Dr. Mohd Hafidz Mahamad Maifiah graduated in Bachelor of Biomedical Science (Hons) and Master of Science (Biotechnology Engineering) from the International Islamic University Malaysia (IIUM). He then completed his PhD in Pharmaceutical Science from the Monash Institute of Pharmaceutical Science (MIPS), Australia in 2017. His PhD thesis elucidated the mechanisms of actions of polymyxins mono- and combination therapy against multidrug-resistant Gram-negative bacteria Acinetobacter baumannii and Pseudomonas aeruginosa adopted metabolomics and transcriptomics approaches. Currently, Dr. Mohd Hafidz is an academic staff at the International Institute for Halal Research and Training (INHART), IIUM serves as the Head of Postgraduate Management. His research interests cover the areas of halal food and pharmaceutical, plant natural products for bioactive compounds, bacterial resistance, metabolomics, halal supply chain and cold chain management.   

• Medical And Health ~ Medical And Health Sciences ~ Phamaceutical Industry ~ Natural Products - Herbal Plant/antimicrobial
• Natural Science ~ Bioinformatics ~ Systems Biology ~ Cellular Metabolomics - microbial metabolomics
• Agricultural ~ Agricultural Science And Technology ~ Food Sciences and Nutrition ~ Halal Products - Halal alternative ingredients
• Natural Science ~ Biological Sciences ~ Microbiology ~ Bacteriology - Antimicrobial/Polymyxin/Antimicrobial resistance
• Biotechnology ~ Biotechnology ~ Medical Biotechnology ~ Biomaterial - Biocellulose

• 2021: Member of Profesional Body / Association: (Ordinary Member ), Malaysian Society for Microbiology

FINAL YEAR PROJECT I	2022/2023 2021/2022
FINAL YEAR PROJECT II	2022/2023
HALAL ASSURANCE SYSTEM	2022/2023 2021/2022
HALAL AUDIT AND CERTIFICATION	2022/2023 2021/2022 2020/2021
HALAL PHARMACEUTICALS, COSMETICS & PERSONAL CARE PRODUCTS	2022/2023 2021/2022 2020/2021
RESEARCH METHODOLOGY	2020/2021 2019/2020
RESEARCH METHODOLOGY (QUALITATIVE)	2019/2020 2018/2019
RESEARCH METHODOLOGY (QUANTITATIVE - MSC)	2018/2019
RESEARCH METHODOLOGY (QUANTITATIVE)	2019/2020
SEMINAR	2018/2019 2017/2018
SUSTAINABLE DEVELOPMENT: ISSUES, POLICIES AND PRACTICES	2021/2022
SUSTAINABLE DEVELOPMENT: ISSUES, PRINCIPLES AND PRACTICES	2022/2023

Completed

2020 - 2020	Certified Halal Executive Training
2019 - 2019	Certified Halal Executive Training
2018 - 2021	Synergistic killing of novel combinations of `old? polymyxin drug and medicinal plant extracts targeting Gram-negative bacteria

On-Going

2022 - Present	Sample analysis by INHART Laboratory
2021 - Present	Synergistic Antibacterial Activity of Novel Exogenous Metabolite-polymyxin Combinations against Klebsiella Pneumoniae
2019 - Present	Deciphering the mechanism of action of polymyxins on pentose phosphate pathway metabolism in Acinetobacter baumannii in discovering novel antibiotic targets
2018 - Present	Antibacterial activity of phenolic compounds from Carica papaya seed extract as food preservative.
2018 - Present	Data Management of Various Non-Halal Adulterations and Development of Portable Halal Device

Article

2022	Bacterial metabolomics: sample preparation methods. Biochemistry Research International, 2022 (9186536) pp. 1-14
2022	Combination of polymyxin B and Aquilaria malaccensis extract enhanced the killing and inhibited the growth of Acinetobacter baumannii and Klebsiella pneumoniae. Malaysian Journal of Microbiology, 18 (1) pp. 27-36
2022	Deciphering the action of polymyxins on pentose phosphate pathway metabolism in Acinetobacter Baumannii: a metabolite-based target towards safe antibiotic treatment. IIUM Journal of Orofacial and Health Sciences, 3 (Supplement 1) pp. 9-9
2022	Exogenous metabolite feeding on altering antibiotic susceptibility in Gram-negative bacteria through metabolic modulation: a review. Metabolomics, 18 (47) pp. 1-12
2022	In silico genome-scale metabolic modeling and in vitro static time-kill studies of exogenous metabolites alone and with polymyxin B against Klebsiella pneumoniae. Frontiers in Pharmacology, () pp. 1-10
2022	Logo, sijil halal hindar rasa ragu pengguna. Berita Harian Online, 25 Mar 2022 () pp.
2021	Novel antimicrobial development using genome-scale metabolic model of Gram-negative pathogens: a review. The Journal of Antibiotics, 74 (2) pp. 95-104
2020	Antibacterial activity of ethanolic leaf extract of Aquilaria malaccensis against multi-drug-resistant Gram-negative pathogen. Food Research, 4 (6) pp. 1962-1968
2020	Antibacterial test and toxicity of plant seed extracts: a review. Food Research, 4 ((Suppl. 1) (2020)) pp. 12-27
2020	Detection of pork in processed meat products by species-specific PCR for halal verification: food fraud cases in Hat Yai, Thailand. Food Research, 4 ((S1)) pp. 244-249
2020	Integriti halal jamin aspek keselamatan makanan. Berita Harian, () pp. 11
2020	Response surface optimization of yield of agarwood (Aquilaria malaccensis) leaf extract using Soxhlet extraction. International Journal of Recent Technology and Engineering (IJRTE), 8 (6) pp. 1926-1934
2020	The thrombolytic and cytotoxic effects of nigella sativa (L.) seeds: the prophetic medicine. International Journal of Halal Research, 2 (2) pp. 70-77
2019	Benchmarking of halal food products using similarity measures – a conceptual retrieval model. Journal of Information Systems and Digital Technologies, 1 (1) pp. 17-24
2019	In vivo anxiolytic and in vitro anti-inflammatory activities of water-soluble extract (WSE) of Nigella sativa (L.) seeds. Natural Product Research, 35 (16) pp. 2793-2798
2019	In vivo anxiolytic and in vitro anti-inflammatory activities of water-soluble extract (WSE) of Nigella sativa (L.) seeds. Natural Product Research, () pp. 1-6
2019	Metabolic responses to polymyxin treatment in acinetobacter baumannii ATCC 19606: integrating transcriptomics and metabolomics with genome-scale metabolic modeling. MSYSTEMS, 4 (1) pp. 1-15
2019	Revisiting an ‘old’ antibiotic class polymyxins by drug combination therapy targeting Gram-negative superbugs: Toyyiban perspective. Journal of Halal Industry and Services, 2 (1) pp. 1-12
2019	Supervised identification of Acinetobacter Baumanni strains using artificial neural network. Journal of Information Systems and Digital Technologies, 1 (2) pp. 16-23
2018	Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa. GigaScience, 7 (4) pp. 1-18
2018	Isolation and identification of bacteria-producing cellulose from tropical fruit for Halal capsule application. International Journal on Advanced Science, Engineering and Information Technology, 8 (4-2) pp. 1591-1596
2017	Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii. Scientific Reports, 7 () pp. 1-12
2016	Acinetobacter baumanniiphenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis. Proceedings of the National Academy of Sciences (PNAS), 113 (34) pp. 9599-9604
2016	Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii. Scientific Reports, 6 () pp. 1-17
2011	Molecular cloning and production of recombinant phytase from Bacillus Subtilis ASUIA243 in Pichia Pastoris. IIUM Engineering Journal, 12 (4) pp. 1
2011	Screening and optimization of media components for phytase production of ASUIA 279 in Pichia pastoris system using statistical design. Australian Journal of Basic and Applied Sciences, () pp.

Conference or Workshop Item

2021	Strengthening the efficiency of cold chain management in halal food industry by identifying the crucial barriers. In: Virtual International Halal Science Conference 21: "Enhancing and Strengthening Halal Industry through Science",
2019	Antibacterial test, toxicity and food application of plant seed extracts: a review. In: Global Halal Sphere Conference 2019 (GloHaS 2019),
2011	Screening and optimization of media components for phytase production of ASUIA 279 in Pichia pastoris system using statistical design. In: 2nd International Conference on Biotechnology Engineering (ICBioE 2011),

Book Section

2020	A conceptual framework highlighting barriers in cold chain management for Halal food products in South-East Asian countries. In: Routledge Taylor & Francis Group, ISBN: 978-0-367-34997-4, pp. 51-67
2020	A conceptual framework highlighting barriers in cold chain management for Halal food products in South-East Asian countries. In: Routledge Taylor & Francis Group, ISBN: 978-0-367-34997-4, pp. 51-67
2019	Global metabolic analyses of acinetobacter baumannii. In: Humana Press, ISBN: 978-1-4939-9117-4, pp. 321-328