-10
2019 Derivation of a new bioscore for predicting mortality in sepsis. International Medical Journal Malaysia , 18 (1) pp.81-88
2019 Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit. Malaysian Journal of Nutrition , 25 (3) pp.413-421
2019 Model-based glycemic control in a Malaysian intensive care unit: performance and safety study. Medical Devices: Evidence and Research , 2019 pp.215-226
2019 Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia. Indonesian Journal of Electrical Engineering and Computer Science , 15 (1) pp.133-141
2019 Probabilistic glycemic control decision support in icu: proof of concept using Bayesian network. Jurnal Teknologi (Sciences and Engineering) , 81 (2) pp.61-69
2019 Model-based glyceic control in a Malaysian intensive care unit: performance and safety study. Medical Devices: Evidence and Research , 2019 (12) pp.215-226
2018 Assessing mechanical ventilation asynchrony through iterative airway pressure reconstruction. Computer Methods and Programs in Biomedicine , 157 pp.217-224
2018 Sepsis mortality score for the prediction of mortality in septic patients. Journal of Critical Care , 43 pp.163-168
2018 Performance of stochastic targeted blood glucose control protocol by virtual trials in the Malaysian intensive care unit. Computer Methods and Programs in Biomedicine , 162 pp.149-155
2018 Refeeding hypophosphataemia after enteral nutrition in a Malaysian intensive care unit: risk factors and outcome. Asia Pacific Journal of Clinical Nutrition , 27 (2) pp.329-335
2018 Levels and diagnostic value of model-based insulin sensitivity in sepsis: a preliminary study. Indian Journal of Critical Care Medicine , 22 (6) pp.402-407
2018 Acute kidney injury in Malaysian intensive care setting: incidences, risk factors and outcome. Indian Journal of Critical Care Medicine , 22 (12) pp.831-835
2018 Clinical application of respiratory elastance (CARE trial) for mechanically ventilated respiratory failure patients: a model-based study. IFAC-PapersOnLine , 51 (27) pp.209-214
2018 A machine learning model for real-time asynchronous breathing monitoring. IFAC-PapersOnLine , 51 (27) pp.378-383
2018 Virtual trial of glycaemic control performance and nursing workload assessment in diabetic critically ill patients. International Journal of Engineering and Technology(UAE) , 7 (4) pp.54-58
2017 Estimation of plasma insulin and endogenous insulin secretion in critically ill patients using intensive control insulin-nutrition-glucose model. Advanced Science Letters , 23 (6) pp.5510-5514
2017 Performance of glycemic control protocol and virtual trial. Advanced Science Letters , 23 (6) pp.5415-5418
2017 Plasma neutrophil gelatinase associated lipocalin diagnosed acute kidney injury in patients with systemic inflammatory disease and sepsis. Nephrology , 22 (5) pp.412-419
2017 Validating a lower urine output criteria in predicting death in critically ill patients. The International Medical Journal of Malaysia , 16 (1) pp.45-52
2017 Estimates of glomerular filtration rate in the critically ill with sepsis. Kidney International Reports , 2 (4) pp.S33-S34
2017 Prevalence of acute kidney injury and sepsis in a Malaysian intensive care setting. Kidney International Reports , 2 (4) pp.S6-S6
2017 Dynamic changes of plasma neutrophil gelatinase-associated lipocalin predicted mortality in critically ill patients with systemic inflammatory response syndrome. Indian Journal of Critical Care Medicine , 21 (1) pp.23-29
2016 Feasibility of an intensive control insulin-nutrition glucose model ‘icing’ with Malaysian critically-ill patient. International Journal of Pharmacy and Pharmaceutical Sciences , 8 (Supplement 2) pp.40-42
2016 Procalcitonin and Interleukin-6 for predicting culture negative and culture positive bacterial sepsis in critically ill patients with systemic inflammatory response syndrome. International Medical Journal Malaysia , 15 (Supplement issue) pp.85
2016 High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series. Indian Journal of Critical Care Medicine , 20 (6) pp.342-348
2016 Mathematical modeling of glucose-insulin system behavior in Hospital Tengku Ampuan Afzan intensive care unit patients. ARPN Journal of Engineering and Applied Sciences , 11 (18) pp.10899 -10903
2016 The diagnostic ability of procalcitonin and interleukin-6 to differentiate infectious from noninfectious systemic inflammatory response syndrome and to predict mortality. Journal of Critical Care , 33 pp.245-251
2016 The impact of fluid balances in the first 48 hours on mortality in the critically ill patients. International Medical Journal Malaysia , 15 (1) pp.13-18
2015 Refeeding hypophosphataemia in a Malaysian intensive care unit: incidence, risk factors and outcomes. Brunei International Medical Journal , 11 (2) pp.65-73
2015 Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome. Journal of Critical Care , 30 (3) pp.636-642
2014 The clinical utility window for acute kidney injury biomarkers in the critically ill. Critical Care , 18 (601) pp.1-12
2014 Procalcitonin clearance for early prediction of survival in critically ill patients with severe sepsis. Critical Care Research and Practice , 2014 (819034) pp.1-7
2013 High-dose intravenous epoetin does not increase blood pressure in critically ill patients with acute kidney injury. Clinical Nephrology , 79 (5) pp.370-379
2013 Procalcitonin as a sepsis marker: experience of an intensive care setting in Malaysia. Brunei International Medical Journal , 9 (4) pp.243-252
2013 The urine output definition of acute kidney injury is too liberal. Critical Cara , 79 (5) pp.370-379
2013 Combining creatinine and volume kinetics identifies missed cases of acute kidney injury following cardiac arrest. Critical Cara , 17 (1) pp.R7 (1)-R7 (18)
2012 Transient Acute Kidney Injury (AKI) is common following significant kidney hypoperfusion. Nephrology , 17 (Supp.2) pp.54
2012 Hypophosphatemia in the Intensive Care Unit: Incidence, Predictors and Management. The International Medical Journal Malaysia , 11 (1) pp.31-36
2011 New considerations in the design of clinical trials of acute kidney injury. Clinical Investigation , 1 (5) pp.637-650
2011 Acute high-dose intravenous epoetin did not increase blood pressure in critically ill patients with acute kidney injury. Journal of the American Society of Nephrology , 22 pp.296A-297A
2010 High frequency oscillating ventilation (HFOV) in severe acute respiratory distress syndrome (ARDS): a case report . The Internal Medical Journal , 9 (1) pp.51-54
2009 Smoker desaturation during general anaesthesia: a case report. International Medical Journal Malaysia , 8 (1) pp.61-63
2009 Central pontine melinosis resulting in quadriplegia in alcohol withdrawal . ASEAN Journal of Anaesthesiology , 10 (Spec) pp.150
2009 Central pontine myelinosis resulting in quadriplegis in alcohol withdrawal . ASEAN Journal of Anaesthesiology , 10 pp.150
2009 A case series of the use of High Frequency Oscillating Ventilation (HFOV) in Acute Respiratory Distress Syndrome (ARDS) in Adult ICU of the Hospital Tengku Ampuan Afzan, Kuantan . ASEAN Journal of Anaesthesiology , 10 (supp 1) pp.47
2009 Continuous spinal anesthesia for lower limb surgery in patient with poor left ventricular function. ASEAN Journal of Anaesthesiology , 10 (Suppl ) pp.167
2007 Oral Analgesia 24 hours after major operation: A Comparative Study Of Oral Calecoxib and Tramadol in Patients Undergoing Major Gynaecological Operation. ASEAN Jounal of Anaesthesiology , 8 (1) pp.59-65
2007 A comparative study of dexmedetomidine and propofol for sedation in the cardiothoracic intensive care unit. International Medical Journal Malaysia , 6 (2) pp.1-17
2007 Oral analgesic 24 hours after major operation: a comparative study of oral celecoxib and tramadol in patients undergoing major gynaecological operation . Asean Journal of Anaesthesiology , 8 pp.57-63

Conference or Workshop Item
2020 Bone-graft interface in New Zealand White rabbit’s model: A novel Malaysian-made biomaterial, “osteopaste”. In: Malaysia Terchnology Expo 2020
2019 Insulin sensitivity and blood glucose level of sepsis patients in the intensive care unit. In: 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018
2019 Assessment of Malaysian ICU staff perceptions towards STAR glycaemic control protocol. In: 2018 IEEE Region 10 Conference (TENCON 2018)
2018 Investigation of glucose-insulin model efficacy for diabetes patient in the ICU. In: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences, ICIBEL 2017
2018 Blood glucose and sepsis score on sepsis patients requiring insulin therapy. In: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences, ICIBEL 2017
2018 Model iterative airway pressure reconstruction during mechanical ventilation asynchrony: shapes and sizes of reconstruction. In: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences (ICIBEL 2017) in conjunction with APCMBE 2017
2018 Decision support for parenteral nutrition supplementation in ICU using model-based glycemic control protocol. In: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences, ICIBEL 2017
2018 Model-based insulin-nutrition administration for glycemic control in Malaysian critical care: First pilot trial. In: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences, ICIBEL 2017
2017 Comparison between different equations for estimating glomerular filtration rate (GFR) with kinetic estimates of GFR in the critically ill. In: Malaysian Society of Anaesthesiology Annual Scientific Meeting 2017
2017 Prevalence of augmented renal clearance in a Malaysian intensive care setting. In: Malaysian Society of Anaesthesiology Annual Scientific Meeting 2017
2017 Derivation of a multi-biomarker model and score as a predictor of 30-day mortality in critically ill sepsis patients: A prospective cohort study. In: Malaysian Society Anaesthesiology Annual Scientific Meeting 2017
2017 Model-based insulin sensitivity for early diagnosis of sepsis in critical care. In: Annual Scientific Meeting on Intensive Care (ASMIC 2017) : 1st Asian Pediatric Mechanical Ventilation Forum
2017 Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients. In: 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)
2017 Augmented renal clearance in critically ill patients with sepsis: prevalence, risk factors and outcome. In: Medical Research Symposium 2017
2017 Estimates of glomerular filtration rate by the chronic kidney disease epidemiology collaboration equations best correlates with kinetic estimates of glomerular filtration rates in the critically ill. In: Medical Research Symposium 2017
2017 Plasma cystatin C and estimates of glomerular filtration rate using cystatin C independently diagnosed acute kidney injury in critically ill patients with sepsis. In: Medical Research Symposium 2017
2016 Serial measurement of plasma neutrophil gelatinase associated lipocalin in mortality prediction in critically ill patients with systemic inflammatory disease and sepsis. In: Annual Scientific Congress 2016 of the Malaysian Society of Anaesthesiologists & Obstetric Anaesthesia Satellite Meeting
2016 Refeeding syndrome in a Malaysian intensive care unit: an assessment of incidence, risk factors and outcome. In: Annual Scientific Congress 2016 of the Malaysian Society of Anaesthesiologists and the 13th Obstetric Society of Anaesthesiologists Symposium
2016 Performance of blood glucose management protocols in HTAA intensive care unit. In: 2016 IEEE International Conference on Automatic Control and Intelligent Systems (I2CACIS),
2016 Implementation of a prototype glomerular filtration rate application to monitor creatinine kinetic dynamics in critically ill patients. In: 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)
2016 Feasibility of an intensive control insulin-nutrition glucose model ‘icing’ with Malaysian critically-ill patient. In: 2016 Asia Pacific Chemical, Biological & Environmental Engineering Society Copenhagen Conferences (APCBEES)
2016 Performance of STAR virtual trials for diabetic and non-diabetic in HTAA Intensive Care Unit. In: 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)
2016 Estimation of plasma insulin and endogenous insulin secretion in critically ill patients using ICING model. In: International Conference on Computer, Communication, and Control Technology (I4CT 2014)
2015 Plasma neutrophil gelatinase-associated lipocalin best diagnosed acute kidney injury in patients with systemic inflammatory response syndrome and sepsis . In: Malaysian Society of Anaesthesiologists & College of Anaesthesiologists Annual Scientific Congress 2015 & 13th Asian Society of Paediatric Anaesthesiologists Congress
2015 Urine output in diagnosing acute kidney injury and predicting mortality. In: Malaysian Society of Anaesthesiologists & College of Anaesthesiologists Annual Scientific Congress 2015 & 13th Asian Society of Paediatric Anaesthesiologists Congress
2015 Acute kidney injury in a Malaysian Intensive Care Unit: incidence, risk factors and outcome. In: 3rd Singapore-ANZICS Intensive Care Forum 2015 (SG-ANZIC)
2014 Acute kidney injury (AKI) in the intensive care unit (ICU) of Hospital Tengku Ampuan Afzan Kuantan (HTAA): Incidence, risk factors and outcome. In: 8th National Conference for Clinical Research 2014
2013 Early procalcitonin dynamics in critically ill patients with sepsis in a tertiary ICU. In: 11th Congress of the World Federation of Societies of Intensive and Critical Care Medicine
2013 The impact of fluid overload on mortality and acute kidney injury. In: World Congress of Nephrology
2013 Urine output criteria in prediction of mortality or dialysis requirements in the critically ill. In: World Congress of Nephrology 2013
2013 Earlier measurement of biomarkers does not enhance detection of acute kidney injury following significant kidney hypoperfusion. In: World Congress of Nephrology 2013
2012 Early plasma increase in creatinine following significant kidney hypoperfusion. In: Translational Nephrology: From Mechanisms to Therapeutics, Meeting of the Renal Scientists, Australia and New Zealand Society of Nephrology, in conjunction with The Kidney in Health and Disease Research Theme, University of Chicago
2011 A study on incidence, predictors and management of hypophosphaemia in a Malaysian ICU. In: Annual Scientific Meeting on Intensive Care
2011 The utility of biomarker excretion rates in acute kidney injury. In: World Congress of Nephrology 2011
2010 Survey on knowledge and practice of intraoperative temperature management. In: 13th Asian Australasian Congress of Anaesthesiologists
2010 Randomized, control trial study of the i-GelTM and ProSeal LMA in anesthetized, non paralyzed patients. In: 13th Asian Australasian Congress of Anaesthesiologists
2010 Do clinical experience affects competency evaluation using Human Patient Simulator (HPS)? . In: 13th Asian Australasian Congress of Anaesthesiologists
2009 Smoker desaturation during general anaesthesia: a case report. In: 16th Asean Congress of Anaesthesiologist & 7th National Conference on Intensive Care
2007 The use of high-fidelity patient simulation in training healthcare professionals: a proposal for co-operation between the university and Ministry of Health, Malaysia. In: Malaysian Society of Anaesthesiologists & College of Anaesthesiologists Annual Scientific Meeting 2007
2005 A comparative study of dexmedetomidine and propofol for sedation in the cardiothoracic intensive care unit. In: 3rd National Conference on Intensive Care
2004 Descriptive study on the usage of patient-controlled analgesia morphine in post open heart surgery patients in Hospital Universiti Sains Malaysia. In: 12th Congress of Asia Pacific Association of Respiratory Care
2004 APACHE II severity scoring system: evaluating its role in intensive care unit of the Universiti Sains Malaysia Hospital. In: 12th Congress of Asia Pacific Association of Respiratory Care (APARC 2004)

Book
2017 Paraoxonase-1 activities and procalcitonin levels in sepsis and non-infectious systemic inflammatory response syndrome patients in a tertiary intensive care unit. IIUM Press, International Islamic University Malaysia . ISBN 978-967-418-735-4
2012 A cardiopulmonary resuscitation guide for healthcare providers. Department of Anaesthesiology and Intensive Care . ISBN 978-983-44569-0-0
2012 Essential anesthesiology for healthcare professionals. Department of Anaesthesiology and Intensive Care . ISBN 983-44569-0-0

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