Tengku Faris obtained his Phd in Stem cell Research in the United Kingdom. He is a keen researcher, specialising in disease modeling using stem cells. He interested in understanding molecular mechanism of kidney development and associated genetic diseases. His work revolved around making kidney organoids in-a-dish from reprogrammed pluripotent stem cells to recapitulate genetic kidney malformations. Upon stimulation, human induced pluripotent stem cell (hiPSCs) can be differentiated into nephron progenitors before forming metanephric kidney. These organoids are anticipated to contain most of the kidney cell types and can be utilised as an in vitro disease models. The CRISPR/Cas9 system can be integrated into these models to correct mutations. Although making another version of kidney that are morphologically identical and functioning could be challenging, it is not impossible. He envisioned that the research can accelerate production of biosynthetic or artificial kidney to serve as transplantation alternative.

• Natural Science ~ Biological Sciences ~ Genetics ~ Stem Cell - Genome Editing

• 2020 - 2021: Member of Profesional Body / Association: (Member), Tissue Engineering and Regenerative Medicine Society of Malaysia (TESMA)
• 2020 - 2021: Member of Profesional Body / Association: (Member), Persatuan Genetik Malaysia (PGM)
• 2021 - 2022: Member of Profesional Body / Association: (Life Member), Malaysian Society for Stem Cell Research and Therapy
• 2021 - 2022: Member of Profesional Body / Association: (Associate Member), Malaysian Association for Cancer Research
• 2022 - 2032: Member of Profesional Body / Association: (Life Member), Malaysian Society for Molecular Biology and Biotechnology (MSMBB)
• 2022 - 2024: Member of Profesional Body / Association: (Member), Tissue Engineering and Regenerative Medicine International Society

ANATOMY AND PHYSIOLOGY 1	2020/2021
ANATOMY AND PHYSIOLOGY 2	2021/2022
BIOCHEMISTRY FOR NURSING	2021/2022 2020/2021
ENTREPRENEURSHIP IN NURSING	2021/2022 2020/2021
FINAL YEAR RESEARCH PROJECT I	2022/2023 2021/2022 2020/2021
FINAL YEAR RESEARCH PROJECT II	2021/2022 2020/2021
GENERAL PATHOLOGY	2021/2022 2020/2021
INNOVATION IN NURSING	2021/2022 2020/2021
INTEGRATED NURSING SCIENCES (FINAL PROFESSIONAL EXAMINATION)	2021/2022
INTEGRATED NURSING SCIENCES(FINAL PROFESSIONAL EXAMINATION)	2020/2021
MICROBIOLOGY, IMMUNOLOGY AND PARASITOLOGY	2021/2022
SUSTAINABLE DEVELOPMENT: ISSUES, POLICIES AND PRACTICES	2021/2022

Completed

No data

On-Going

2022 - Present	Strengthening the Functions of the Established Frozen At IIUM in Contributing to the Conservation Plans for Endangered Species in Malaysia
2022 - Present	Expanding Project of the First South East Asian Frozen Zoo at IIUM for Endangered Species in Malaysia
2021 - Present	INTEGRATION OF MAQASID AL-SHARI?AH AS A RECIPROCAL FRAMEWORK IN STEM CELL-DERIVED ORGAN SYNTHESIS
2021 - Present	In Vitro Evaluation of Safety Profiles, Cellular Responses and Genotoxicity of Nanostructured Tin (IV) Oxide, SNO2 on Human-Derived Pluripotent Stem Cell Lines
2021 - Present	Development of Immersive Virtual Reality (IVR) Simulation Program as a Distraction Intervention in Acute and Chronic PAin Patients at Sultan Ahmad Shah Medical Centre @IIUM
2021 - Present	Modelling genetic kidney malformations using CRISPR/Cas9-edited 3D organoids derived from pluripotent stem cells to understand pathomechanism of human kidney disorders
2020 - Present	Establishment of Alkaline Phosphatase Monoclonal Antibody towards Fibroblast Cell Line of Sumatran Rhinoceros (Dicerorhinus sumatrensis)
2020 - Present	Characterisation of Multiplex Probe Melting Curve Profile in a Single Fluorescence Channel for Mutation Detections.
2013 - Present	IIUM MOLECULAR AND CELLULAR BIOLOGY RESEARCH CLUSTER (iMoleC)

Article

2018	Generation of functioning nephrons by implanting human pluripotent stem cell-derived kidney progenitors. Stem Cell Reports, 10 (3) pp. 766-779
2017	Flavonoids from Tetracera indica Merr. induce adipogenesis and exert glucose uptake activities in 3T3-L1 adipocyte cells. BMC Complimentary and Alternative Medicine, 17 (1) pp. 1-14
2016	Cytotoxic and anti-inflammatory activities of Garcinia xanthochymus extracts on cell lines. Makara Journal of Health Research, 20 (1) pp. 11-17
2016	Hypoglycaemic activity of ethanolic extract of Garcinia mangostana Linn. in normoglycaemic and streptozotocin-induced diabetic rats. BMC Complementary and Alternative Medicine, 16 () pp. 16-135
2015	Alpha-mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPAR gamma, GLUT4, and leptin expressions. Evidence-Based Complementary and Alternative Medicine, 15 () pp. 1-9
2013	Evaluation of antimicrobial activity exploration of the leaves extracts of Borreria articularis (Linn. F.). African Journal of Biotechnology, 12 (23) pp. 3662-3668
2013	Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent. Australian Journal of Basic and Applied Sciences, 7 (4) pp. 641-647

Conference or Workshop Item

2014	Effects of garcinia mangostana on adipocyte differentiation and glucose uptake regulation in 3T3-L1 cells. In: 1st International Conference on Industrial Pharmacy,
2014	Potential antidiabetic properties of G. mangostana Linn. on Streptozotocin-induced diabetic rats . In: IIUM Research, Invention & Innovation Exhibition (IRIIE 2014),

Book Section

2018	Health benefits of omega-3 in cardiovascular disease. In: IIUM Press, ISBN: 978-967-418-454-4, pp. 91-108