Staff Directory


Zalikha Binti Ibrahim

Academic Qualification

  • Ph.D in Computational and Theoretical Chemistry - Doctor of Philosophy, Universiti Putra Malaysia (UPM)
  • Master of Science (Chemistry) - Masters Degree, Universiti Teknologi Malaysia (UTM)

Zalikha Binti Ibrahim (Dr.)

Assistant Professor
IIUM Kuantan Campus

KULLIYYAH OF PHARMACY

Other's position:

Deputy Dean, Kulliyyah of Pharmacy


zalikha@iium.edu.my
3055


Expert Profile


Zalikha Ibrahim received her BSc (Hons) in Petroleum Chemistry from Universiti Putra Malaysia in year 2008. She continued her intellectual journey at Universiti Teknologi Malaysia and was awarded MSc in Chemistry in 2011. During her MSc, she collected experiences working on a quantitative structure-activity relationship project for her dissertation. She received her doctoral in Computational and Theoretical Chemistry from Universiti Putra Malaysia in 2017. Her PhD thesis related on elucidation of inhibition mechanism of ligands/inhibitors towards a calcium-dependent protein. She was awarded with IPTA Academic Training Scheme (SLAI) from International Islamic University Malaysia and Ministry of Higher Education throughout her doctoral study.


Area of Specialisation


  • Natural Science ~ Bioinformatics ~ Structural Bioinformatics ~ Molecular Dynamics Simulation


Teaching Responsibilities


ANTI-INFECTIVES AGENTS 2018/2019 2019/2020
BODY SYSTEM & THERAPEUTICS II : RESPIRATORY & URINARY SYSTEM 2020/2021
BODY SYSTEM II : RESPIRATORY & URINARY SYSTEM 2020/2021 2018/2019 2019/2020
BODY SYSTEM V : ENDOCRINE & REPRODUCTIVE SYSTEMS 2020/2021
COMPUTER AIDED DRUG DESIGN AND DISCOVERY 2018/2019 2019/2020
COMPUTER-AIDED DRUG DESIGN AND DISCOVERY 2020/2021
Drug Abuse 2017/2018
FUNDAMENTALS OF MEDICINAL CHEMISTRY 2016/2017 2018/2019 2019/2020 2020/2021 2017/2018
ORGANIC CHEMISTRY 2016/2017 2017/2018 2018/2019
PHARMACEUTICAL ANALYSIS I 2017/2018
PHARMACOLOGY OF THE PERIPHERAL NERVOUS SYSTEM 2018/2019
RESEARCH PROJECT 1 2019/2020 2020/2021
RESEARCH PROJECT 2 2020/2021
RESEARCH PROJECT-LITERATURE SEARCH 2019/2020 2018/2019


Research Projects


Completed
2018 - 2021 Identification of ?-Glucosidase Inhibitors from Psychotria malayana Leaf Extract using Liquid Chromatography-Mass Spectrometry-Based Metabolomics and Protein-Ligand Interaction with Molecular Docking
2016 - 2020 Isolation, Identification and Computational Studies of a-Glucosidase Inhibitors from Clinacanthus nutans (Burm F.) Lindau Leaves Extracts
On-Going
2019 - Present A Pharmacophore-based Virtual Screening Approach for Identifying Bioactive Compounds from Various Malaysian Plants As Potential Protein Arginine Deiminase IV (PAD4) Inhibitors.
2019 - Present Identification of new inhibitor of Protein Arginine Deiminase 4 (PAD4) by consensus docking and biological assay to treat Rheumatoid Arthritis
2019 - Present Identification of alpha-glucosidase inhibitors from Psychotria malayana Jack leaf using multi-platform metabolomics approach and protein-ligand interaction with molecular docking in treating diabetes mellitus
2018 - Present Characterization of neuromuscular and cardiovascular effects of non-conventional three finger toxins from Malaysian spitting cobra (Naja sumatrana) venom
2018 - Present Chemical analyses of various heteroatom ligands


Publications


Article

2021 Metabolomics-based profiling with chemometric approach to identify bioactive compounds in Salacca zalacca fruits extracts and in silico molecular docking. Arabian Journal of Chemistry, 14 (4) pp. 1-12
2020 Alpha-glucosidase inhibitory effect of psychotria malayana jack leaf: A rapid analysis using infrared fingerprinting. Molecules, 25 (18) pp. 1-11
2020 Characterization of α-glucosidase inhibitors from psychotria malayana jack leaves extract using LC-MS-based multivariate data analysis and in-silico molecular docking. Molecules, 25 (24) pp.
2020 Gas chromatography-mass spectrometry based metabolomics to Identify the alpha glucosidase inhibitors from flesh of salacca zalacca fruits and their molecular docking studies. Journal of Pharmacy & Bioallied Sciences, 12 (Supplement 2) pp. 886-887
2019 Antidiabetic and antioxidants activities of Clinacanthus nutans (Burm F.) Lindau leaves extracts. International Food Research Journal, 26 (1) pp. 319-327
2019 Cytotoxic xanthones isolated from calophyllum depressinervosum and calophyllum buxifolium with antioxidant and cytotoxic activities. Food and Chemical Toxicology, 133 () pp.
2019 Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking. Journal of Pharmaceutical Analysis, 9 (2) pp. 91-99
2019 Rapid investigation of α-glucosidase inhibitory activity of Clinacanthus nutans leaf using infrared fingerprinting. Vibrational Spectroscopy, 100 () pp. 22-29
2019 Toxicity study on Clinacanthus nutans leaf hexane fraction using Danio rerio embryos. Toxicology Reports, 6 () pp. 1148-1154
2018 Characterization of α-glucosidase inhibitors from clinacanthus nutans lindau Llaves by gas chromatography-mass spectrometry-based metabolomics and molecular docking simulation. Molecules, 23 (9) pp. 1-21
2018 Structure-based design of peptide inhibitors for Protein Arginine Deiminase Type IV (PAD4). Reference Module in Life Sciences, 2018 () pp. 1-12
2017 Synthesis and in-vitro bioactivity evaluation of new galactose and fructose ester derivatives of 5-aminosalicylic acid. Chemistry & Biodiversity, 14 (4) pp. e1600362-1
2016 In-silico identification of potential protein arginine deiminase IV (PAD4) inhibitors = Pengenalpastian in-silico yang berpotensi sebagai perencat protin arginina deiminase IV (PAD4)). Malaysian Journal of Analytical Sciences, 20 (6) pp. 1269-1277