Staff Directory


Fazia Adyani binti Ahmad Fuad

Academic Qualification

  • Biology - Doctor of Philosophy, University of Edinburgh
  • Bio Technology - Masters Degree, Universiti Kebangsaan Malaysia (UKM)
  • Biochemistry - Bachelor Degree, Universiti Kebangsaan Malaysia (UKM)

Fazia Adyani binti Ahmad Fuad (Dr.)

Assistant Professor
IIUM Gombak Campus

KULLIYYAH OF ENGINEERING


fazia_adyani@iium.edu.my
4577


Expert Profile


Fazia Adyani Ahmad Fuad is an Assistant Professor at the Department of Biotechnology Engineering, Faculty of Engineering. Fazia's academic path began with a BSc (Biochemistry), which was obtained from University Kebangsaan Malaysia (UKM) in 2004. She then furthered her studies for a Master's degree at the same institution, specialising in Plant Biotechnology and successfully completed her studies in 2008.
She later pursued her doctoral degree (Structural Biochemistry) at the University of Edinburgh, Scotland, UK. She was awarded her Ph.D in 2012 and served as a lecturer at Institute for Research in Molecular Medicine (INFORMM), Health Campus, University Science Malaysia, before joining IIUM in 2014. Fazia's Ph.D project focused on drug design and discovery analyses on specific protein targets, in collaboration with Université Catholique de Louvain, Brussels and National Institutes of Health (NIH), USA. Since then, she has published her work in a number of international conferences and ISI-indexed journals.
She also serves as an editorial review board for International Journal in Medical Sciences and Biotechnology, and a member of several international scientific societies. Currently, Fazia is interested in investigating the potential of specific enzymes that are involved in various metabolic pathways as chemotherapeutic targets. Her main interests include a combination of in silico drug design and biochemical analyses on specific protein targets, which allows further understanding of various protein-protein and protein-ligand interactions.


Area of Specialisation


  • Natural Science ~ Bioinformatics ~ Systems Biology ~ Other Systems Biology n.e.c. - Biology


Professional Membership


  • 2020 - 2020: Member of Profesional Body / Association: (Associate Member), Royal Society of Chemistry


Teaching Responsibilities


BIOTECHNOLOGY ENGINEERING LAB III 2018/2019 2016/2017 2021/2022 2019/2020 2020/2021 2017/2018 2015/2016
CELL AND TISSUE ENGINEERING 2015/2016 2014/2015
FINAL YEAR PROJECT II 2018/2019
MOLECULAR BIOLOGY AND GENETIC ENGINEERING 2021/2022 2015/2016 2017/2018 2018/2019 2019/2020 2016/2017 2020/2021
MOLECULAR FARMING (BIOMOLECULAR) 2015/2016 2016/2017
PROJECT I 2021/2022 2019/2020 2020/2021 2018/2019
SEMINAR 2014/2015 2015/2016


Research Projects


Completed
2017 - 2019 Fractionation and partial purification of active compounds from agarwood branch extract responsible for the cytotoxic/anticancer activity
2016 - 2021 Interrogating Novel Compounds for Improved Anti-dengue Therapies via Inhibition of Host's Glycolytic Pathway
2015 - 2019 Identification of Novel Antimalarial Agents for the Treatment of Knowlesi Malaria via in silico Screening and Enzynmatic Inhibition Analysis
On-Going
2020 - Present Investigating the Potential Use of an LED-Photodiode Pair as a Flow Velocimetry Imaging Technique for Non-Invasive Measurement of Peritoneal Dialysis Fluid
2020 - Present Confirmation, Validation, and Characterization of Antimalarial Drug (Artemisinin) Resistant K13 Selected Genes on Plasmodium Falciparum in Malaysian Isolates
2018 - Present Collagen-Like Protein from Selected Bacteria as Alternative For Non-Halal Collagen
2018 - Present ANAEROBIC CO-DIGESTION OF SEWAGE SLUDGE AND FOOD WASTE FOR BIOGAS PRODUCTION AND MICROBIAL COMMUNITY IDENTIFICATION
2006 - Present Bio-Process and Molecular Engineering Research Unit (BPMERU)


Publications


Article

2021 Virtual screening for potential inhibitors of human hexokinase II for the development of anti-dengue therapeutics. BioTech, 10 (1) pp. 1-28
2020 Effects off Daidzin and analogue off ganoderma sinensetin bacterially-expressed human hexokinase isofform 2 for anti-dengue drug design. Biological And Natural Resources Engineering Journal, 3 (2) pp. 27-34
2020 Virtual screening for potential inhibitors of human hexoki-nase ii for the development of anti-dengue therapeutics. MDPI Biotech, () pp.
2019 Antiproliferative activity of ionic liquid-graviola fruit extract against human breast cancer (MCF-7) cell lines using flow cytometry techniques. Journal of Ethnopharmacology, 236 () pp. 466-473
2019 Contemporary strategies and current trends in designing antiviral drugs against dengue fever via targeting host-based approaches. Microorganisms, 7 (9) pp. 1-28
2019 Identifying analogues of 2-deoxyglucose, alpha-d-glucose and beta-d-glucose-6-phosphate as potential inhibitors of human hexokinase ii for the development of anti-dengue therapeutics. Pertanika Journal of Science and Technology, 27 (4) pp. 1625-1647
2019 Plasmodial enzymes in metabolic pathways as therapeutic targets and contemporary strategies to discover new antimalarial drugs: a review. Asia-Pacific Journal of Molecular Biology and Biotechnology, 27 (4) pp. 38-53
2017 Screening potential inhibitors of lactate dehydrogenase from Plasmodium knowlesi via virtual screening approaches. Tropical Biomedicine, 34 (4) pp. 1-14
2016 Inhibitors of leishmania mexicana phosphoglycerate mutase identified by virtual screening and verified by inhibition studies. Sains Malaysiana, 45 (7) pp. 1113-1120
2014 Trypanosomatid phosphoglycerate mutases have multiple conformational and oligomeric states. Biochemical and Biophysical Research Communications, 450 () pp. 936-941
2011 Phosphoglycerate mutase from Trypanosoma brucei is hyperactivated by cobalt in vitro, but not in vivo. Metallomics, 3 () pp. 1310-1317
2008 Super binary vector system enhanced transformation frequency and expression level of polyhydroxyvalerate gene in oil palm immature embryo. Asian Journal of Plant Sciences, 7 (6) pp. 526-535
Conference or Workshop Item

2020 Interrogating novel compounds for improved anti-dengue therapies via inhibition of human hexokinase II (HKII). In: Nanotechnology Symposium 2020,
2020 Novel compounds as potential anti-dengue therapies verified via inhibition of human hexokinase isoform II. In: Kulliyyah of Engineering Research, Innovation and Commercialization Exhibition 2020 (KERICE '20),
2019 Elucidating the analogues of 3-bromopyruvate (3-BP) as inhibitors against human hexokinase II for the development of anti-dengue drugs. In: 8th International Molecular Biology And Biotechnology Congress (MOLBIOTECH),
2019 Expression and purification of soluble bacterially-expressed human hexokinase II in E.coli system. In: "9th International Conference on Biomedical Engineering and Technology, ICBET 2019",
2018 Analogues of 2-Deoxyglucose as inhibitor candidates for hexokinase II identified via virtual screening analyses. In: 5th International Conference on Biotechnology Engineering (ICBioE 2018),
2017 Identifying potential inhibitors of human hexokinase II for the development of anti-dengue therapeutics via virtual screening approaches. In: 4th Asian Regional Conference on Systems Biology,
2015 Potential novel inhibitors of trypanosomatid phosphoglycerate mutases through ligand-based and structure-based in silico approaches. In: Singapore Health and Biomedical Congress 2015,
2013 Multiple oligomeric and conformational states of trypanosomatid phosphoglycerate mutases. In: 18th Lorne Proteomics Symposium 2013,
Book Section

2018 Characterization of conformational and oligomeric states of proteins. In: Springer Nature Singapore, ISBN: 978-981-13-2256-3, pp. 167-178
2018 Characterization of conformational and oligomeric states of proteins. In: Springer Nature Singapore, ISBN: 978-981-13-2256-3, pp. 167-178
2018 Secondary metabolite research in Malaysia: current status and future prospects. In: IntechOpen, ISBN: 978-1-78923-643-9, pp. 101-111