Staff Directory


Izzat Fahimuddin Bin Mohamed Suffian

Academic Qualification

  • PhD in Pharmaceutical Science Research - Doctor of Philosophy, King's College London
  • Bachelor of Engineering - Bachelor Degree, Kobe University

Izzat Fahimuddin Bin Mohamed Suffian (Dr.)

Assistant Professor
IIUM Kuantan Campus

KULLIYYAH OF PHARMACY


izzat_fahimuddin@iium.edu.my
3054


Expert Profile


Dr. Izzat Fahimuddin Bin Mohamed Suffian joined Kulliyyah of Pharmacy as a lecturer in November 2016. He is currently an Assistant Professor in Drug Delivery and Nanomedicine. He was awarded the Look East Policy Programme Scholarship from the Public Service Department, Government of Malaysia (2006-2012) to complete his first degree in Bachelor of Engineering in Chemical Science and Engineering at the Department of Chemical Science and Engineering, Faculty of Engineering, Kobe University (Japan). He worked briefly as a research assistant at the Biochemical Engineering Laboratory, Kobe University where he focussed on studying the role of arginine in the arginine-rich domain of Hepatitis B Virus core particles on cell uptake using in vitro models. He was also awarded the Excellent Student Programme (PPC) Scholarship from Public Service Department, Government of Malaysia (2012-2016) to complete his PhD in Pharmacology and Pharmaceutical and Analytical Science from King’s College London, United Kingdom, which involves engineering targeted hepatitis B virus core particles for cancer therapy. During his PhD studies, Dr. Izzat was awarded the prestigious Wellcome Image Awards, which recognise the creators of the most informative, striking and technically excellent images that communicate significant aspects of biomedical science in 2014 and 2016. As well as being a previous Wellcome Image Award winner, he has also won a science photography competition organised by the Engineering and Physical Sciences Research Council (EPSRC) in 2014. He has developed an extensive experience in designing and developing novel nanoscale delivery systems including virus-like particles and liposomes. His current work involves pre-clinical translation of novel nanomaterials designed specifically for drug, siRNA, plasmid and radionuclide delivery for therapeutic or diagnostic applications. He reported the potential of Hepatitis B Virus core particles as nanocarriers in targeting HER2-positive metastatic abdominal cancer following intra-peritoneal administration in vivo. In 2020, Izzat has been selected as a fellow with other 52 among 300 academics from all over public universities in Malaysia, under a programme called CEO@Faculty Programme 2.0 Cycle 3. This programme is organised by Ministry of Education, aimed at exposing university lecturers below 40 years old with a doctoral degree to the rudiments and operations of the industry. The programme celebrates the CEOs who have voluntarily accepted the task to coach young university lecturers to become future leaders. Currently, Izzat is attached with Datuk Nora A. Manaf, Chief Group Human Capital, Maybank Group Berhad, under this programme.   


Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Biomedical Sciences ~ Nanomedicine - Drug delivery


Professional Membership


  • 2019 - 2020: Member of Profesional Body / Association: (Co-opted Exco Member), The Malaysia Local Chapter of the Controlled Release Society (MyCRS)


Teaching Responsibilities


Drug Abuse 2017/2018
IMMUNOLOGY 2019/2020 2018/2019 2017/2018
NUCLEAR PHARMACY 2020/2021 2019/2020 2018/2019 2017/2018
PHARMACEUTICAL BIOTECHNOLOGY & BIOPHARMACEUTICAL 2021/2022
PHARMACEUTICAL MICROBIOLOGY 2018/2019 2017/2018 2016/2017
RESEARCH PROJECT 1 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018
RESEARCH PROJECT 2 2021/2022 2020/2021 2019/2020 2018/2019
RESEARCH PROJECT-LITERATURE SEARCH 2020/2021 2019/2020 2018/2019
STERILE PROCESSES AND PRODUCTS 2021/2022


Research Projects


Completed
2018 - 2020 In vitro effect of Tamarindus indica as a potential anti-larvae of screwworm maggots obtained from goats with myiasis
On-Going
2021 - Present Hepatotoxicity Studies of Eltrombopag-Loaded PLGA_PEG polymeric Nanocapsules in ITP-Induced Mice Model
2021 - Present Optimisation, Assembly, Testing, Validation, and Scaling Up of the Nanotech COVID19 Rapid Test Kit
2019 - Present Assessment on suitable hydrocolloids for probiotic encapsulation enhancing its viablity and stability
2019 - Present Preparation, characterisation and cytotoxicity assay of damnacanthal-loaded polymeric nanocapsules for breast cancer therapy
2017 - Present Rheological and Physical Properties characterization of nanoparticles-hydrogel for topical oral drug of oral cancer (targeted drug delivery)
2017 - Present Formulation of 5-Fluorouracil-loaded EGFR-Targeted Hydrogel-Nanocapsule Hybrids for Oral Squamous Cell Carcinoma Therapy


Award & Recognition


02 May, 2017 Best Paper Presentation - ASIA International Multidisciplinary Conference 2017 International


Publications


Article

2021 Bioengineering of virus-like particles as dynamic nanocarriers for in vivo delivery and targeting to solid tumours. Advanced Drug Delivery Reviews, 180 () pp. 1-19
2021 Hydrogel-nanoparticle hybrids for biomedical applications: principles and advantages. Nanomedicine, 16 (2) pp. 81-84
2021 LCMS dataset on compounds in syzygium polyanthum (wight) walp. leaves variant from the East coast of Peninsular Malaysia. Data in Brief, 39 () pp.
2020 Hydrogel–nanoparticle hybrids for biomedical applications: principles and advantages. Nanomedicine, 16 (2) pp. 81-84
2019 Development of biodegradable sustained-release damnacanthal nanocapsules for potential application in in-vitro breast cancer studies. Pakistan Journal of Pharmaceutical Sciences, 32 (5) pp. 2155-2162
2018 Engineering human epidermal growth receptor 2‑Targeting hepatitis B virus core nanoparticles for siRNA delivery in vitro and in vivo. ACS Applied Nano Materials, xx (xx) pp. 1-14
2017 Engineering hepatitis B virus core particles for targeting HER2 receptors in vitro and in vivo. Biomaterials, 120 () pp. 126-138
2017 Yield optimisation of hepatitis B virus core particles in e. coli expression system for drug delivery applications. Scientific Reports, 7 () pp. 1-9
2015 Cationic liposome- multi-walled carbon nanotubes hybrids for dual siPLK1 and doxorubicin delivery in vitro. Pharmaceutical Research, 32 (10) pp. 3293-3308
2015 Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles. Nanobiotechnology, 13 () pp.
2011 Granting specificity for breast cancer cells using a hepatitis B core particle with a HER2-targeted affibody molecule. Journal of Biochemistry, 153 (3) pp. 251-256
Conference or Workshop Item

2021 Angiotensin-converting enzyme inhibition activity and LCMS analysis of Syzygium polyanthum (Wight) Walp leaves. In: National Symposium on Essential Oils, Plants, Cosmetic and Health,
2021 Mechanism of angiotensin converting enzyme (ACE) inhibition by Syzygium polyanthum wight (WALP.) leaves. In: IIUM Research Day 2021: An International Online Event for Life Sciences,
2021 Molecular binding interaction of angiotensin converting enzyme and 1-galloyl glucose, the major compound in Syzygium polyanthum leaves. In: 7th International Conference on Advancement in Science and Technology (iCAST2021),
Book Section

2021 In vitro angiotensin-converting enzyme (ACE) inhibition activity of Syzygium polyanthum leaves and its inhibition mechanism. In: Frontiers, ISBN: 978-2-88971-008-9, pp.