Khairul Bariyyah Binti Abd Halim (Dr.)
Assistant Professor
IIUM Kuantan Campus
KULLIYYAH OF SCIENCE
kbariyyah@iium.edu.my
2621
Expert Profile
Following her graduation in Bioinformatics at the University of Malaya in 2005, she worked at the same university for one year as a tutor in the Department of Bioinformatics and Computational Biology. Then, she moved to University of East Anglia to do a MSc degree in Bioinformatics in September 2006. During her three-month MSc dessertation, she worked at the Genome Centre, John Innes Centre, Norwich. In 2008, she returned to Malaysia and worked a the Centre of Research in Computational Sciences and Informatics for Biology, Bioindustry, Environment, Agriculture and Healthcare (CRYSTAL), University of Malaya, Kuala Lumpur for one year as a research assistant. Then, she was awarded the Yayasan Khazanah - Oxford Centre for Islamic Studies Merdeka Scholarship to read for a D.Phil in Biochemistry under supervision of Prof Mark Sansom, the leader of the Structural Biology and Computational Biochemistry (SBCB) group in the Department of Biochemistry, University of Oxford. She completed her study with a D.Phil in Biochemistry awarded on 13 August 2014. She joined IIUM in November 2014, and now she is a lecture at the Department of Biotechnology, Kulliyyah of Science, IIUM Kuantan Campus.
Area of Specialisation
- Natural Science ~ Bioinformatics ~ Bioinformatics Tools, Platforms and Technologies ~ Biomodeling and Simulation
- MOLECULAR DYNAMIC SIMULATION, PROTEIN MODELING
Research Projects
Completed
2020 -
2023
|
In silico Evaluation of Newly Designed Thiourea Derivatives as Potential Chemopreventive Agents Against Cancer Through EGFR-TK Inhibition |
2018 -
2022
|
Quest on Finding Potential Ebola VP40 Inhibitors: Molecular Dockings and Molecular Dynamics Simulation Studies |
2017 -
2020
|
Computational investigation on the interaction of ?-Glucosidase with the cell wall component of pathogenic fungus, Macrophomina phaseolina |
2016 -
2020
|
Investigation Of Insulin-like Protein Of Some Malaysia Medicinal Plants For Diabetes Mellitus Treatment
|
2015 -
2019
|
Fundamental Study of the Structure of the Glycerol-3-Phosphate Acyltransferase (GPAT) Protein from Chlorella Sp. on Understanding the Mechanism of Lipid Synthesis |
2015 -
2019
|
The Mechanistic Role of Active Site Residues in Non-Stereospecific Haloacid Dehalogenase E (Dehe) Using Computational Approach |
On-Going
Publications
Article
2023 |
In silico study of Thiourea derivatives as potential epidermal growth factor receptor inhibitors.
Journal of Computational Biophysics and Chemistry,
22
(4)
pp. 453-472
|
2022 |
Computational studies of potential ebola vp40 inhibitors using bioactive compounds from medicinal plants of Malaysia.
Jurnal Teknologi (Sciences and Engineering),
84
(4)
pp. 183-190
|
2022 |
P-glycoprotein: new insights into structure, physiological function, regulation and alterations in disease.
Heliyon,
8
(6)
pp. 1-12
|
2022 |
Recent development on the synthesis of thiourea derivatives and effect of substituents on the anticancer activity: a short review.
Malaysian Journal of Analytical Sciences,
26
(5)
pp. 1047-1069
|
2021 |
Molecular docking analysis of designed ligands on VP40 of
Ebola Virus.
Malaysian Journal of Chemistry,
23
(2)
pp. 63-73
|
2021 |
Molecular Docking of Polyphenol Compounds from Anacardium occidentalewith Alpha-Glucosidase and Dipeptidyl-Peptidase-4 Enzymes.
Malaysian Journal of Fundamental and Applied Sciences,
17
(2)
pp. 202-216
|
2020 |
Computational quest for finding potential Ebola VP40 inhibitors: a molecular docking study = [pencarian pengiraan untuk mencari potensi perencat Ebola VP40: suatu kajian mengedok molekul].
Sains Malaysiana,
49
(3)
pp. 537-544
|
2020 |
In silico mutation on a mutant lipase from Acinetobacter haemolyticus towards enhancing alkaline stability.
Journal of Biomolecular Structure and Dynamics,
38
(15)
pp. 4493-4507
|
2020 |
Molecular docking and molecular dynamics
simulations studies on β-glucosidase and xylanase Trichoderma asperellum to predict degradation order of cellulosic components in oil palm leaves for nanocellulose preparation.
Journal of Molecular Structure and Dynamics,
()
pp. 1-14
|
2020 |
Science@IIUM Issue 3.
SCIENCE@IIUM,
(3)
pp. 1-40
|
2019 |
Science@IIUM Issue 2.
SCIENCE@IIUM,
(2)
pp. 1-40
|
2019 |
The mechanistic role of active site residues in non-stereo haloacid dehalogenase E(DehE).
Journal of Molecular Graphics and Modelling,
90
()
pp. 219-225
|
2018 |
CHNS analysis towards food waste in composting.
Journal Clean WAS,
2
(1)
pp. 6-10
|
2018 |
Homology modeling and docking studies of δ19-fatty acid desaturase from a Cold-tolerant Pseudomonas sp. AMS8.
PeerJ,
2018
(3)
pp. 1-21
|
2018 |
In silico study of carvone derivatives as potential neuraminidase inhibitors.
Journal of Molecular Modeling,
24
(4)
pp. 1-13
|
2018 |
Interaction of monomeric Ebola VP40 protein with a plasma membrane: a coarse-grained molecular dynamics (CGMD) simulation study.
Journal of Molecular Graphics and Modeling,
82
()
pp. 137-144
|
2018 |
Quantitative protein expression of Malaysian Phaleriamacrocarpa.
International Journal of Advances in Science Engineering and Technology , I,
6
(2)
pp. 18-22
|
2018 |
The discovery of physical properties of food waste in composting process..
International Journal of Engineering & Technology,
7
(2.29)
pp. 460-468
|
2017 |
In silico binding interactions of dehalogenase (Dehe) with various haloalkanoic acids.
Galeri Warisan Sains,
1
(1)
pp. 4-6
|
2017 |
Molecular dynamic simulation of space and earth-grown crystal structures of thermostable T1 lipase geobacillus zalihae revealed a better structure.
Molecules,
22
(10)
pp. 1-13
|
2015 |
Interactions of the EGFR juxtamembrane domain with PIP2-containing lipid bilayers: insights from multiscale molecular dynamics simulations.
Biochimica et Biophysica Acta,
1850
(5)
pp. 1017-1025
|
2014 |
Sidekick for membrane simulations: automated ensemble molecular dynamics simulations of transmembrane helices.
Journal of Chemical Theory and Computation,
()
pp. 2165-2175
|
Conference or Workshop Item
2019 |
The mechanistic role of active site residues in non-stereo
Haloacid Dehalogenase E (DehE).
In: 2nd International Conference on Biosciences & Medical Engineering 2019,
|
2018 |
A quest on finding new potential ebola vp40 inhibitors: molecular docking and molecular dynamics simulation studies.
In: Computer-aided Drug Design 2018,
|
2018 |
Quantitative protein expression of Malaysian Phaleria macrocarpa.
In: 151st IIER International Conference,
|
2017 |
Isolation and identification of chlorella-like species for potential application in biofuel production.
In: 9th Asian Federation of Biotechnology(AFOB) Regional Symposium 2017,
|
2016 |
Comparative analysis of the biomass and lipid yield of blue-green algae, freshwater and marine microalgae as potential candidate for biofuel feedstock.
In: 2nd International Conference on Oceanography and Sustainable Marine Production (ICOSMaP 2016),
|
2016 |
Quantification of total phenolic contents and their antioxidant scavenging capacity in selected herbs extract.
In: Medical Research Symposium & Pacific Partnership in conjunction with Kuantan Research Day 2016,
|
2016 |
The effect of particle size, methods and time of extraction on the natural antioxidant content and radical scavenging activity of Phyllanthus niruri.
In: Medical Research Symposium & Pacific Partnership in conjunction with Kuantan Research Day 2016,
|
2015 |
In silico study of the ErbB4 interactions with curcumin analogs.
In: 6th Regional Conference on Molecular Medicine (RCMM) in Conjunction with 2nd National Conference for Cancer Research 2015,
|
Monograph