Staff Directory


Alfi Khatib

Academic Qualification

  • Ph.D in Pharmacognosy - Doctor of Philosophy, Leiden University, Netherland
  • Master in Pharmacognosy - Masters Degree, Leiden University
  • Bachelor in Agricultural Technology - Bachelor Degree, Bogor Agricultural University

Alfi Khatib (Assoc. Prof. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF PHARMACY

Other's position:

Head, Kulliyyah of Pharmacy


alfikhatib@iium.edu.my
4940


Expert Profile


After Alfi Khatib obtained his Bsc degree from Bogor Agricultural University, Indonesia, he was awarded the TALIS scholarship by the Dutch government for his Master and Ph.D programmes in Pharmacognosy in Leiden University, the Netherlands. Upon completion of his Ph.D in 2006, he joined Metabolomics Section in Leiden University as a postdoctoral researcher until August 2008. He moved to Universiti Putra Malaysia as a senior lecturer in September 2008 before joining the Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia as an Associate Professor in April 2013.
He was the winner of the Dutch New Venture Competition Round 2 in 2006 based on his Ph.D work on iso-alpha-acids purification. He was awarded the Excellent Achievement Award by University Putra Malaysia for three consecutive years 2009, 2010 and 2011. He won a gold medal for his invention on FTIR-ATR Spectroscopy based metabolite fingerprinting as a direct determination of butter adulerated with lard at Pameran Reka Cipta, Penyelidikan dan Inovasi Malaysia UPM in 2012. Another gold medal was awarded to him based on his invention Analysis of Butter Adulterated with Lard by 1H-NMR for Halal Verification  during Research Invention, Innovation and Design UiTM in 2012.
His research interest is in natural product chemistry. He has received several research grants from the Malaysian government for his research on the standardization of natural products using metabolomics approach and purification of bioactive compounds from Malaysian plants. He has published more than 90 articles in peer reviewed international journals and one international patent.


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Pharmacy ~ Pharmacognosy


Professional Membership


  • 2012 - 2020: Member of Profesional Body / Association: (Member), American Chemical Society
  • 2014 - 2015: Member of Profesional Body / Association: (Member), Malaysia Agricultural economics Association
  • 2016 - 2021: Member of Profesional Body / Association: (Member), The Malaysian Natural Products Society


Teaching Responsibilities


ADVANCE ANALYTICAL METHODS FOR HALAL HARAM PRODUCTS 2019/2020
BASIC PHARMACEUTICAL ANALYSIS 2020/2021 2019/2020
FUNDAMENTALS OF MEDICINAL CHEMISTRY 2013/2014
INTRODUCTION TO BIOMEDICAL LABORATORY SCIENCES 2013/2014 2015/2016 2014/2015
PHARMACEUTICAL ANALYSIS I 2013/2014 2016/2017 2014/2015 2015/2016 2017/2018 2012/2013 2018/2019
PHARMACEUTICAL ANALYSIS II 2017/2018 2013/2014 2015/2016 2016/2017 2018/2019 2019/2020 2014/2015
PHARMACEUTICAL INSTRUMENTAL ANALYSIS 2020/2021
PHARMACOGNOSY 2018/2019 2019/2020 2017/2018 2016/2017 2012/2013 2013/2014 2014/2015 2020/2021 2015/2016
RESEARCH PROJECT 1 2020/2021 2019/2020 2017/2018
RESEARCH PROJECT-LITERATURE SEARCH 2015/2016


Research Projects


Completed
2020 - 2020 GC-MS Analysis of Kaempferia Galangal Extracts
2019 - 2019 GC-MS Analysis of Kecombrong
2018 - 2021 Identification of ?-Glucosidase Inhibitors from Psychotria malayana Leaf Extract using Liquid Chromatography-Mass Spectrometry-Based Metabolomics and Protein-Ligand Interaction with Molecular Docking
2016 - 2019 Understanding Anti-Angiogenesis Mechanism of Porcupine Bezoar Bioactive Compounds on Colon and Pancreas Cancer Cells Using Xenograft Zebrafish Model MyGrants : Understanding Anti-metastatic Mechanisms of Porcupine Bezoar Extract on Colon and Pancreas Cancer Cells Using in vitro Model
2016 - 2018 Understanding of anti-cancer properties of Neolamarckia cadamba leaves on breast cancer: Prospective therapeutic Neolamarckia cadamba extracts
2016 - 2017 Multivariate Calibration of Antioxidant Activity of Momordica charantia Fruit and its Fourier Transform Infrared Spectroscopy Based Fingerprinting
2016 - 2016 2D NMR (JRES, COSY, HMBC) OF ORTHOSIPHON STAMINEUS AND JAPANESE RICE BRANS
2016 - 2017 1H NMR MEASUREMENT OF COLEUS AMBONICUS
2016 - 2018 Investigation of bioactive compounds from Luvunga scandens and its cytotoxicity against breast cancer cell
2016 - 2020 Isolation, Identification and Computational Studies of a-Glucosidase Inhibitors from Clinacanthus nutans (Burm F.) Lindau Leaves Extracts
2015 - 2020 Evaluation of External Application of Halal Topical Cream of Neolamarckia Cadamba Leaves on Breast Cancer Cells in Rats Leading Towards Clinical Trial on Human Breast Cancer
2015 - 2014 Alfa-amylase inhibitor from Orthosiphonstamineus & Metabolomics Profile of Indonesian and Japanese Rice Brans
2014 - 2016 Chemical Profilinf of Mommordica Charantia Possessing Alpha-Glucosidase Inhibitory Activity using GC-MS based Metabolomics
2014 - 2017 Effect of Standardized Extract of Clinacanthus Nutans in Hiperuricemia Induced Mice
2014 - 2017 Fingerprinting Of Sygygium Companulatum (Kelat Paya) Leaf Extracts Utilizing Gas Chromatography-Mass Spectrometery (GC-MS) And Metabolomics For Their Quality And Efficacy Profile.
2013 - 2016 Comprehensive Evaluation of Anti-Diabetic Activity of Momordica Charantia Fruits On Streptozocin Induced Diabetic Rats Using NMR Metabolomics Approach
2013 - 2020 Production of Chemical Markers From Labisia Pumila (Labisiaquinones B and Two Alkylresorcinols and Clinacanthus Nutans) Clinacosides A,B,C and Cycloclinacoside A2
On-Going
2021 - Present GCMS and LCMS-Q-TOF Analysis
2020 - Present Preprocessing of LCMS data of human serum in Medan
2020 - Present Multiplatform based metabolomics analysis of Alga
2020 - Present Elucidation on the Antimicrobial Property of Rosadiflora Species towards Human Pathogen
2019 - Present Identification of alpha-glucosidase inhibitors from Psychotria malayana Jack leaf using multi-platform metabolomics approach and protein-ligand interaction with molecular docking in treating diabetes mellitus
2019 - Present A Pharmacophore-based Virtual Screening Approach for Identifying Bioactive Compounds from Various Malaysian Plants As Potential Protein Arginine Deiminase IV (PAD4) Inhibitors.
2017 - Present Investigation the Effect of Scented Flower Enfleurage Using Different Lipophilic Carriers on Yield and Phytochemical Constituents of the Produced Essential Oils
2016 - Present The Danio rerio angiogenesis inhibitor as anti-cancer effects in Clinacanthus nutans, Orthosipon stamineus Luvunga scandes and Annona muricate extracts
- BIOACTIVE COMPOUNDS IN TETRACERA SCANDENS EXTRACTS BY LC-QTOF-MS-BASED METABOLOMICS AND CORRELATION WITH XANTHINE OXIDASE ACTIVITY
- Molecular characterization and modification of 5,7,8-trihydroxyflavone and its chemical analogues to discover a novel antihyperglycemic agent
- IDENTIFICATION AND ISOLATION OF ?-GLUCOSIDASE INHIBITORS FROM THE OPTIMISED LEAVES EXTRACT OF COSMOS CAUDATUS
- Microbial Biotransformation of Terpenoids for the discovery of anticancer agents
- Microbial Biotransformation of Terpenoids for the discovery of anticancer agents


Award & Recognition


19 Aug, 2020 Top 3 academic staff with highest H index - Kulliyyah of pharmacy IIUM KCDIO
19 Aug, 2020 Top 3 academics staff with highest number of research articles - Kulliyyah of Pharmacy IIUM KCDIO
24 Jul, 2019 Highest Number of Publications Award (Indexed Journal Articles) Medical and Health Sciences-IIUM Takrim Day 2019 - International Islamic University Malaysia University
24 Jul, 2019 Top 30 Contributors to IIUM's Research Performance Award-IIUM Takrim Day 2019 - International Islamic University Malaysia University
19 Mar, 2019 Reviewing award March 2019: Journal of Herbal Medicine - Elsevier International
18 Feb, 2019 Reviewing Award: BBA - Molecular Basis of Disease - BBA - Molecular Basis of Disease-Elsevier International
18 Jan, 2019 Heliyon Reviewing Award - Elsevier-Heliyon International
07 Jan, 2019 Reviewing Award Jan 2019: Food Chemistry-Elsevier - Food Chemistry-Elsevier International
01 Oct, 2018 Outsatnding contribution in Reviewing - Phytomedicine-Elsevier International
12 Jul, 2018 Best Journa Article Award (Medical and Helath Sciences) - International Islamic University Malaysia University
12 Jul, 2018 Highest Number of Publication Award Indexed Journal Articles (Medical and Helth Sciences) - International Islamic University Malaysia University
01 Nov, 2017 Rcognized reviewing - Journal of Taibah University Medical Sciences-Elsevier International
01 Sep, 2017 Recognized Reviewing - Journal of Chromatography B- Elsevier International
27 Apr, 2017 Highest number of publication in citation-indexed journals award - International Islamic University Malaysia University
27 Apr, 2017 The most productive researcher award (Health and Medical) - International Islamic University Malaysia University
02 Sep, 2016 Outstanding Contributor Journal Articles Indexed in Scopus and WOS - International Islamic University Malaysia University
29 Sep, 2015 Department Bset Non-Indexed Journal Articles - IIUM University
08 Nov, 2012 Gold medal - Research, Invention, Innovation and Design 2012 National
19 Jul, 2012 Gold Medal - Pameran Reka Cipta, Penyelidikan dan Inovasi Malaysia 2012 National
26 Jun, 2012 Perkhidmatan Cemerlang 2011 - Universiti Putra Malaysia University
28 Jun, 2011 Anugerah Perkhidmatan Cemerlang 2010 - Universiti Putra Malaysia University
15 Jul, 2010 Anugerah Perkhidmatan Cemerlang 2009 - Universiti Putra Malaysia University


Publications


Article

2020 Alpha-glucosidase inhibitory effect of psychotria malayana jack leaf: A rapid analysis using infrared fingerprinting. Molecules, 25 (18) pp. 1-11
2020 Characterization of α-glucosidase inhibitors from psychotria malayana jack leaves extract using LC-MS-based multivariate data analysis and in-silico molecular docking. Molecules, 25 (24) pp.
2020 Determination toxic effects of Hystrix Brachyura Bezoar extracts using cancer cell lines and embryo zebrafish (Danio rerio) models and identification of active principles through GC-MS analysis. Journal of Ethnopharmacology, 262 () pp. 1-13
2020 GC–MS metabolomics revealed protocatechuic acid as a cytotoxic and apoptosis-inducing compound from black rice brans. Food Science and Biotechnology, 29 (6) pp. 825-835
2020 Medicinal potential of isoflavonoids: Polyphenols that may cure diabetes. Molecules, 25 () pp.
2020 NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition. BMC Complementary Medicine and Therapies, 20 (1) pp.
2020 Recent insights into chemical and pharmacological studies of bee bread. Trends in Food Science and Technology, 97 () pp. 300-316
2020 Review: Antimicrobial properties of apis mellifera’s bee venom. Toxins, 12 (7) pp. 1-17
2020 The inhibitory effects of heterotrigona itama honey marinades on the formation of carcinogenic heterocyclic amines in grilled beef satay. Molecules, 25 (17) pp. 1-19
2020 The investigation of antioxidant and antidiabetic activities of Christia vespertilionis leaves extracts. South African Journal of Botany, 133 () pp. 227-235
2020 The toxic impact of honey adulteration: a review. Foods, 9 (11) pp.
2019 A comparative characterization of physicochemical and antioxidants properties of processed Heterotrigona itama honey from different origins and classification by chemometrics analysis. Molecules, 24 (21) pp. 1-20
2019 Alpinia zerumbet (Pers.): Food and medicinal plant with potential in vitro and in vivo anti-cancer activities. Molecules, 24 (13) pp. 1-14
2019 Anticancer activity of grassy Hystrix brachyura bezoar and its mechanisms of action: An in vitro and in vivo based study. Biomedicine & Pharmacotherapy, 114 () pp. 1-13
2019 Antidiabetic and antioxidants activities of Clinacanthus nutans (Burm F.) Lindau leaves extracts. International Food Research Journal, 26 (1) pp. 319-327
2019 Chemometrics analysis combined with GC-MS and NMR spectroscopy analysis of fatty acids as a means of discriminating butterfat adulteration. Journal of Pharmacy and Nutrition Sciences, 9 (2) pp. 87-94
2019 Discrimination of clinacanthus nutans extracts and correlation with antiplasmodial activity using ATR-FTIR fingerprinting. Vibrational Spectroscopy, 104 () pp. 1-6
2019 Evaluation of the α-glucosidase inhibitory and free radical scavenging activities of selected traditional medicine plant species used in treating diabetes. International Food Research Journal, 26 (1) pp. 75-85
2019 Fourier transform infrared spectroscopy and multivariate analysis of milk from different goat breeds. International Journal of Food Properties, 22 (1) pp. 1673-1683
2019 GC-MS analysis of metabolites from soxhlet extraction, ultrasound-assisted extraction and supercritical fluid extraction of Salacca zalacca flesh and its alpha-glucosidase inhibitory activity. Natural Product Research, () pp.
2019 Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking. Journal of Pharmaceutical Analysis, 9 (2) pp. 91-99
2019 Influence of origins and bee species on physicochemical, antioxidant properties and botanical discrimination of stingless bee honey. International Journal of Food Properties, 22 (1) pp. 239-264
2019 Optimization of hyperglycemic induction in zebrafish and evaluation of its blood glucose level and metabolite fingerprint treated with psychotria malayana Jack Leaf extract. Molecules, 24 (8) pp. 1-22
2019 Plants mentioned in the Islamic scriptures (Holy Qur'ân and Ahadith): traditional uses and medicinal importance in contemporary times. Journal of Ethnopharmacology, 243 () pp. 1-8
2019 Plants mentioned in the Islamic Scriptures (HolyQur'ân and Ahadith): traditional uses and medicinal importance in contemporary times. Journal of Ethnopharmacology, 243 () pp. 1-18
2019 Rapid investigation of α-glucosidase inhibitory activity of Clinacanthus nutans leaf using infrared fingerprinting. Vibrational Spectroscopy, 100 () pp. 22-29
2019 The promise of zebrafish as a model of metabolic syndrome. Experimental Animals, 68 (4) pp. 407-416
2019 Toxicity study on Clinacanthus nutans leaf hexane fraction using Danio rerio embryos. Toxicology Reports, 6 () pp. 1148-1154
2019 Variation in the metabolites and α-glucosidase inhibitory activity of Cosmos caudatus at different growth stages. BMC Complementary and Alternative Medicine, 19 (1) pp. 1-15
2019 Variation in the metabolites and αglucosidase inhibitory activity of Cosmos caudatus at different growth stages. BMC Complementary And Alternative Medicine, 19 (1) pp. 1-15
2018 Antioxidant activities of Dialium indum L. fruit and gas chromatography-mass spectrometry (GC-MS) of the active fractions. Antioxidants, 7 (11) pp. 1-14
2018 Antioxidant and α‐glucosidase inhibitory activities and gas chromatography–mass spectrometry pro le of salak (salacca zalacca) fruit peel extracts. Pharmacognosy Research, 10 (4 (Oct.-Dec.)) pp. 385-390
2018 Antiradical and xanthine oxidase inhibitory activity evaluations of Averrhoa bilimbi L. leaves and identification of bioactive constituents through LC-QTOF-MS/MS and molecular docking approach. Antioxidants, 7 (10) pp. 1-16
2018 Characterization of α-glucosidase inhibitors from clinacanthus nutans lindau Llaves by gas chromatography-mass spectrometry-based metabolomics and molecular docking simulation. Molecules, 23 (9) pp. 1-21
2018 Chemical profile, total phenolic content, DPPH free radical scavenging and α-glucosidase inhibitory activities of cosmos caudatus kunth leaves. Pertanika Journal of Tropical Agricultural Science, 41 (3) pp. 1367-1381
2018 Chemical profile, total phenolic content, DPPH free radical scavenging and α-lucosidase inhibitory activities of cosmos caudatus kunth leaves. Pertanika Journal of Tropical Agricultural Science, 41 (3) pp. 1367-1381
2018 Classification of raw stingless bee honeys by bee species origins using the NMR- and LC-MS-based metabolomics approach. Molecules, 23 (9) pp. 1-18
2018 Comparative analysis of chemical composition, antioxidant activity and quantitative characterization of some phenolic compounds in selected herbs and spices in different solvent extraction systems. Molecules, 23 (2) pp. 1-17
2018 Correlation of FT-IR fingerprint and α-glucosidase inhibitory activity of Salak (Salacca zalacca) fruit extracts utilizing orthogonal partial least square. Molecules, 23 (6) pp. 1-10
2018 Effects of different types of soy sauce on the formation of heterocyclic amines in roasted chicken. Food Additives & Contaminants, 35 (5) pp. 870-881
2018 Inhibitory effect of mixture herbs/spices on formation of heterocyclic amines and mutagenic activity of grilled beef. Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 35 (10) pp.
2018 Metabolomic analysis and biochemical changes in the urine and serum of streptozotocin-induced normal- and obese-diabetic rats. Journal of Physiology and Biochemistry, 74 (3) pp. 403-416
2018 Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines. South African Journal of Botany, 116 () pp. 16-24
2018 Saffron (Crocus sativus L.): as an antidepressant. Journal of Pharmacy and Bioallied Sciences, 10 (4) pp. 1-8
2017 α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar. Journal of Food Biochemistry, 41 (2) pp. 1-8
2017 Antioxidant and antidiabetic effects of flavonoids: a structure-activity relationship based study. BioMed Research International, 2017 () pp. 1-14
2017 Application of BATMAN and BAYESIL for quantitative 1H-NMR based metabolomics of urine: discriminant analysis of lean, obese,and obese-diabetic rats. Metabolemics, 13 (11) pp. 1-14
2017 Authentication of butter from lard adulteration using high-resolution of nuclear magnetic resonance spectroscopy and high-performance liquid chromatography. International Journal of Food Properties, 20 (9) pp. 2147-2156
2017 Cancer chemoprevention study of Luffa Aegyptiaca seed extract on human breast cancer cell lines (MCF-7). International Journal of Allied Health Sciences, 1 (1) pp. 13-13
2017 Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting. Analytical Letters, 50 (12) pp. 1977-1991
2017 Characterization of metabolite profile in Phyllanthus niruri and correlation with bioactivity elucidated by nuclear magnetic resonance based metabolomics. Molecules, 22 (6) pp. 1-14
2017 Discrimination of Ipomoea aquatica cultivars and bioactivity correlations using NMR-based metabolomics approach. Plant Biosystems, 151 (5) pp. 833-843
2017 Discriminative analysis of different grades of Gaharu (Aquilaria malaccensis Lamk.) via 1H-NMR-based metabolomics using PLS-DA and random forests classification models. molecules, 22 (10) pp. 1-13
2017 Effect of Ipomoea aquatica ethanolic extract in streptozotocin (STZ) induced diabetic rats via 1H NMR-based metabolomics approach. Phytomedicine, 36 () pp. 201-209
2017 Extraction of α-glucosidase inhibitory compounds from Phaleria macrocarpa fruit flesh using solvent, sonication, and subcritical carbon dioxide soxhlet methods. Journal of Food Biochemistry, 41 (5) pp. 1-11
2017 Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction. Separation Science and Technology, 52 (5) pp. 852-863
2017 In vitro antioxidant and, α-glucosidase inhibitory activities and comprehensive metabolite profiling of methanol extract and its fractions from Clinacanthus nutans. BMC Complementary and Alternative Medicine, 17 (1) pp. 1-10
2017 Low inhibition of alpha-glucosidase and xanthine oxidase activities of ethanol extract of Momordica charantia fruit. Journal of Pharmaceutical Negative Results, 8 (1) pp. 20-24
2017 Morinda citrifolia L. leaf extract prevent weight gain in Sprague-Dawley rats fed a high fat diet. Food & Nutrition Research, 61 () pp. 1-13
2017 Rapid investigation of a-glucosidase inhibitory activity of Phaleria macrocarpa extracts using FTIR-ATR based fingerprinting. Journal of Food and Drug analysis, 25 (2) pp. 306-315
2017 Understanding of anti-cancer properties of neolamarckia cadamba leaves extract on breast cancer cell. International Journal of Allied Health Sciences, 1 (1) pp. 20-20
2017 Urinary metabolic profiling of cisplatin nephrotoxicity andnephroprotective effects of Orthosiphon stamineus leaves elucidatedby1H NMR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis, 135 () pp. 20-30
2017 Urinary metabolomics study on the protective role of Orthosiphon stamineus in Streptozotocin induced diabetes mellitus in rats via 1H NMR spectroscopy. BMC Complementary and Alternative Medicine, 17 (1) pp. 1-13
2016 α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar. Journal of Food Biochemistry, () pp. 1-8
2016 Alpha-glucosidase inhibitor and anti-oxidant compounds from orthosiphon stamineus benth using FTIR based metabolomics. Jurnal Teknologi dan Industri Pangan, 27 (1) pp. 17-30
2016 An investigation into the antiobesity effects of morinda citrifolia l. leaf extract in high fat diet induced obese rats using a 1H NMR metabolomics approach. Journal of Diabetes Research, 2016 () pp. 2391592-1-2391592-15
2016 Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica. Records of Natural Products, 10 (6 (November -December)) pp. 701-707
2016 Chemical profiling of different types of soy sauce and the relationship with its sensory attributes. Journal of Food Quality, 39 (6) pp. 714-725
2016 Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry. Asian Pacific Journal of Tropical Medicine, 9 (4) pp. 402-409
2016 Comparative evaluation of nutritional compositions, antioxidant capacities, and phenolic compounds of red and green sessile joyweed (Alternanthera sessilis). Journal of Functional Foods, 21 () pp. 263-271
2016 Differentiation of fatty acid composition of butter adulterated with lard using gas chromatography mass spectrometry combined with principal componenet analysis. Jurnal Teknologi, 78 (2) pp. 171-177
2016 Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity. International Journal of Food Properties, 19 (12) pp. 2817-2831
2016 Metabolic alteration in obese diabetes rats upon treatment with Centella asiatica extract. Journal of Ethnopharmacology, 180 () pp. 60-69
2016 Metabolic and biochemical changes in streptozotocin induced obese-diabetic rats treated with Phyllanthus niruri extract. Journal of Pharmaceutical and Biomedical Analysis, 128 () pp. 302-312
2016 Metabolite profiling of Neptunia oleracea and correlation with antioxidant and α-glucosidase inhibitory activities using 1H NMR-based metabolomics. Phytocehmistry Letters, 16 () pp. 23-33
2016 Screening of various parts of phaleria macrocarpa plant for α-glucosidase inhibitory activity. Journal of Food Biochemistry, 40 (2) pp. 201-210
2015 Detection of butter adulteration with lard by employing H-1-NMR spectroscopy and multivariate data analysis. Journal of Oleo Science, 64 (7) pp. 607-703
2015 Detection of butter adulteration with lard using differential scanning calorimetry. International Food Research Journal, 22 (2) pp. 832-839
2015 Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves - GCMS based metabolomics approach. Journal of Food and Drug Analysis, 23 () pp. 433-441
2015 Evaluation of antidiabetic properties of Momordica charantia in streptozotocin induced diabetic rats using metabolomics approach. International Food Research Journal, 22 (3) pp. 1299-1307
2015 FTIR-ATR spectroscopy based metabolite fingerprinting as a direct determination of butter adulterated with lard. International Journal of Food Properties, 18 (2) pp. 372-379
2015 Infrared–metabolomics approach in detecting changes in andrographis paniculata metabolites due to different harvesting ages and times. Journal of the Science of Food and Agriculture, 95 (12) pp. 2533-2543
2015 Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics. Scientia Horticulturae, 192 () pp. 400-408
2015 Multivariate analysis of PRISMA optimized TLC image for predicting antioxidant activity and identification of contributing compounds from Pereskia bleo. Biomedical Chromatography, 29 (12) pp. 1826-1833
2015 Phytochemical and biological features of Phyllanthus niruri and Phyllanthus urinaria harvested at different growth stages revealed by H-1 NMR-based metabolomics. Industrial Crops and Products, 77 () pp. 602-613
2015 Phytochemical diversity of Clinacanthus nutans extracts and their bioactivity correlations elucidated by NMR based metabolomics. Phytochemistry Letters, 14 () pp. 123-133
2015 Relationship between metabolites composition and biological activities of phyllanthus niruri extracts prepared by different drying methods and solvents extraction. Plant Foods for Human Nutrition, 70 (2) pp. 184-192
2014 Chemical characterization and antioxidant activity of three medicinal Apiaceae species. Industrial Crops and Products, 55 () pp. 238-247
2014 Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model. Journal of Food Chemistry and Nutrition, 2 (1) pp. 43-51
2014 Effects of different drying methods and storage time on free radical scavenging activity and total phenolic content of cosmos caudatus. Antioxidants, 3 (2) pp. 358-370
2014 GC-MS-Based metabolite profiling of cosmos caudatus leaves possessing alpha-glucosidase inhibitory activity. Journal of Food Science and Technology, 79 (6) pp. C1130-C1136
2014 Orthogonal partial least squares model for rapid prediction of antioxidant activity of Pereskia bleo by fourier transform infrared spectroscopy. Analytical letters, 47 (12) pp. 2061-2071
2014 The influence of deep frying using various vegetable oils on acrylamide formation in sweet potato (Ipomoea batatas L. Lam) chips. Journal of Food Science and Technology, 79 (1) pp. T115-T121
2013 Analysis of chicken fat as adulterant in butter using Fourier transform infrared spectroscopy and chemometrics. Grasas y Aceites International JOurnal of Fats and Oils, 64 (4) pp. 349-355
2013 Analysis of chicken fat as adulterant in butter using fourier transform infrared spectroscopy and chemometrics. Grasas y Aceites, 64 (4) pp. 349-355
2013 Antioxidant and alpha-glucosidase activities of phyllanthus niruri extracted with different solvents. The Open Conference Proceedings Journal, () pp.
2013 Application of FTIR-ATR spectroscopy coupled with multivariate analysis for rapid estimation of butter adulteration. Journal of Oleo Science, 62 (8) pp. 1-8
2013 Authentication analysis of butter from beef fat using Fourier Transform Infrared (FTIR) spectroscopy coupled with chemometrics. International Food Research Journal, 20 (3) pp. 1383-1388
2013 Authentication analysis of butter from beef fat using Fourier Transform Infrared (FTIR) spectroscopy coupled with chemometrics. International Food Research Journal, 20 (3) pp. 1383-1388
2013 Comparison of partial least squares and artificial neural network for the prediction of antioxidant activity in extract of pegaga (centella) varieties from H-1 nuclear magnetic resonance spectroscopy. Food Research International, 54 () pp. 852-860
2013 Cosmos caudatus as a potential source of polyphenolic compounds: optimisation of oven drying conditions and characterisation of its functional properties. Molecules , 18 () pp. 10452-10464
2013 Headspace solid-phase microextraction gas chromatography–mass spectrometry determination of volatile compounds in different varieties of African star apple fruit (Chrysophillum albidum). Food Chemistry, 141 () pp. 2089-2097
2013 Quantification of Escherichia coli O157:H7 in organic vegetables and chickens. International Food Research Journal, 20 (2) pp. 1023-1029
2013 Risk of Escherichia coli O157:H7 transmission linked to the consumption of raw milk. International Food Research Journal, 20 (2) pp. 1001-1005
2013 Simultaneous determination of aflatoxins, ochratoxin a, and zearalenone in cereals using a validated HPLC-FLD method and PHRED derivatization system. Journal of Liquid Chromatography & Related Technologies, 36 (5) pp. 600-617
2012 1H-NMR-based metabolomics approach to understanding the drying effects on the phytochemicals in Cosmos caudatus. Food Research International, 49 (2) pp. 763-770
2012 Antioxidant activity of different extracts from leaves of Pereskia bleo (Cactaceae). Journal of Medicinal Plants Research, 6 (15) pp. 2932-2937
2012 Biochemical properties of red tilapia (Oreochromis niloticus) protein hydrolysates. International Food Research Journal, 19 (1) pp. 183-188
2012 Discrimination of three Pegaga (Centella) varieties and determination of growth-lighting effects on metabolites content based on the Chemometry of 1H Nuclear Magnetic Resonance spectroscopy. Journal of Agricultural and Food Chemistry, 60 (1) pp. 410-417
2012 High-performance liquid chromatographic determination of 5-hydroxymethyl furfural in roasted plantain cultivars. Journal of Food, Agriculture & Environment, 10 (3&4) pp. 99-103
2012 Influence of growth stage and season on the antioxidant constituents of Cosmos caudatus. Plant Foods for Human Nutrition, 67 (4) pp. 344-350
2012 Oxidative behaviour of four Malaysian edible plant extracts in model and food oil systems. Journal of Medicinal Plants Research, 6 (9) pp. 1556-1561
2012 Plants’ metabolites as potential antiobesity agents. The ScientificWorld Journal, 436039 () pp. 1-8
2012 Role of health hazardous ethephone in nutritive values of selected pineapple, banana and tomato. Journal of Food, Agriculture & Environment, 10 (2) pp. 247-251
2012 Role of health hazardous ethephone on nutritive values of selected pineapple, banana and tomato. Journal of Food, Agriculture & Environment, 10 (2) pp. 247-251
2012 UPLCeMS/MS for simultaneous determination of aflatoxins, ochratoxin A, zearalenone, DON, fumonisins, T-2 toxin and HT-2 toxin, in cereals. Food Control, 25 (2) pp. 647-653
2012 Volatile compounds of roasted and steamed Malaysian tropical almond nut (Terminalia catappa L.). International Journal of Food Properties, 15 (5) pp. 1120-1132
2011 Comprehensive extraction method integrated with NMR metabolomics : a new bioactivity screening method for plants, adenosine A1 receptor binding compounds in orthosiphon stamineus Benth. Analytical Chemistry, 83 (17) pp. 6902-6906
2011 Discrimination of young and mature leaves of Melicope ptelefolia using 1H NMR and multivariate data analysis. Food Chemistry, 126 (2) pp. 640-645
2011 Metabolic characterization of green pods from Vanilla planifolia accessions grown in La Réunion. Environmental and Experimental Botany, 72 (2) pp. 258-265
2011 Metabolomics for bioactivity assessment of natural products. Phytotherapy Research, 25 (2) pp. 157-169
2011 Sample preparation optimization for the simultaneous determination of mycotoxins in cereals. European Food Research and Technology, 232 (4) pp. 723-735
2011 Screening of selected Malaysian plants against several food borne pathogen bacteria. International Food Research Journal, 18 (3) pp. 1195-1201
2011 Simultaneous detection of 12 mycotoxins in cereals using RP-HPLC-PDA-FLD with PHRED and a post-column derivatization system. Food Additives & Contaminants: Part A, 28 (4) pp. 494-501
2010 Application of two dimensional thin layer chromatography pattern comparison for fingerprinting the active compaounds in the leaves of Vitex Trifolia linn processing anti-tracheospasmolytic activity . Journal of Liquid Chromatography & Related Technologies, 33 () pp. 214-224
2010 Application of two dimensional thin layer chromatography pattern comparison for fingerprinting the active compounds in the leaves of Vitex trifolia Linn possessing anti-tracheospasmolytic activity. Journal of Liquid Chromatography & Related Technologies, 33 (2) pp. 214-224
2010 Cannabinoid CB1 receptor binding and acetylcholinesterase inhibitory activity of Sceletium tortuosum L.. International Food Research Journal, 17 (2) pp. 349-355
2010 Extraction of fish oil from the skin of Indian mackerel using supercritical fluids. Journal of Food Engineering, 99 (1) pp. 63-69
2010 Fatty acid compositions of fish oil extracted from different parts of Indian mackerel (Rastrelliger kanagurta) using various techniques of supercritical CO2 extraction. Food Chemistry, 120 (3) pp. 879-885
2010 Isolation of individual hop iso-α-acids stereoisomers by β-cyclodextrin. Food Chemistry, 119 (1) pp. 354-357
2009 Adenosine A1 receptor binding activity of methoxy flavonoids from orthosiphon stamineus. Planta Medica, 75 (2) pp. 132-136
2009 Identification of possible compounds possessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis. Journal of Liquid Chromatography & Related Technologies, 32 () pp. 2906-2916
2009 Metabolic changes in different developmental stages of vanilla planifolia pods. Journal of Agricultural and Food Chemistry, 57 (17) pp. 7651-7658
2009 Storage stability of fish oil from Langkawi Island, Malaysia. Food Science and Technology Research, 15 (6) pp. 591-598
2007 NMR assignment of iso-α-acids from isomerised extracts of humulus lupulus L. cones. Phytochemical Analysis , 18 () pp. 371-377
2006 High performance liquid chromatographic method for Iso-a-Acids. Journal of Liquid Chromatography & Related Technologies, 29 (2) pp. 293-302
2005 Anti-inflammatory activities of Cinnomomum burmanni Bl. Food Science and Biotechnology, 14 (2) pp. 223-227
Conference or Workshop Item

2020 Bioassay: Zebrafish as a new animal model in pharmacology. In: World Class Visiting Professor Programe 2020,
2020 How to get published in a scientific journal. In: Webinar Penulisan dan Penerbitan Artikel Pada Jurnal Internasional Bereputasi Fakultas Teknologi Pertanian Universitas Brawijaya,
2020 Metabolomics and multivariate data analysis. In: Continues Learning Series (Webinar), Post Graduate Student Society Kulliyyah of Pharmacy, International Islamic University Malaysia,
2020 Metabolomics in medicinal herbal science. In: General Lecture of Metabolomics #3, Tropical Biopharmaca Research Center, Metabolomics Research Cluster, IPB University,
2020 Metabolomics: A new approach in functional food researches. In: Studium Generale Faculty of Agriculture, University of Sultan Ageng Tirtayasa,
2020 Metabolomics: A novel approach in pharmacognosy researches. In: Jambi Medical And Health Science International Conference (Jamhesic) 2020,
2020 Phytopharmaca: Metabolomics in herbal science. In: World Class Visiting Professor Programe 2020,
2020 Zebrafish: a promising animal model in pharmacology. In: Guest Lecture “Nutrasetika dan Pangan Fungsional “, Faculty of Agricultural Technology, Universitas Brawijaya, Malang, Indonesia,
2019 Metabolomics as new tool in pharmacognosy. In: Adjunct Professor Programme 2019, Universistas Airlangga,
2019 Multivariate data analysis for metabolomics. In: Adjunct Professor Programme 2019, Universistas Airlangga,
2019 Multivariate data analysis-NMR and LCMS. In: Metabolomics Workshop, Agro-Biotechnology Institute Malaysia and Genom Malaysia,
2019 Zebrafish model for screening tool in pharmacognosy. In: Adjunct Professor Programme 2019, Universistas Airlangga,
2018 Metabolomics : a new perspective in pharmaceutical industries. In: NMR based Metabolomics Workshop: Developed Biomaterial Product by Metabolomics Technique using Fast Spectrometry Method,
2018 Phytochemical constituents, a-glucosidase inhibitory activity and preliminary acute toxicity studies of the ethanol-water extracts of Salacca zalacca fruits in rats. In: 1st International Symposium on Herbal Medicine, Pre-conference of 3rd AMDI International Biohealth Sciences Conference (IBSC) 2018,
2017 Bioassays activity and FT-IR analysis of clinacanthus nutans (Burm F.) lindau leaves extracts. In: 2nd International Anatomical and Biomedical Scientific Conference 2017,
2017 Evaluation of antioxidant activities of various extracts from Dialium indium var. indium L. fruits. In: International Conference on Natural Products (ICNP 2017),
2017 Evaluation of antioxidants activity of Momordica charantia using LC-MS metabolomics approach. In: 2nd International Anatomical and Biomedical Scientific Conference 2017,
2017 FT-IR- based metabolomics approach to characterize the α-glucosidase inhibitory activity of Salak fruit. In: International Malaysian-French Scientific Conference (IMFSC 2017),
2017 In vitro antioxidant activities and gas-chromatography-mass spectrometry (GC-MS) analysis of antioxidant active fractions of Dialium indum var. indum L. fruit. In: International Malaysian-French Scientific Conference (IMFSC 2017): Inspired by nature, delivered through science for a better world,
2017 Insilico and invitro investigations of alpha-glucosidase inhibitory activity of phenolic constituents of tetracera indica. In: 2nd International Anatomical and Biomedical Scientific Conference 2017,
2017 Metabolomics: a new tool in herbal standardization and bioactivity assessment. In: 2nd International Seminar and Expo on Jamu (2nd ISEJ),
2017 Multivariate data analysis. In: Workshop on Metabolomics: Applying LC-MS and NMR Based Metabolomics Approaches in Natural Products Research,
2017 Porcupine bezoar: in vitro antioxidant and anti-proliferative effects. In: 2nd International Anatomical and Biomedical Scientific Conference (IABS) 2017,
2017 Standardization of Malaysia herbs using metabolomics approach. In: Asian Oceania Metabolomics Forum,
2016 Cancer chemoprevention study of luffa aegyptiaca (sponge gourd) seed extract on human breast cancer cell lines (MCF-7). In: 3rd Pan Asian Biomedical Science Conference 2016,
2016 Identification of antioxidants in Momordica charantia fruit using GC-MS metabolomics approach. In: International Conference on Natural Products 2016 (ICNP 2016),
2016 Isolation and identification of flavonoids from Tetracera indica Merr. (Dilleniaceae) leaves. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016),
2016 Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics. In: 2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016,
2016 Metabolomics as a tool in identification of bioactive compounds. In: 1st Annual Pharmacy Conference : Eksplorasi Keanekaragaman Hayati Indonesia Untuk Pengembangan Jamu Berbasis Saintifik,
2016 Metabolomics in herbal standardization and bioactivity assessment. In: The 2nd International Conference on Science and Technology,
2016 Pharmacological activities and comprehensive metabolite profiling of Clinacanthus nutans extract and fractions. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016),
2016 Understanding of anti-cancer properties of Neolamarckia cadamba (Kalempayan) leaves extract on breast cancer cell. In: 3rd Pan-Asian Biomedical Science Conference 2016 (3rd PABSC),
2015 Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars. In: International Conference on Natural Products 2015 (ICNP 2015),
2015 Evaluation of anti-diabetic properties of cosmos Caudatus leaves in obese-diabetic induced rats. In: 8th Asian Network of Research on Antidiabetic Plants (ANRAP), International Seminar 2015,
2015 Identification of alpha-glucosidase inhibitors in Cosmos caudatus leaves using GC-MS based metabolomics. In: 29th Scientific Meeting of Malaysian Society of Pharmacology and Physiolgy (MSPP),
2015 Metabolomics for bioactivity assessment of natural products. In: The 49th Pokjanas TOI International Seminar,
2015 Recent progress on the development of herbal medicine in Malaysia. In: International Seminar on 1st APTFI Congress,
2015 Screening of various parts of phaleria macrocarpa plants for α-glucosidase inhibitory activity. In: International Conference on Natural Product 2015 (ICNP),
2014 Adulteration test of honey using spectroscopy based metabolomics. In: Seminar on Competitive and Sustainable Beekeeping Industry,
2014 Evaluation of anti-diabetic properties of cosmos caudatus kunth leaves in obese-diabetic induced rat using metabolomics approach. In: International Health Conference IIUM 2014,
2014 Multivariate calibration of fourier transform infrared spectra in predicting anti-diabetic activity of momordica charantia fruit. In: International Health Conference IIUM 2014,
2013 Application of TLC-based metabolomics to identify bioactive compounds possessing adenosine A1 receptor binding activity in Misai Kucing (Orthosphon stamineus) leaves. In: 27th Scientific Meeting of Malaysian Society of Pharmacology and Physiology (MSPP2013),
2013 Discrimination of Alternanthera sessilis of different origins in Malaysia using FT-IR and two-dimensional infrared correlation spectroscopy and multivariate data analysis. In: International Conference on Natural Products 2013 (ICNP 2013),
2013 Effect of differentsSolvents extraction on antioxidant activity of Ipomoea aquatica. In: International Conference on Natural Products 2013 (ICNP 2013),
2013 Evaluation of anti-hyperlipidemia activity of Cosmos caudatus leaves in hyperlipidemic induced rat. In: 2nd Asian Regional Conference on System Biology ,
2013 Metabolomics in food safety and quality control. In: International Food Safety Conference 2013,