Staff Directory


Tengku Muhamad Faris Syafiq Bin Tengku Zakaria

Academic Qualification

  • Ph.D in Stem Cell Research - Doctor of Philosophy, University of Manchester
  • Master in Pharmaceutical Sciences (Pharmaceutical Technology) - Masters Degree, International Islamic University Malaysia
  • Postgraduate Diploma in Islamic Studies - Post Graduate Diploma, International Islamic University Malaysia
  • Bachelor of Biomedical Science (Honours) - Bachelor Degree, International Islamic University Malaysia
  • Certificate Literacy in A.I. - Certificate, Others

Tengku Muhamad Faris Syafiq Bin Tengku Zakaria (Dr.)

Assistant Professor
IIUM Kuantan Campus

KULLIYYAH OF NURSING


fariss@iium.edu.my
7335


Expert Profile


Tengku Faris obtained his Phd in Stem cell Research in the United Kingdom. He is a keen researcher, specialising in disease modeling using stem cells. He interested in understanding molecular mechanism of kidney development and associated genetic diseases. His work revolved around making kidney organoids in-a-dish from reprogrammed pluripotent stem cells to recapitulate genetic kidney malformations. Upon stimulation, human induced pluripotent stem cell (hiPSCs) can be differentiated into nephron progenitors before forming metanephric kidney. These organoids are anticipated to contain most of the kidney cell types and can be utilised as an in vitro disease models. The CRISPR/Cas9 system can be integrated into these models to correct mutations. Although making another version of kidney that are morphologically identical and functioning could be challenging, it is not impossible. He envisioned that the research can accelerate production of biosynthetic or artificial kidney to serve as transplantation alternative.


Area of Specialisation


  • Natural Science ~ Biological Sciences ~ Genetics ~ Stem Cell - Genome Editing


Professional Membership


  • 2020 - 2021: Member of Profesional Body / Association: (Member), Tissue Engineering and Regenerative Medicine Society of Malaysia (TESMA)
  • 2020 - 2021: Member of Profesional Body / Association: (Member), Persatuan Genetik Malaysia (PGM)
  • 2021 - 2022: Member of Profesional Body / Association: (Life Member), Malaysian Society for Stem Cell Research and Therapy
  • 2021 - 2022: Member of Profesional Body / Association: (Associate Member), Malaysian Association for Cancer Research
  • 2022 - 2032: Member of Profesional Body / Association: (Life Member), Malaysian Society for Molecular Biology and Biotechnology (MSMBB)
  • 2022 - 2024: Member of Profesional Body / Association: (Member), Tissue Engineering and Regenerative Medicine International Society


Teaching Responsibilities


ANATOMY AND PHYSIOLOGY 1 2020/2021
ANATOMY AND PHYSIOLOGY 2 2021/2022
BIOCHEMISTRY FOR NURSING 2021/2022 2020/2021
ENTREPRENEURSHIP IN NURSING 2021/2022 2020/2021
FINAL YEAR RESEARCH PROJECT I 2021/2022 2020/2021
FINAL YEAR RESEARCH PROJECT II 2021/2022 2020/2021
GENERAL PATHOLOGY 2021/2022 2020/2021
INNOVATION IN NURSING 2021/2022 2020/2021
INTEGRATED NURSING SCIENCES (FINAL PROFESSIONAL EXAMINATION) 2021/2022
INTEGRATED NURSING SCIENCES(FINAL PROFESSIONAL EXAMINATION) 2020/2021
MICROBIOLOGY, IMMUNOLOGY AND PARASITOLOGY 2021/2022
SUSTAINABLE DEVELOPMENT: ISSUES, POLICIES AND PRACTICES 2021/2022


Research Projects


Completed
No data
On-Going
2021 - Present In Vitro Evaluation of Safety Profiles, Cellular Responses and Genotoxicity of Nanostructured Tin (IV) Oxide, SNO2 on Human-Derived Pluripotent Stem Cell Lines
2021 - Present INTEGRATION OF MAQASID AL-SHARI?AH AS A RECIPROCAL FRAMEWORK IN STEM CELL-DERIVED ORGAN SYNTHESIS
2021 - Present Development of Immersive Virtual Reality (IVR) Simulation Program as a Distraction Intervention in Acute and Chronic PAin Patients at Sultan Ahmad Shah Medical Centre @IIUM
2021 - Present Modelling genetic kidney malformations using CRISPR/Cas9-edited 3D organoids derived from pluripotent stem cells to understand pathomechanism of human kidney disorders
2020 - Present Establishment of Alkaline Phosphatase Monoclonal Antibody towards Fibroblast Cell Line of Sumatran Rhinoceros (Dicerorhinus sumatrensis)
2020 - Present Characterisation of Multiplex Probe Melting Curve Profile in a Single Fluorescence Channel for Mutation Detections.
2013 - Present IIUM MOLECULAR AND CELLULAR BIOLOGY RESEARCH CLUSTER (iMoleC)


Publications


Article

2018 Generation of functioning nephrons by implanting human pluripotent stem cell-derived kidney progenitors. Stem Cell Reports, 10 (3) pp. 766-779
2017 Flavonoids from Tetracera indica Merr. induce adipogenesis and exert glucose uptake activities in 3T3-L1 adipocyte cells. BMC Complimentary and Alternative Medicine, 17 (1) pp. 1-14
2016 Cytotoxic and anti-inflammatory activities of Garcinia xanthochymus extracts on cell lines. Makara Journal of Health Research, 20 (1) pp. 11-17
2016 Hypoglycaemic activity of ethanolic extract of Garcinia mangostana Linn. in normoglycaemic and streptozotocin-induced diabetic rats. BMC Complementary and Alternative Medicine, 16 () pp. 16-135
2015 Alpha-mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPAR gamma, GLUT4, and leptin expressions. Evidence-Based Complementary and Alternative Medicine, 15 () pp. 1-9
2013 Evaluation of antimicrobial activity exploration of the leaves extracts of Borreria articularis (Linn. F.). African Journal of Biotechnology, 12 (23) pp. 3662-3668
2013 Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent. Australian Journal of Basic and Applied Sciences, 7 (4) pp. 641-647
Conference or Workshop Item

2014 Effects of garcinia mangostana on adipocyte differentiation and glucose uptake regulation in 3T3-L1 cells. In: 1st International Conference on Industrial Pharmacy,
2014 Potential antidiabetic properties of G. mangostana Linn. on Streptozotocin-induced diabetic rats . In: IIUM Research, Invention & Innovation Exhibition (IRIIE 2014),
Book Section

2018 Health benefits of omega-3 in cardiovascular disease. In: IIUM Press, ISBN: 978-967-418-454-4, pp. 91-108