Staff Directory


Kamal Rullah

Academic Qualification

  • Doctor of Philosophy (Pharmacy) - Doctor of Philosophy, National University of Malaysia
  • M.Sc - Masters Degree, Universitas Riau
  • B.Pharm - Bachelor Degree, Sekolah Tinggi Ilmu Farmasi Riau

Kamal Rullah (Dr.)

Assistant Professor
IIUM Kuantan Campus

KULLIYYAH OF PHARMACY


kamalrullah@iium.edu.my
4934


Expert Profile


Dr. Kamal Rullah obtained B.Pharm in 2007 from the Sekolah Tinggi Ilmu Farmasi Riau,  Apothecary (2008) from the Universitas Andalas and M.Sc (2011) from the Universitas Riau, Indonesia. Since 2008, he was appointed as a Lecturer in Sekolah Tinggi Ilmu Farmasi Riau, Indonesia. He earned his Ph.D Medicinal Chemistry in 2017 from Faculty of Pharmacy, Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur and during 2017-2019 he performed postdoctoral research fellow at the Nanotechnology and Catalysis Research Centre (NANOCAT) University of Malaya (UM), working on organic synthesis sulphur-based compound collaboration with leading R&D Europe companies. He joined the academic member at Kulliyah of Pharmacy (KOP), International Islamic University Malaysia (IIUM) in 2019. His research interests are design and synthesis of new-bioactive molecule for application in chemical biology and precious medicine.    



Area of Specialisation


  • Medical And Health ~ Medical And Health Sciences ~ Pharmacy ~ Medicinal Chemistry 84 - Drug Discovery and Drug Design Development
  • Natural Science ~ Chemical Sciences ~ Organic Chemistry ~ Medicinal Chemistry - Drug Synthesis


Teaching Responsibilities


ANTI-INFECTIVE AGENTS 2020/2021
BODY SYSTEM III : MUSCULOSKELETAL & SENSORY ORGANS 2019/2020
COMPUTER AIDED DRUG DESIGN AND DISCOVERY 2019/2020
COMPUTER-AIDED DRUG DESIGN AND DISCOVERY 2020/2021
FUNDAMENTALS OF MEDICINAL CHEMISTRY 2020/2021 2019/2020
HERBAL MEDICINE 2020/2021 2019/2020
NUCLEAR PHARMACY 2020/2021
PHARMACEUTICAL INSTRUMENTAL ANALYSIS 2020/2021
PHARMACEUTICAL ORGANIC CHEMISTRY 2019/2020
RESEARCH PROJECT-LITERATURE SEARCH 2020/2021


Research Projects


Completed
No data
On-Going
2021 - Present Encapsulation of Malaysian Patin Oil-loaded Alginate Microbeads Prototype for Supporting Children's Growth
2020 - Present Pharmacological Evaluation of a novel chloro-containing flavonoid molecule (KR-2001-KW) as an anticancer agent
2019 - Present Development and characterization of nanofibers patch containing nicotine using electrospinning: a novel approach as nicotine replacement therapy.


Award & Recognition


05 Feb, 2020 Reviewing award February 2020: Journal of Molecular Structure. - Elsevier Publisher International
07 Mar, 2018 Chairman - International Congress on Pure & Applied Chemistry (ICPAC 2018)-Cambodia International
19 Mar, 2014 The Best Poster Presentation - International Conference Natural Product (ICNP) 2014-Malaysia Natural Product Society (MNPS) International


Publications


Article

2021 Biomedical application of responsive ‘smart’ electrospun nanofibers in drug delivery system: A minireview. Arabian Journal of Chemistry, 14 (7) pp.
2021 In Silico Functional and Structural Insight of Prenylated Pyrazolocurcumin Derivative Associated with the PGE2 Inhibition through mPGES-1 Blocking. Materials Science Forum, 1025 () pp. 219-223
2021 In Silico Functional and Structural Insight of Prenylated Pyrazolocurcumin Derivative Associated with the PGE2 Inhibition through mPGES-1 Blocking. Materials Science Forum, 1025 () pp. 219-223
2020 Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: synthesis, biological activity, crystal structure analysis, and molecular docking studies. Bioorganic Chemistry, 94 () pp. 1-12
2020 Targeted delivery of 5-fluorouracil-1-acetic acid (5-FA) to cancer cells overexpressing epithelial growth factor receptor (EGFR) using virus-like nanoparticles. Scientific Reports, 10 (1) pp.
2019 Design and synthesis of a novel mPGES-1 lead inhibitor guided by 3D-QSAR CoMFA. Journal of Molecular Structure, 1196 () pp. 844-850
2019 Insights on the synthesis of asymmetric curcumin derivatives and their biological activities. European Journal of Medicinal Chemistry, 183 () pp.
2019 Oestrogenic activity of mimosine on MCF‐7 breast cancer cell line through the ERα‐mediated pathway. Chemical Biology and Drug Design, 93 (3) pp. 1-10
2019 Palladium‐catalysed cross‐coupling reactions for the synthesis of chalcones. Asian Journal of Organic Chemistry, 8 (8) pp. 1174-1193
2018 Hits-to-lead optimization of the natural compound 2,4,6-trihydroxy-3-geranyl-acetophenone (tHGA) as a potent LOX Inhibitor: synthesis, structure-activity relationship (SAR) study and computational assignment. Molecules, 23 (10) pp. 1-19
2018 Kajian dok molekul mengenai interaksi antara RNA-bergantung RNA polimerase virus denggi dan analog nukleosida = Molecular docking study of the interactions between dengue virus RNA-dependent-RNA polymerase and nucleoside analogues. Sains Malaysiana, 47 (3) pp. 517-522
2018 Synthesis, biological evaluation and docking studies of aurone derivatives on Xanthine oxidase enzyme. Jurnal Sains Kesihatan Malaysia (JSKM), 16 (1) pp. 135-143
2017 Suppression of PGE2 production via disruption of MAPK phosphorylation by unsymmetrical dicarbonyl curcumin derivatives. Medicinal Chemistry Research, 26 (12) pp. 3323-3335
2016 Effects of tocotrienols on insulin secretion-associated genes expression of rat pancreatic islets in a dynamic culture. Frontiers in Pharmacology, 7 () pp. 1-17
2016 Synthesis and effects of oxadiazole derivatives on tyrosinase activity and human SK-MEL-28 malignant melanoma cells. RSC Advances, 6 (76) pp. 72177-72184
2016 Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines. Bioorganic & Medicinal Chemistry Letters, 26 (10) pp. 2531-2538
2015 Molecular characterization, biological activity, and in silico study of 2-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-6-methoxy-4H-chromen-4-one as a novel selective COX-2 inhibitor. Journal of Molecular Structure, 1081 () pp. 51-61
2015 Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives. Bioorganic & Medicinal Chemistry Letters, 25 (16) pp. 3330-3337
2015 Probing the effects of fish oil on the delivery and inflammation-inducing potential of imiquimod. International Journal of Pharmaceutics, 490 () pp. 131-141
2015 Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxideinhibitors. Medicinal Chemistry Communication, 6 () pp. 1069-1080
2014 Inhibition of prostaglandin E-2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation. Bioorganic & Medicinal Chemistry Letters, 24 (16) pp. 3826-3834
2014 Synthesis and docking studies of 2,4,6-trihydroxy-3-geranylacetophenone analogs as potential lipoxygenase inhibitor. Molecules, 19 (8) pp. 11645-11659
2014 Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents. Molecules, 19 (10) pp. 16058-16081
Conference or Workshop Item

2019 Synthesis and SAR studies of new chromone derivatives as Inhibitors of PGE2 production. In: 1st Malaysian Association for Cancer Research (MACR) Scientific Conference (1st MSC) 2019,
Book Section

2020 Synthesis, In silico molecular docking modeling and pharmacophore mapping of (E)-3-(4-hydroxy-2,6-dimethoxyphenyl)-1-phenylprop-2-en-1- one as potential new inhibitor of microsomal prostaglandin E synthase-1. In: Trans Tech Publications Ltd, ISBN: 978-303571664-1, pp. 247-252