Staff Directory


Alfi Khatib

Academic Qualification

  • Ph.D in Pharmacognosy - Doctor of Philosophy, Leiden University, Netherland
  • Master in Pharmacognosy - Masters Degree, Leiden University
  • Bachelor in Agricultural Technology - Bachelor Degree, Bogor Agricultural University

Alfi Khatib (Prof. Dr.)

Professor
IIUM Kuantan Campus

KULLIYYAH OF PHARMACY


alfikhatib@iium.edu.my
4940


Expert Profile


Alfi Khatib obtained his BSc degree from Bogor Agricultural University, Indonesia. The Dutch government awarded the TALIS scholarship for his Master and PhD programmes in Pharmacognosy at Leiden University, the Netherlands. Upon completing his PhD in 2006, he joined Metabolomics Section at Leiden University as a postdoctoral researcher until August 2008. He moved to Universiti Putra Malaysia as a senior lecturer in September 2008 before joining the Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, in March 2013. He won the Dutch New Venture Competition Round 2 in 2006 based on his PhD work on iso-alpha-acids purification. IIUM awarded him the Excellent Research Achievement Award for several consecutive years from 2017 to 2023. He has secured several research grants from the Malaysian government for his research on the standardization of natural products using metabolomics approach and purification of bioactive compounds from Malaysian plants. He has published more than 150 articles in peer-reviewed international journals (h-index > 35 ) and international patent.


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Pharmacy ~ Pharmacognosy


Professional Membership


  • 2012 - 2020: Member of Profesional Body / Association: (Member), American Chemical Society
  • 2014 - 2015: Member of Profesional Body / Association: (Member), Malaysia Agricultural economics Association
  • 2016 - 2021: Member of Profesional Body / Association: (Member), The Malaysian Natural Products Society
  • 2022: Member of Profesional Body / Association: (Member), Majlis Profesor Negara


Research Projects


Completed
2022 - 2023 Botanical Identification and Evaluation of Metabolite Profile of Labi-labi Leaves using Gas Chromatography-mass Spectrometry, Liquid Chromatography-mass Spectrometry, and Fourier Transformed-infra Red Spectroscopy
2022 - 2022 LC-MS Analysis of "Buah Pinang"
2022 - 2022 Lypoxigenase Inhibitory Activity of "Buah Pinang"
2021 - 2021 GCMS and LCMS-Q-TOF Analysis
2020 - 2022 BIOACTIVE COMPOUNDS IN TETRACERA SCANDENS EXTRACTS BY LC-QTOF-MS-BASED METABOLOMICS AND CORRELATION WITH XANTHINE OXIDASE ACTIVITY
2020 - 2023 IDENTIFICATION AND ISOLATION OF ?-GLUCOSIDASE INHIBITORS FROM THE OPTIMISED LEAVES EXTRACT OF COSMOS CAUDATUS
2020 - 2021 Multiplatform based metabolomics analysis of Alga
2020 - 2020 GC-MS Analysis of Kaempferia Galangal Extracts
2020 - 2021 Elucidation on the Antimicrobial Property of Rosadiflora Species towards Human Pathogen
2020 - 2021 Preprocessing of LCMS data of human serum in Medan
2020 - 2023 Molecular characterization and modification of 5,7,8-trihydroxyflavone and its chemical analogues to discover a novel antihyperglycemic agent
2019 - 2019 GC-MS Analysis of Kecombrong
2019 - 2022 Identification of alpha-glucosidase inhibitors from Psychotria malayana Jack leaf using multi-platform metabolomics approach and protein-ligand interaction with molecular docking in treating diabetes mellitus
2018 - 2021 Identification of ?-Glucosidase Inhibitors from Psychotria malayana Leaf Extract using Liquid Chromatography-Mass Spectrometry-Based Metabolomics and Protein-Ligand Interaction with Molecular Docking
2016 - 2019 Understanding Anti-Angiogenesis Mechanism of Porcupine Bezoar Bioactive Compounds on Colon and Pancreas Cancer Cells Using Xenograft Zebrafish Model MyGrants : Understanding Anti-metastatic Mechanisms of Porcupine Bezoar Extract on Colon and Pancreas Cancer Cells Using in vitro Model
2016 - 2018 Understanding of anti-cancer properties of Neolamarckia cadamba leaves on breast cancer: Prospective therapeutic Neolamarckia cadamba extracts
2016 - 2016 2D NMR (JRES, COSY, HMBC) OF ORTHOSIPHON STAMINEUS AND JAPANESE RICE BRANS
2016 - 2017 1H NMR MEASUREMENT OF COLEUS AMBONICUS
2016 - 2018 Investigation of bioactive compounds from Luvunga scandens and its cytotoxicity against breast cancer cell
2016 - 2017 Multivariate Calibration of Antioxidant Activity of Momordica charantia Fruit and its Fourier Transform Infrared Spectroscopy Based Fingerprinting
2016 - 2020 Isolation, Identification and Computational Studies of a-Glucosidase Inhibitors from Clinacanthus nutans (Burm F.) Lindau Leaves Extracts
2015 - 2020 Evaluation of External Application of Halal Topical Cream of Neolamarckia Cadamba Leaves on Breast Cancer Cells in Rats Leading Towards Clinical Trial on Human Breast Cancer
2015 - 2014 Alfa-amylase inhibitor from Orthosiphonstamineus & Metabolomics Profile of Indonesian and Japanese Rice Brans
2014 - 2016 Chemical Profilinf of Mommordica Charantia Possessing Alpha-Glucosidase Inhibitory Activity using GC-MS based Metabolomics
2014 - 2017 Effect of Standardized Extract of Clinacanthus Nutans in Hiperuricemia Induced Mice
2014 - 2017 Fingerprinting Of Sygygium Companulatum (Kelat Paya) Leaf Extracts Utilizing Gas Chromatography-Mass Spectrometery (GC-MS) And Metabolomics For Their Quality And Efficacy Profile.
2013 - 2016 Comprehensive Evaluation of Anti-Diabetic Activity of Momordica Charantia Fruits On Streptozocin Induced Diabetic Rats Using NMR Metabolomics Approach
2013 - 2020 Production of Chemical Markers From Labisia Pumila (Labisiaquinones B and Two Alkylresorcinols and Clinacanthus Nutans) Clinacosides A,B,C and Cycloclinacoside A2
On-Going
2022 - Present Characterization on the Properties of Mitragyna Speciosa, Deletion of Toxicity Genes, Development of Kratom-Based Medicinal Products and It's Legal Implication
2021 - Present Profiling of metabolomes and proteomes as biomarkers for Post COVID-19 Syndrome.
2019 - Present A Pharmacophore-based Virtual Screening Approach for Identifying Bioactive Compounds from Various Malaysian Plants As Potential Protein Arginine Deiminase IV (PAD4) Inhibitors.
2017 - Present Investigation the Effect of Scented Flower Enfleurage Using Different Lipophilic Carriers on Yield and Phytochemical Constituents of the Produced Essential Oils
2016 - Present The Danio rerio angiogenesis inhibitor as anti-cancer effects in Clinacanthus nutans, Orthosipon stamineus Luvunga scandes and Annona muricate extracts
- Microbial Biotransformation of Terpenoids for the discovery of anticancer agents
- Microbial Biotransformation of Terpenoids for the discovery of anticancer agents


Award & Recognition


02 Aug, 2023 High Impact Responsible Research Award during Takrim 2023 - International Islamic University Malaysia University
02 Aug, 2023 Highest Citation in Indexed Journal Award during Takrim 2023 - International Islamic University Malaysia University
02 Aug, 2023 Top 10 Contributors to IIUM's Research Performance during Takrim 2023 - International Islamic University Malaysia University
15 May, 2023 Highest citation in indexed journal award (medical and health sciences)-1st place-awarded during the Responsible Research and Innovation Appreciation Day 2023 - International Islamic University Malaysia University
15 May, 2023 Top 30 Contributors to IIUM's Research Performance- the Responsible Research and Innovation Appreciation Day 2023 - Others University
15 May, 2023 High Impact Responsible Research Award (Medical and Health Science) 1st Place-the Responsible Research and Innovation Appreciation Day 2023 - Others University
27 Jul, 2022 Top 10 Contributors to IIUM's Research Performance - Others University
27 Jul, 2022 High Impact Responsible Research Award-Medical and Health Science - IIUM Takrim Award 2022 University
27 Jul, 2022 Highest Citation in Indexed Journal Award-Medical and Health Sciences - Others University
30 May, 2022 High Impact Responsible Research Award (Medical and Health Science Category) - International Islamic University Malaysia University
30 May, 2022 Highest Citation in Indexed Journal Award (in Medical and Health Science) - Others University
30 May, 2022 Highest citation in Indexed journal award (best citation overall) - International Islamic University Malaysia University
30 May, 2022 Top 50 Contributors to IIUM's Research Performance - International Islamic University Malaysia University
22 Feb, 2022 Top 3 Academic Staff with Highest Number of Research Articles (Co-Author) - Kulliyyah of Pharmacy Takrim Day 2021 KCDIO
22 Feb, 2022 Top 3 Academic Staff with Highest Number of Research Articles-First IIUM Author/Corresponding Author) - Kulliyyah of Pharmacy Takrim Day 2021 KCDIO
10 Dec, 2021 Top Researchers with the highest number of joint publications from 2019-2021 - International Islamic University Malaysia University
21 Oct, 2021 The Most Creative & Innovative Lecturer - Kulliyyah of Pharmacy, IIUM KCDIO
27 Jul, 2021 Highest Citation in Indexed Journal-Medical and Health Science - TAKRIM 2021- International Islamic University Malaysia University
27 Jul, 2021 Top Ten Contributor to IIUM's Research Performance - TAKRIM 2021- International Islamic University Malaysia University
19 Aug, 2020 Top 3 academic staff with highest H index - Kulliyyah of pharmacy IIUM KCDIO
19 Aug, 2020 Top 3 academics staff with highest number of research articles - Kulliyyah of Pharmacy IIUM KCDIO
24 Jul, 2019 Highest Number of Publications Award (Indexed Journal Articles) Medical and Health Sciences-IIUM Takrim Day 2019 - International Islamic University Malaysia University
24 Jul, 2019 Top 30 Contributors to IIUM's Research Performance Award-IIUM Takrim Day 2019 - International Islamic University Malaysia University
19 Mar, 2019 Reviewing award March 2019: Journal of Herbal Medicine - Elsevier International
18 Feb, 2019 Reviewing Award: BBA - Molecular Basis of Disease - BBA - Molecular Basis of Disease-Elsevier International
18 Jan, 2019 Heliyon Reviewing Award - Elsevier-Heliyon International
07 Jan, 2019 Reviewing Award Jan 2019: Food Chemistry-Elsevier - Food Chemistry-Elsevier International
01 Oct, 2018 Outsatnding contribution in Reviewing - Phytomedicine-Elsevier International
12 Jul, 2018 Best Journa Article Award (Medical and Helath Sciences) - International Islamic University Malaysia University
12 Jul, 2018 Highest Number of Publication Award Indexed Journal Articles (Medical and Helth Sciences) - International Islamic University Malaysia University
01 Nov, 2017 Rcognized reviewing - Journal of Taibah University Medical Sciences-Elsevier International
01 Sep, 2017 Recognized Reviewing - Journal of Chromatography B- Elsevier International
27 Apr, 2017 Highest number of publication in citation-indexed journals award - International Islamic University Malaysia University
27 Apr, 2017 The most productive researcher award (Health and Medical) - International Islamic University Malaysia University
02 Sep, 2016 Outstanding Contributor Journal Articles Indexed in Scopus and WOS - International Islamic University Malaysia University
29 Sep, 2015 Department Bset Non-Indexed Journal Articles - IIUM University
08 Nov, 2012 Gold medal - Research, Invention, Innovation and Design 2012 National
19 Jul, 2012 Gold Medal - Pameran Reka Cipta, Penyelidikan dan Inovasi Malaysia 2012 National
26 Jun, 2012 Perkhidmatan Cemerlang 2011 - Universiti Putra Malaysia University
28 Jun, 2011 Anugerah Perkhidmatan Cemerlang 2010 - Universiti Putra Malaysia University
15 Jul, 2010 Anugerah Perkhidmatan Cemerlang 2009 - Universiti Putra Malaysia University